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CAS: 486-66-8
分子式: C15H10O4
分子量: 254.24
熔点: 315-323°C (dec.)
中文名称: 
7-羟基-3-(4-羟苯基)-4-苯并吡喃酮
黄豆苷原
大豆黄素
大豆异黄酮
大豆素
大豆黄酮
黄豆甙元
英文名称: 
7-Hydroxy-3-(4-hydroxyphenyl)-4-benzopyrone
7-hydroxy-3-(4-hydroxyphenyl)-4h-1-benzopyran-4-on
4',7-dihydroxyisoflavone
7,4'-dihydroxyisoflavone
7-hydroxy-3-(4-hydroxyphenyl)-4h-1-benzopyran-4-one
daidzein
daidzeol
4',7-dihydroxy-isoflavon
k 251b
4',7-Dihydroxy­iso­flavone
Soy flavone
展开更多英文名
用途: 血管扩张药。
推荐供应商
货号品牌产品名称规格包装、参考价格
D807010MACKLIN黄豆苷原分析对照品,≥98%88元/20mg;   咨询
储存:2-8℃
状态:类白色至黄色粉末
D794527MACKLIN黄豆苷原10mM in DMSO100元/1ml;   300元/5ml;   咨询
储存:-20°C
状态:液体
D807011MACKLIN黄豆苷原97%28元/1g;   33元/5g;   56元/25g;   152元/100g;   715元/500g;   咨询
储存:2-8℃
状态:类白色至黄色粉末
D2668TCIDaidzein>98.0%(T)(HPLC)255元/1G;   咨询

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C15H10O4 = 254.24
外观与形状(20℃)固体
Reaxys-RN231523
PubChem物质ID87569086
Merck Index (14)2801
MDL编号MFCD00016954

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#DJ3100040
160696J&KDaidzein98%132元/100mg;   189元/1G;   935元/5G;   咨询

基本信息

分子式C15H10O4
分子量254.24
熔点>290
MDL编码MFCD00016954
Beilstein231523
Merck14,2801
EINECS 编号207-635-4
存储条件Freezer -20℃

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
防范说明P305+P351+P338
WGK3
RTECSDJ3100040
TSCA
981203J&KDaidzein来源于大豆, 有效含量≥90%, 可溯源至中检院标准品91元/20MG;   咨询

基本信息

分子式C15H10O4
分子量254.24
MDL编码MFCD00016954
B22877Alfa Aesar4',7-Dihydroxyisoflavone97%1635元/1g;   3502元/5g;   13521元/25g;   咨询

应用
4',7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.

备注
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.

基本信息

MDL
MFCD00016954

EINECS
207-635-4

分子式
C15H10O4

分子量
254.24

熔点
328-332° dec.

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Insoluble in water. Soluble in DMSO (25 mg/ml), ethanol (2 mg/ml), DMF (10 mg/ml), and 1:10 DMSO:PBS (pH 7.2) (0.15 mg/ml).

Beilstein
231523

Merck
14,2801

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

RTECS
DJ3100040

TSCA

C32823Alfa AesarDaidzein98%1330元/25mg;   4785元/100mg;   咨询

基本信息

Ref#
32823

MDL
16954

分子式
C15 H10 O4

分子量
254.24

形态
White powder

05340590Daidzeinprimary reference standard5592.1元/50 MG;   咨询

产品说明

一般描述

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

应用

草药产品分析的标准品。

生化/生理作用

大豆异黄酮对二甲基苯并蒽 (DMBA) 诱导的肝细胞氧化损伤有保护作用。DMBA 下调的过氧化氢酶和超氧化物歧化酶活性可被大豆苷元恢复。

基本信息

经验(实验)分子式C15H10O4
分子量254.24
Beilstein231523
EC 号207-635-4
MDL编号MFCD00016954
PubChem化学物质编号329747692
NACRESNA.24

产品性质

等级primary reference standard
保质期limited shelf life, expiry date on the label
manufacturer/tradenameHWI
application(s)food and beverages
SMILES stringOc1ccc(cc1)C2=COc3cc(O)ccc3C2=O
InChI1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
InChI keyZQSIJRDFPHDXIC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
D7802Sigma-AldrichDaidzein≥98%, synthetic1446.35元/25 MG;   4738.66元/100 MG;   咨询

产品说明

一般描述

大豆苷元是一种存在于大豆中的异黄酮。它调节氧化应激、血管新生、细胞生长和凋亡。大豆苷元具有抗氧化、抗雌激素和抗动脉粥样硬化作用。它可提供抗骨质疏松保护。

应用

大豆苷元已用于:

  • 作为评估大鼠生育力的对照
  • 研究其对卵巢癌的影响
  • 体外模拟抗氧化活性

包装

25 mg in poly bottle
100 mg in glass bottle
在氩气下包装。

生化/生理作用

大豆异黄酮对二甲基苯并蒽 (DMBA) 诱导的肝细胞氧化损伤有保护作用。DMBA 下调的过氧化氢酶和超氧化物歧化酶活性可被大豆苷元恢复。
大豆黄酮是一种植物雌激素,被认为在预防激素诱导的癌症方面起作用。在瑞士 3T3 细胞中阻滞细胞周期G1

基本信息

经验(实验)分子式C15H10O4
分子量254.24
Beilstein231523
EC 号207-635-4
MDL编号MFCD00016954
PubChem化学物质编号24278030
NACRESNA.77

产品性质

质量水平200
生物来源synthetic
测定≥98%
形式powder
mp>290  ℃
溶解性DMSO: 10 mg/mL
储存温度−20℃
SMILES stringOc1ccc(cc1)C2=COc3cc(O)ccc3C2=O
InChI1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
InChI keyZQSIJRDFPHDXIC-UHFFFAOYSA-N
Gene Informationhuman ... ESR1(2099), ESR2(2100), UGT1A4(54657)
mouse ... Aldh1a2(19378), Hexa(15211), Maoa(17161)
rat ... Aldh1a2(116676)

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
16587SupelcoDaidzeinanalytical standard3274.25元/10 MG;   咨询

产品说明

一般描述

大豆黄酮是一种具有内分泌活性的雌激素异黄酮。该植物雌激素能够与雌激素结合以在体内发挥雌激素作用。它天然存在于大豆种子和面粉中。

应用

关于适当的仪器技术的更多信息,请参见产品的检验报告。联系技术服务部寻求进一步支持。
以大豆苷元为标准品,采用管中固相微萃取-高效液相色谱法 (in-tube SPME-HPLC) 测定大豆食品中的大豆苷元和染料木素。还使用高效液相色谱 –UV– 电喷雾电离-质谱检测器 (HPLC–UV–ESI-MSD) 作为参比标准品测定红三叶草中的异黄酮。

包装

10 mg in glass bottle
无底玻璃瓶。内含物装在插入的融合锥内。

生化/生理作用

大豆异黄酮对二甲基苯并蒽 (DMBA) 诱导的肝细胞氧化损伤有保护作用。DMBA 下调的过氧化氢酶和超氧化物歧化酶活性可被大豆苷元恢复。

基本信息

经验(实验)分子式C15H10O4
分子量254.24
Beilstein231523
EC 号207-635-4
MDL编号MFCD00016954
PubChem化学物质编号329751271
NACRESNA.24

产品性质

等级analytical standard
质量水平100
测定≥97.0% (HPLC)
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)food and beverages
格式neat
储存温度2-8℃
SMILES stringOc1ccc(cc1)C2=COc3cc(O)ccc3C2=O
InChI1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
InChI keyZQSIJRDFPHDXIC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHR1858SupelcoDaidzeinPharmaceutical Secondary Standard; Certified Reference Material2391.32元/100 MG;   咨询

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

生化/生理作用

大豆异黄酮对二甲基苯并蒽 (DMBA) 诱导的肝细胞氧化损伤有保护作用。DMBA 下调的过氧化氢酶和超氧化物歧化酶活性可被大豆苷元恢复。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAB0087 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C15H10O4
分子量254.24
Beilstein231523
EC 号207-635-4
MDL编号MFCD00016954

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
形式powder
CofAcurrent certificate can be downloaded
包装package of 100 mg
application(s)pharmaceutical
药典可追溯性traceable to USP 1162421
储存温度-10 to -25℃
SMILES stringOc1ccc(cc1)C2=COc3cc(O)ccc3C2=O
InChI1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
InChI keyZQSIJRDFPHDXIC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHL89181Daidzeinphyproof® Reference Substance4533.11元/50 MG;   咨询

产品说明

一般描述

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

生化/生理作用

大豆异黄酮对二甲基苯并蒽 (DMBA) 诱导的肝细胞氧化损伤有保护作用。DMBA 下调的过氧化氢酶和超氧化物歧化酶活性可被大豆苷元恢复。

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

基本信息

经验(实验)分子式C15H10O4
分子量254.24
Beilstein231523
MDL编号MFCD00016954

产品性质

等级primary reference standard
产品线phyproof® Reference Substance
测定≥95.0% (HPLC)
形式powder
manufacturer/tradenamePhytoLab
储存温度2-8℃
SMILES stringOc1ccc(cc1)C2=COc3cc(O)ccc3C2=O
InChI1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
InChI keyZQSIJRDFPHDXIC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1162421USPDaidzeinUnited States Pharmacopeia (USP) Reference Standard2914.43元/25 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

大豆异黄酮对二甲基苯并蒽 (DMBA) 诱导的肝细胞氧化损伤有保护作用。DMBA 下调的过氧化氢酶和超氧化物歧化酶活性可被大豆苷元恢复。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C15H10O4
分子量254.24
Beilstein231523
MDL编号MFCD00016954
PubChem化学物质编号329749508
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
储存温度−20℃
SMILES stringOc1ccc(cc1)C2=COc3cc(O)ccc3C2=O
InChI1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
InChI keyZQSIJRDFPHDXIC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
251600Sigma-AldrichDaidzein-CAS 486-66-8-CalbiochemInactive analog of Genistein.1164.01元/25 MG;   咨询

产品说明

一般描述

Inactive analog of Genistein (Cat. No. 345834). Blocks the G1 phase of the cell cycle in Swiss/3T3 cells by inhibiting casein kinase II activity. Inhibits the growth of MiaPaC-2 and PANC-1 cells (IC50= 45 µM and 75 µM, respectively).
Inactive analog of genistein (Cat. No. 345834). Blocks the G1 phase of the cell cycle in Swiss 3T3 cells by inhibiting casein kinase II activity. Inhibits epidermal growth factor (EGF) receptor autophosphorylation (IC50 >300 µM). Inhibits the growth of MiaPaC-2 and PANC-1 cells (IC50= 45 µM and 75 µM, respectively).

包装

25 mg in Plastic ampoule
Packaged under inert gas

生化/生理作用

Target IC50: 45 µM, 75 µM for inhibiting the growth of MiaPaC-2 and PANC-1 cells, respectively
Primary Target
MiaPaC-2, PANC-1
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Irritant (B)

重悬

Following reconstitution, aliquot and freeze (-20°C) under an inert gas. DMSO stock solutions are stable for up to 2 months at -20°C.

其他说明

Guo, J-M., et al. 2004. World J. Gastroenterol.10, 860.
Higashi, K., and Ogawara, H. 1994. Biochim. Biophys. Acta 1221, 29.
Lavens, S.E., et al. 1992. Am. J. Respir. Cell Mol. Biol.7, 637.
Akiyama, T., et al. 1987. J. Biol. Chem.262, 5592.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C15H10O4
分子量254.24
MDL编号MFCD00016954

产品性质

质量水平100
测定≥98% (TLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
颜色 off-white
溶解性DMSO: 200 mg/mL
运输ambient
储存温度−20℃
InChI1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
InChI keyZQSIJRDFPHDXIC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
024979Fluorochem7-Hydroxy-3-(4-hydroxy-phenyl)-chromen-4-one98%220元/1g;   352元/10g;   726元/25g;   1958元/100g;   咨询

基本信息

CAS Number486-66-8
MDL NumberMFCD00016954

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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