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CAS: 492-86-4
分子式: C8H7ClO3
分子量: 186.60
熔点: 116-121℃
中文名称: 
4-氯苦杏仁酸
对氯苯羟乙酸
4-氯苯乙醇酸
4-氯扁桃酸
对氯扁桃酸
对氯苯乙醇酸
对氯苦杏仁酸
2-羟基-2-对氯苯基乙酸
英文名称: 
4-chloro- alpha-hydroxy-benzeneacetic aci
4-chloromandelic acid
p-Chloromandelic acid
4-Chloro-hydroxyphenylacetic acid
p-chloro-phenylglycollic acid
(+/-)-4-chloromandelic acid
4-Chloro-DL-mandelic acid
4-Chloro-α-hydroxyphenylacetic acid
4-Chloro-à-hydroxyphenylacetic acid
性质描述: 白色或浅黄色针状结晶。熔点119-122℃。易溶于醇、醚和热苯,尚溶于水,微溶于苯和二硫化碳。
生产方法: 由氯苯与乙酐反应制得对氯苯乙酮,再经溴化、水解、酸化而得。将氯苯、二硫化碳、无水三氯化铝混合后,在搅拌下滴加乙酐,回流2h,回收二硫化碳,倒入冰冷的稀盐酸中提取苯层。依次用水、10%氢氧化钠水洗,干燥,减压蒸馏得4-氯苯乙酮。然后在36-40℃滴加溴素,再经水洗、亚硫酸氢钠洗,水洗后放置得4-ω,ω'-二溴苯乙酮结晶。加氢氧化钠液水解,最后用盐酸中和至强酸性,经乙醚提取、干燥,以苯结晶即得成品。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C838149MACKLIN4-氯扁桃酸 technical,85 %30元/5g;   75元/25g;   299元/100g;   910元/500g;   展开
储存:室温,干燥
状态:白色到几乎白色粉末到晶体
C0193TCI4-Chloro-DL-mandelic Acid>98.0%(GC)(T)385元/5G;   1800元/25G;   展开

基本信息

纯度/分析方法>98.0%(GC)(T)
分子式/分子量C8H7ClO3 = 186.59
外观与形状(20℃)固体
相关CAS RN7138-34-3
Reaxys-RN1567759
PubChem物质ID87565361
SDBS (AIST Spectral DB)4988
MDL编号MFCD00042724

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(GC)min. 98.0 %
Purity(Neutralization titration)min. 98.0 %
Melting point118.0 to 122.0 ℃

物性(参考值)

熔点120 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
250684J&K4-Chloromandelic acid98.5%187元/5g;   631元/25g;   2293元/100g;   展开

基本信息

分子式C8H7ClO3
分子量186.59
熔点115-120
MDL编码MFCD00042724
Beilstein1567759
EINECS 编号207-764-6

安全信息

图形或危害标志
提示语Warning
危险说明H302
H315
H319
H335
防范说明P261
P280
P301+P312
P302+P352
P305+P351+P338
TSCA
B24264Alfa Aesar4-Chloromandelic acid98%1162元/5g;   4693元/25g;   展开

基本信息

MDL
MFCD00042724

EINECS
207-764-6

分子式
C8H7ClO3

分子量
186.60

熔点
117-122°

灵敏度
Ambient temperatures.

形态
Powder

Beilstein
1567759

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

TSCA

CDS019939Sigma-Aldrich4-Chloromandelic acidAldrichCPR952.83元/250 MG;   展开

产品说明

其他说明

Please note that sigma-aldrich provides this product to early discovery researchers as part of a collection of unique chemicals. sigma-aldrich does not collect analytical data for this product. Buyer assumes responsibility to confirm product identity and/or purity. All sales are final.
NOTWITHSTANDING ANY CONTRARY PROVISION CONTAINED IN SIGMA-ALDRICH′S STANDARD TERMS AND CONDITIONS OF SALE OR AN AGREEMENT BETWEEN SIGMA-ALDRICH AND BUYER, SIGMA-ALDRICH SELLS THIS PRODUCT "AS-IS" AND MAKES NO REPRESENTATION OR WARRANTY WHATSOEVER WITH RESPECT TO THIS PRODUCT, INCLUDING ANY (A) WARRANTY OF MERCHANTABILITY; (B) WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE; OR (C) WARRANTY AGAINST INFRINGEMENT OF INTELLECTUAL PROPERTY RIGHTS OF A THIRD PARTY; WHETHER ARISING BY LAW, COURSE OF DEALING, COURSE OF PERFORMANCE, USAGE OF TRADE OR OTHERWISE.

基本信息

经验(实验)分子式C8H7ClO3
分子量186.59
Beilstein1567759
MDL编号MFCD00042724
PubChem化学物质编号329793316

产品性质

SMILES stringOC(C(O)=O)c1ccc(Cl)cc1
InChI1S/C8H7ClO3/c9-6-3-1-5(2-4-6)7(10)8(11)12/h1-4,7,10H,(H,11,12)
InChI keyBWSFWXSSALIZAU-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
229418Fluorochem2-(4-Chlorophenyl)-2-hydroxyacetic acid95%220元/1g;   418元/5g;   2024元/100g;   7084元/500g;   展开

基本信息

CAS Number492-86-4
MDL NumberMFCD00042724

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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