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CAS: 498-02-2
分子式: C9H10O3
分子量: 166.18
沸点: 295-300℃
熔点: 112-116℃
中文名称: 
4-羟基-3-甲氧基苯乙酮
4'-羟基-3-甲氧基苯乙酮
3-甲氧基-4-羟基苯乙酮
香草乙酮
1-(4-羟基-3-甲氧基苯基)乙酮
英文名称: 
Ethanone,1-(4-hydroxy-3-methoxyphenyl)-
3-Methoxy-4-hydroxyacetophenone
4-Hydroxy-3-methoxyacetophenone
1-(4-hydroxy-3-methoxyphenyl)-Ethanone
4'-hydroxy-3'-methoxy-acetophenon
1-(4-hydroxy-3-methoxyphenyl)ethanone
3-metoksy-4-hydroksyacetofenon
4'-hydroxy-3'-methoxyacetophenone
acetoguaiacon
acetoguaiacone
acetovanillone
acetovanilone
acetovanyllon
apocynin
apocynine
1-(4-hydroxy-3-methoxyphenyl)-ethanon
展开更多英文名
性质描述: 白色结晶性粉末。
用途: 有机合成中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
H792699MACKLIN4-羟基-3-甲氧基苯乙酮10mM in DMSO185元/1ml;   展开
储存:-20°C
H830242MACKLIN4'-羟基-3'-甲氧基苯乙酮98%30元/5g;   75元/25g;   280元/100g;   展开
储存:室温,密封
状态:白色到奶油色或淡黄色到淡棕色结晶粉末
H0261TCI4'-Hydroxy-3'-methoxyacetophenone>98.0%(GC)200元/25G;   490元/100G;   1500元/500G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C9H10O3 = 166.18
外观与形状(20℃)固体
Reaxys-RN637373
PubChem物质ID87570688
SDBS (AIST Spectral DB)6357
Merck Index (14)741
MDL编号MFCD00008747

技术规格

AppearanceWhite to Yellow to Orange powder to crystal
Purity(GC)min. 98.0 %
Melting point113.0 to 117.0 ℃
Solubility in Methanolfaint turbidity

物性(参考值)

熔点115 ℃
沸点300 ℃
最大吸收波长383(MeOH) nm
溶解性(易溶于)苯,氯仿,乙醚,醇

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#AM8800000
602333J&KAcetovanillone98.5%173元/25G;   412元/100G;   1378元/500G;   展开

基本信息

分子式C9H10O3
分子量166.17
熔点112-115
沸点263-265
闪点113
MDL编码MFCD00008747
Beilstein637373
Merck14,741
EINECS 编号207-854-5

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK2
RTECSAM8800000
TSCA
A10439Alfa Aesar4'-Hydroxy-3'-methoxyacetophenone98%338元/50g;   1491元/250g;   2979元/500g;   展开

应用
4'-Hydroxy-3'-methoxyacetophenone is used as an inhibitor of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, which is an enzyme responsible for reactive oxygen species production. It is also useful in the treatment of various inflammatory diseases and atherosclerosis. Further, it shows an anti-inflammatory activity and improves endothelial function by reducing oxidative stress. In addition to this, it is used for studying nitric oxide regulated processes in plants.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00008747

EINECS
207-854-5

分子式
C9H10O3

分子量
166.18

熔点
112-116°

沸点
295-300°

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in ethanol, chloroform, ether, hot water, benzene, ethyl acetate and dimethyl sulfoxide. Insoluble in petroleum ether.

Beilstein
637373

Merck
14,741

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

RTECS
AM8800000

TSCA

C10242Alfa AesarAcetovanillone98%691元/25g;   1442元/100g;   6400元/500g;   展开

基本信息

Ref#
10242

MDL
8747

分子式
C9 H10 O3

分子量
166.18

形态
White to cream cryst powder

178385Sigma-AldrichApocynin-CAS 498-02-2-CalbiochemA cell-permeable, anti-inflammatory phenolic compound that acts as a potent and selective inhibitor of NADPH oxidase.1113.94元/1 G;   展开

产品说明

一般描述

一种细胞可透过性抗炎酚,可作为 NADPH 氧化酶的有效和选择性抑制剂。还可阻断鼠巨噬细胞中过亚硝酸盐的形成。据报道,可通过激活 AP-1 增加谷胱甘肽的合成。研究表明,可防止巨噬细胞(10 mM)吞噬髓磷脂。
一种细胞可透过性抗炎酚类化合物,可作为 NADPH 氧化酶的有效和选择性抑制剂。研究表明,可阻断鼠巨噬细胞中过亚硝酸盐的形成。据报道,可通过激活 AP-1 增加谷胱甘肽的合成。还有有报道表明,可防止巨噬细胞(10 mM)吞噬髓磷脂。

包装

1 g in Plastic ampoule
用惰性气体包装

生化/生理作用

产物不与ATP竞争。
可逆:否
主靶
NADPH 氧化酶
细胞可渗透性:具有

警告

毒性:刺激性(B)

重悬

重悬后,等分并冷冻(-20°C)。储备溶液在-20°C下可稳定保存至多6个月。

其他说明

Abid, M.R., et al. 2000.FEBS Lett.486, 252.
Muijsers, R.B., et al. 2000.Br. J. Pharmacol.130, 932.
Lapperre, T.S., et al. 1999.FEBS Lett.443, 235.
Supinski, G., et al. 1999, J. Appl. Physiol.87, 776.
van der Goes, A., et al. 1998.J. Neuroimmunol.92, 67.
Hart, B.A., and Simmons, J.M.1992.Biotechnol.Ther.3, 3.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C9H10O3
分子量166.17
MDL编号MFCD00008747
NACRESNA.77

产品性质

质量水平100
测定≥98% (GC)
形式powder
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 white to off-white
溶解性DMSO: 10 mg/mL
ethanol: 20 mg/mL
运输ambient
储存温度−20℃
InChI1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3
InChI keyDFYRUELUNQRZTB-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 2
W508454Sigma-AldrichAcetovanillone≥98%, FG404.65元/;   1256.18元/100 G;   4959.99元/1 KG;   27437.5元/10 KG;   展开

产品说明

一般描述

乙酰香草酮是香草醛的结构类似物,主要存在于橡木桶陈酿的葡萄酒中。 它是一种强效的 NADPH 氧化酶抑制剂。

包装

10 kg in composite drum
100 g in poly bottle
1 kg in poly bottle
25 kg in fiber drum

基本信息

线性分子式HOC6H3(OCH3)COCH3
分子量166.17
Beilstein637373
EC 号207-854-5
MDL编号MFCD00008747
PubChem化学物质编号24902039
Flavis编号7.142
NACRESNA.21

产品性质

质量水平400
生物来源synthetic
等级FG
Halal
agencyfollows IFRA guidelines
reg. complianceEU Regulation 1223/2009
EU Regulation 1334/2008 & 872/2012
FDA 21 CFR 110
测定≥98%
bp263-265 ℃/17 mmHg (lit.)
mp112-115 ℃ (lit.)
文件see Safety & Documentation for available documents
性状检查vanilla
application(s)flavors and fragrances
食品过敏原no known allergens
致敏芳香化合物no known allergens
SMILES stringCOc1cc(ccc1O)C(C)=O
InChI1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3
InChI keyDFYRUELUNQRZTB-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 2
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
A10809Sigma-Aldrich4′-Hydroxy-3′-methoxyacetophenone98%369.85元/25 G;   1000.98元/100 G;   展开

基本信息

线性分子式HOC6H3(OCH3)COCH3
分子量166.17
Beilstein637373
EC 号207-854-5
MDL编号MFCD00008747
PubChem化学物质编号24890503
NACRESNA.22

产品性质

质量水平100
测定98%
bp263-265 ℃/17 mmHg (lit.)
mp112-115 ℃ (lit.)
SMILES stringCOc1cc(ccc1O)C(C)=O
InChI1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3
InChI keyDFYRUELUNQRZTB-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 2
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
PHL83252Apocyninphyproof® Reference Substance3048.57元/100 MG;   展开

产品说明

一般描述

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

基本信息

线性分子式HOC6H3(OCH3)COCH3
分子量166.17
Beilstein637373
MDL编号MFCD00008747

产品性质

等级primary reference standard
产品线phyproof® Reference Substance
测定≥95.0% (HPLC)
形式solid
manufacturer/tradenamePhytoLab
bp263-265 ℃/17 mmHg (lit.)
mp112-115 ℃ (lit.)
SMILES stringCOc1cc(ccc1O)C(C)=O
InChI1S/C9H10O3/c1-6(10)7-3-4-8(11)9(5-7)12-2/h3-5,11H,1-2H3
InChI keyDFYRUELUNQRZTB-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 2
909602AmethystAcetovanillone98.5%, 用于合成40元/5G;   156元/25G;   371元/100G;   1240元/500G;   展开

基本信息

分子式C9H10O3
分子量166.17
熔点112-115
沸点263-265
闪点113
MDL编码MFCD00008747
Beilstein637373
Merck14,741
EINECS 编号207-854-5

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK2
RTECSAM8800000
TSCA
227636FluorochemAcetovanillone95%220元/1g;   286元/25g;   1034元/100g;   2816元/500g;   展开

基本信息

CAS Number498-02-2
MDL NumberMFCD00008747

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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