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CAS: 489-32-7
分子式: C33H40O15
分子量: 676.66
熔点: 223-225 ºC
英文名称: 
icariin
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货号品牌产品名称规格包装、参考价格
I798939MACKLIN淫羊藿提取物含10%淫羊藿苷154元/1g;   688元/5g;   咨询
储存:2-8°C
I794388MACKLIN淫羊藿提取物10mM in DMSO165元/1ml;   咨询
储存:-20°C
状态:液体
I811797MACKLIN淫羊藿苷分析对照品82元/20mg;   288元/100mg;   咨询
储存:室温
状态:微黄色到黄色粉末或晶体
I0862TCIIcariin>96.0%(HPLC)605元/200MG;   1750元/1G;   咨询

基本信息

纯度/分析方法>96.0%(HPLC)
分子式/分子量C33H40O15 = 676.67
外观与形状(20℃)固体
储存温度0-10℃
应避免的情况加热
Reaxys-RN76280
PubChem物质ID253659823
Merck Index (14)3617
MDL编号MFCD00210516

技术规格

AppearanceLight orange to Yellow to Green powder to crystal
Purity(HPLC)min. 96.0 area%
Specific rotation [a]20/D-83.0 to -90.0 deg(C=1,Pyridine)

物性(参考值)

熔点237 ℃
比旋光度 [α]D-84° (C=1,Pyridine)
最大吸收波长350(MeOH) nm

相关法规

RTECS#DJ2980500
418642J&KIcariin98%, 来源于淫羊藿171元/25MG;   564元/100MG;   咨询

基本信息

分子式C33H40O15
分子量676.66
熔点235-239
比旋光度([α]20D)-82 to -88 (C=1, Pyridine)
MDL编码MFCD00210516
Beilstein76280
Merck14,3617
存储条件Freezer -20℃

安全信息

防范说明P262
TSCA
947142J&KIcariin来源于当归, 有效含量≥90%, 可溯源至中检院标准品137元/20MG;   咨询

基本信息

分子式C33H40O15
分子量676.66
MDL编码MFCD00210516
I1286Sigma-AldrichIcariin≥94% (HPLC)1777.23元/100 MG;   9606.53元/1 G;   咨询

产品说明

一般描述

Icariin is a prenylated flavonol and the major bioactive compound found in Epimedium herb.

应用

Icariin has been used:

  • in the preparation of topical treatment to determine its effects on the improvement of cutaneous wound healing in rats
  • to test its analgesic effects on lower back pain (LBP) in rats
  • as a potential treatment in osteoporosis condition in rats
  • to study its effects on palmitate (PA)-induced insulin resistance in skeletal muscle C2C12 myotubes
  • as a neuroprotective agent to study its effects on amyloid-β (Aβ)-induced neuronal insulin resistance in human neuroblastoma SK-N-MC cells

包装

100 mg in poly bottle
1 g in poly bottle

生化/生理作用

Icariin is a potent neuroprotective agent in neurodegenerative disorders and other disorders affecting the nervous system. It elicits anti-aging properties in unfertilized oocytes against age-related damage. Icariin exerts anti-inflammatory and antifibrotic properties aiding protection in chronic kidney disease (CKD)-associated renal fibrosis in mouse model. It also serves as an excellent antidiabetic and anti-atherosclerotic agent. Icariin is an excellent anti-cancer agent.
来源于淫羊藿属植物的黄酮类葡萄糖苷。该药理活性成分或其衍生物可促进骨形成、调节多药耐药性、增强神经元活力、刺激血管生成,并表现出抗氧化活性。

基本信息

经验(实验)分子式C33H40O15
分子量676.66
MDL编号MFCD00210516
PubChem化学物质编号329815347
NACRESNA.25

产品性质

质量水平100
测定≥94% (HPLC)
颜色light yellow to yellow
溶解性DMSO: 50 mg/mL, clear, colorless to dark yellow
储存温度room temp
SMILES stringCOc1ccc(cc1)C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(=O)c4c(O)cc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(C\C=C(\C)C)c4O2
InChI1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1
InChI keyTZJALUIVHRYQQB-XLRXWWTNSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHL89714Icariinphyproof® Reference Substance4308.44元/10 MG;   咨询

产品说明

一般描述

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

生化/生理作用

来源于淫羊藿属植物的黄酮类葡萄糖苷。该药理活性成分或其衍生物可促进骨形成、调节多药耐药性、增强神经元活力、刺激血管生成,并表现出抗氧化活性。

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

基本信息

经验(实验)分子式C33H40O15
分子量676.66
MDL编号MFCD00210516

产品性质

等级primary reference standard
产品线phyproof® Reference Substance
测定≥90.0% (HPLC)
形式powder
manufacturer/tradenamePhytoLab
储存温度2-8℃
SMILES stringCOc1ccc(cc1)C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(=O)c4c(O)cc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(C\C=C(\C)C)c4O2
InChI1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1
InChI keyTZJALUIVHRYQQB-XLRXWWTNSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
56601SupelcoIcariinanalytical standard4841.68元/25 MG;   咨询

产品说明

一般描述

Icariin is a major flavonoid isolated from Epimedium spp. leaves, used as a traditional Chinese medicine to nourish the kidney and reinforce yang.

应用

Icariin has been used as a test material to investigate its, in vitro effect in promoting mouse hair follicle growth, which is assessed by vibrissae hair follicle (VHF) organ-culture model.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生化/生理作用

来源于淫羊藿属植物的黄酮类葡萄糖苷。该药理活性成分或其衍生物可促进骨形成、调节多药耐药性、增强神经元活力、刺激血管生成,并表现出抗氧化活性。

基本信息

经验(实验)分子式C33H40O15
分子量676.66
MDL编号MFCD00210516
PubChem化学物质编号329758223

产品性质

等级analytical standard
质量水平100
测定≥95% (HPLC)
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
格式neat
储存温度2-8℃
SMILES stringCOc1ccc(cc1)C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(=O)c4c(O)cc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(C\C=C(\C)C)c4O2
InChI1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1
InChI keyTZJALUIVHRYQQB-XLRXWWTNSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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