CAS 484-17-3; 9-羟基菲; 9-phenanthrol

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货号

品牌

产品名称

规格

包装、参考价格

P792765

MACKLIN

9-菲酚

10mM in DMSO

720元/1ml;

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储存：-20°C

P857354

MACKLIN

9-菲酚

97%

160元/250mg; 433元/1g; 1795元/5g; 6418元/25g;

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储存：室温,干燥
状态：棕色固体

211281

Sigma-Aldrich

9-Phenanthrol

technical grade

1535.82元/1 G; 4027.58元/5 G;

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产品说明

应用

9-菲咯尔被用来研究单壁碳纳米管的 ck-edge 和 ok-edge 近边 X 射线吸收精细结构 (NEXAFS) 光谱。

包装

1, 5 g in glass bottle

生化/生理作用

9-邻菲罗是瞬时受体电位美拉斯汀 4 (TRPM) 通道的抑制剂，TRPM 通道是一种 Ca²⁺ 激活的非选择性阳离子通道。

基本信息

经验(实验)分子式	C₁₄H₁₀O
分子量	194.23
EC 号	207-602-4
MDL编号	MFCD00082298
PubChem化学物质编号	24852666
NACRES	NA.22

产品性质

等级	technical grade
mp	139-143 ℃ (lit.)
SMILES string	Oc1cc2ccccc2c3ccccc13
InChI	1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H
InChI key	DZKIUEHLEXLYKM-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

648492

Sigma-Aldrich

TRPM4 inhibitor, 9-Phenanthrol-CAS 484-17-3-Calbiochem

The TRPM4 inhibitor, 9-Phenanthrol, also referenced under CAS 484-17-3, controls the biological activity of TRPM4. This small molecule/inhibitor is primarily used for Biochemicals applications.

1113.94元/50 MG;

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产品说明

一般描述

A cell permeable hydroxytricyclic derivative that acts as a specific and reversible inhibitor of transient receptor potential melastatin 4 (TRPM4) (IC₅₀ = 20 µM in HEK293 cells). Does not affect TRPM5 and cystic fibrosis transmembrane conductance regulators (CFTR) channels. Decreases the occurrence of early after depolarizations (EAD) and exhibits an anti-arrhythmic effect that is independent of the action of protein kinase A. Shown to abolish NMDA-induced burst firing in dopaminergic neurons. Does not affect K+ currents at ~10 µM, but at higher concentration (~100 µM) it reversibly reduces K+ currents.

包装

50 mg in Glass bottle
Packaged under inert gas

警告

Toxicity: Irritant (B)

重悬

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

其他说明

Grand, T., et al. 2008. Brit. Journ. Pharm.153, 1697.
Simard, C., 2012. Brit. Journ. Pharm.165, 2354.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₁₄H₁₀O
分子量	194.23
MDL编号	MFCD00082298

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze protect from light
颜色	brown
溶解性	DMSO: 50 mg/mL
运输	wet ice
储存温度	2-8℃
InChI	1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H
InChI key	DZKIUEHLEXLYKM-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

226442

Fluorochem

Phenanthren-9-ol

95%

1298元/250mg; 3080元/1g; 10824元/5g;

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基本信息

CAS Number	484-17-3
MDL Number	MFCD00082298
Melting Point	139-143℃

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .