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CAS: 497259-23-1
分子式: C27H30F3N3O3
分子量: 501.54
中文名称: 
α-amyloid precursor protein modulator-cas 497259-23-1-calbiochem
英文名称: 
(2S,5S)-(e,e)-8-(5-(4-(trifluoromethyl)phenyl)-2,4-pentadienoylamino)benzolactam, pkc activator v
用途: TPPB是苯并内酰胺衍生的可渗透细胞的蛋白激酶C (PKC) 活化物,Ki 值为11.9 nM。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
T878810MACKLINTPPB ≥99%1333元/1mg;   展开
储存:2-8℃
状态:浅黄色到黄色固体
565740Sigma-Aldrichα-Amyloid Precursor Protein Modulator-CAS 497259-23-1-CalbiochemA cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 4349.22元/1 MG;   展开

产品说明

一般描述

A cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblast AG06848. Displays a marked loss of tumor promoting activity.
A cell-permeable PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) but lacks any tumor promoting activity.

包装

1 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Target Ki: 11.9 nM for activating PKCα
Primary Target
PKC

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

其他说明

Kozikowski, A.P., et al. 2003. J. Med. Chem.46, 364.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C27H30F3N3O3
分子量501.54

产品性质

质量水平100
测定≥95% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
颜色 orange
溶解性methanol: 1 mg/mL
DMSO: 50 mg/mL
运输wet ice
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
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