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CAS: 495-69-2
分子式: C9H9NO3
分子量: 179.17
熔点: 188-191℃
中文名称: 
N-苯甲酰甘氨酸
N-苯甲酰基甘氨酸
马尿酸
苯甲酰氨基乙酸
苯甲酰甘氨酸
英文名称: 
benzoyl-glycine
hippuric
hippuricacid
Glycine,N-benzoyl-
N-Benzoylglycine
Benzoylaminoethanoic acid
Benaamidoacatic acid
Benzoylglycocoll
N-benzoyl-Glycine
Benzoyl glycine
Hippuric acid
acido ippurico
benzamidoacetic acid
benzoylglycine
n-benzoyl-glycin
phenylcarbonylaminoacetic acid
展开更多英文名
性质描述: 白色结晶。熔点186-187℃,相对密度1.371(20/4℃)。1g该品约可溶于250ml冷水、1000ml氯仿,400ml乙醚、60ml戊醇,溶于热水和热醇,不溶于苯、二硫化碳和石油醚。
生产方法: 由苯甲酰氯与氨基乙酸在氢氧化钠溶液中反应得到苯酰氨基乙酸钠,然后用盐酸酸化制得。将氨基乙酸溶于氢氧化钠溶液中,在30℃以下同时滴入苯甲酰氯及氢氧化钠溶液,使反应液始终呈碱性。加毕,搅拌30min。然后加盐酸酸化至pH为2,滤出粗品,用水重结晶,得马尿酸。原料消耗定额:氨基乙酸(90%)610kg/t、苯甲酰氯(60%)1520kg/t、液碱(30%)1960kg/t、盐酸(30%)900kg/t。
用途: 该品为医药、染料的中间体,用于生产荧光黄H8GL、分散荧光FFL等。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
H810747MACKLIN马尿酸分析对照品, 99%255元/250mg;   920元/1g;   展开
储存:室温,干燥,密封
状态:白色到灰白色结晶粉末
H810748MACKLIN马尿酸98%35元/25g;   85元/100g;   245元/500g;   849元/2.5kg;   展开
储存:室温,干燥,密封
状态:白色粉末,晶体和/或块状
H796205MACKLIN马尿酸10mM in DMSO455元/1ml;   展开
储存:-20°C
H0143TCIHippuric Acid>98.0%(T)100元/25G;   190元/100G;   690元/500G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C9H9NO3 = 179.18
外观与形状(20℃)固体
Reaxys-RN1073987
PubChem物质ID87570587
SDBS (AIST Spectral DB)1717
Merck Index (14)4716
MDL编号MFCD00002692

技术规格

AppearanceWhite powder to crystal
Purity(Neutralization titration)min. 98.0 %
Melting point189.0 to 194.0 ℃
Chloridemax. 0.05
Benzoic acidmax. 0.5 %

物性(参考值)

熔点190 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#MR8150000
600101J&KHippuric Acid98%72元/25G;   155元/100G;   466元/500G;   展开

基本信息

分子式C9H9NO3
分子量179.17
熔点187-191
MDL编码MFCD00002692
Beilstein1073987
Merck14,4716
EINECS 编号207-806-3

安全信息

图形或危害标志
提示语Danger
危险说明H302
H315
H318
H335
防范说明P261
P280
P305+P351+P338
WGK3
RTECSMR8150000
A12690Alfa AesarHippuric Acid98%477元/100g;   1649元/500g;   3094元/1000g;   展开

应用
Hippuric acid is used as a intermediate for the manufacturing medicine and other organic compounds. Hippuric acid can be used to study cell biology, chemical biology, bioactive small molecules, amino acid derivatives, peptide synthesis, chemical synthesis and nutrition. Hippuric acid has been used to inform the metabolism and urinary excretion of procyanidins.

备注
Store in cool dry place in tightly closed container. With good ventilation. Store away from oxidizing agent.

基本信息

MDL
MFCD00002692

EINECS
207-806-3

分子式
C9H9NO3

分子量
179.18

熔点
188-191°

密度
1.371

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in water.

Beilstein
1073987

Merck
14,4716

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

RTECS
MR8150000

TSCA

C15027Alfa AesarHippuric Acid98%442元/5g;   558元/100g;   1414元/500g;   6106元/2.5kg;   展开

基本信息

Ref#
15027

MDL
2692

分子式
C9 H9 N O3

分子量
179.17

112003Sigma-AldrichHippuric Acid98%565.59元/5 G;   679.1元/100 G;   1737.02元/500 G;   展开

产品说明

应用

马尿酸可用于研究细胞生物学、化学生物学、生物活性小分子、氨基酸衍生物、肽合成、化学合成和营养。马尿酸已被用于告知原花青素的代谢和尿排泄。

包装

5 g in glass bottle
100, 500 g in poly bottle

基本信息

线性分子式C6H5CONHCH2COOH
分子量179.17
Beilstein1073987
EC 号207-806-3
MDL编号MFCD00002692
PubChem化学物质编号57646893
NACRESNA.25

产品性质

质量水平200
测定98%
mp187-191 ℃ (lit.)
application(s)peptide synthesis
SMILES stringOC(=O)CNC(=O)c1ccccc1
InChI1S/C9H9NO3/c11-8(12)6-10-9(13)7-4-2-1-3-5-7/h1-5H,6H2,(H,10,13)(H,11,12)
InChI keyQIAFMBKCNZACKA-UHFFFAOYSA-N
Gene Informationrat ... Akr1b1(24192)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
8.20649Sigma-AldrichHippuric Acidfor synthesis396.98元/100 G;   展开

产品说明

分析说明

Assay (acidimetric): ≥ 97.5 %
Melting range (lower value): ≥ 186 °C
Melting range (upper value): ≤ 190 °C
Identity (IR): passes test

基本信息

经验(实验)分子式C9H9NO3
分子量179.17
MDL编号MFCD00002692
EC索引号207-806-3

产品性质

质量水平200
测定≥97.5% (acidimetric)
pH值(酸碱度)2.5-3.5 (20 ℃, 10 g/L in H2O, slurry)
mp188-190 ℃
溶解性 3.26 g/L
堆积密度630 kg/m3
储存温度2-30℃
InChI1S/C9H9NO3/c11-8(12)6-10-9(13)7-4-2-1-3-5-7/h1-5H,6H2,(H,10,13)(H,11,12)
InChI keyQIAFMBKCNZACKA-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
68069SupelcoHippuric Acidanalytical standard2327.31元/50 MG;   展开

产品说明

一般描述

Hippuric acid, the glycine conjugate of benzoic acid, is formed via a biotransformation process. From scientific literature, it is reported to be found as an excretory product in urine. Hippuric acid is also known to be catabolically synthesized from benzene-type aromatic compounds, believed to be originated from various factors such as environmental exposures, basic human liver metabolism of protein catabolism, cyclic sugar type-compounds, quinic acid, etc.

应用

Hippuric acid may be used as an analytical reference standard for the quantification of the analyte in the following:

  • Human biological fluids using high-performance liquid chromatography (HPLC) with UV detection.
  • Human and rat urine samples using gas chromatography–mass spectrometry (GC–MS).
  • Human urine samples using GC equipped with a flame ionization detector.

基本信息

线性分子式C6H5CONHCH2COOH
分子量179.17
Beilstein1073987
EC 号207-806-3
MDL编号MFCD00002692

产品性质

等级analytical standard
测定≥97.5% (GC)
保质期limited shelf life, expiry date on the label
mp187-191 ℃ (lit.)
application(s)clinical testing
格式neat
SMILES stringOC(=O)CNC(=O)c1ccccc1
InChI1S/C9H9NO3/c11-8(12)6-10-9(13)7-4-2-1-3-5-7/h1-5H,6H2,(H,10,13)(H,11,12)
InChI keyQIAFMBKCNZACKA-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
065806Fluorochem(Benzoylamino)acetic acid95%286元/100g;   1254元/500g;   9944元/5kg;   展开

基本信息

CAS Number495-69-2
MDL NumberMFCD00002692

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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