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CAS: 478-43-3
分子式: C15H8O6
分子量: 284.22
熔点: 321-322℃
英文名称: 
9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic aci
9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroic aci
9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid
cassic acid
chrysazin-3-carboxylic acid
monorhein
rheic acid
rhein
rhubarb yellow
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货号品牌产品名称规格包装、参考价格
R817293MACKLIN大黄酸分析标准品,≥98%154元/20mg;   咨询
储存:2~8°C
状态:黄色到橙色固体,粉末或晶体
R817294MACKLIN大黄酸98%26元/10mg;   29元/50mg;   79元/1g;   224元/5g;   622元/25g;   2403元/100g;   咨询
储存:2~8°C
状态:黄色到橙色固体,粉末或晶体
R796955MACKLIN大黄酸10mM in DMSO256元/1ml;   咨询
储存:-20°C
D3986TCI4,5-Dihydroxyanthraquinone-2-carboxylic Acid>95.0%(T)(HPLC)290元/200MG;   990元/1G;   咨询

基本信息

纯度/分析方法>95.0%(T)(HPLC)
分子式/分子量C15H8O6 = 284.22
外观与形状(20℃)固体
Reaxys-RN2222155
PubChem物质ID125307728
Merck Index (14)8176
MDL编号MFCD00009618

技术规格

AppearanceLight yellow to Brown powder to crystal
Purity(HPLC)min. 95.0 area%
Purity(Neutralization titration)min. 95.0 %

物性(参考值)

熔点321 ℃
最大吸收波长432(MeOH) nm

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#CA9516000
951089J&KRhein98.5%348元/50MG;   1037元/250MG;   3423元/1G;   咨询

基本信息

分子式C15H8O6
分子量284.22
熔点≥300
MDL编码MFCD00009618
Beilstein2222155
EINECS 编号207-521-4
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK2
RTECSCA9516000
TSCA
948452J&KRhein来源于大黄, 有效含量≥85%, 可溯源至中检院标准品148元/20MG;   咨询

基本信息

分子式C15H8O6
分子量284.22
MDL编码MFCD00009618
H60902Alfa AesarRhein97%7781元/250mg;   咨询

应用
Rhein is used to inhibit growth factor beta-1 induced plasminogen activator inhibitor-1 in endothelial cells. It acts as an antibacterial agent against Staphylococcus aureus. It is also used as a laxative. Further, it is employed as a pharmaceutical intermediate.

备注
Incompatible with oxidizing agents. Heat sensitive.

基本信息

MDL
MFCD00009618

EINECS
207-521-4

分子式
C15H8O6

分子量
284.22

熔点
>300°

灵敏度
Keep Cold.

形态
Powder

溶解性
Soluble in sodium hydroxide. Insoluble in water, dimethylsulfoxide and ethanol.

Beilstein
2222155

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

RTECS
CA9516000

TSCA

275611Sigma-AldrichRheintechnical grade1301.64元/50 MG;   1460.51元/250 MG;   咨询

产品说明

一般描述

The pharmakokinetics of Rhein was studied.

应用

Rhein was used to induce necrosis-apoptosis switch in injured pancreatic acinar cells.

包装

50, 250 mg in glass bottle

基本信息

经验(实验)分子式C15H8O6
分子量284.22
Beilstein2222155
EC 号207-521-4
MDL编号MFCD00009618
PubChem化学物质编号24856659
NACRESNA.22

产品性质

等级technical grade
质量水平100
mp≥300 ℃ (lit.)
SMILES stringOC(=O)c1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
InChI1S/C15H8O6/c16-9-3-1-2-7-11(9)14(19)12-8(13(7)18)4-6(15(20)21)5-10(12)17/h1-5,16-17H,(H,20,21)
InChI keyFCDLCPWAQCPTKC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 2
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
R7269Sigma-AldrichRhein2410.17元/10 MG;   9087.77元/50 MG;   咨询

产品说明

包装

10, 50 mg in glass insert

生化/生理作用

具有抗炎、抗骨关节炎和抗癌活性并富含于大黄中的成分。它可降低IL-1β的产生和分泌、半胱天冬酶-3的活性、诱导型一氧化氮合酶活性以及c-Jun和c-Jun NH2-末端激酶(JNK)的磷酸化。

基本信息

经验(实验)分子式C15H8O6
分子量284.22
Beilstein2222155
EC 号207-521-4
MDL编号MFCD00009618
PubChem化学物质编号24899390
NACRESNA.77

产品性质

质量水平100
mp≥300 ℃ (lit.)
储存温度2-8℃
SMILES stringOC(=O)c1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
InChI1S/C15H8O6/c16-9-3-1-2-7-11(9)14(19)12-8(13(7)18)4-6(15(20)21)5-10(12)17/h1-5,16-17H,(H,20,21)
InChI keyFCDLCPWAQCPTKC-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
Y0002159RheinCRS, European Pharmacopoeia (EP) Reference Standard1523.69元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C15H8O6
分子量284.22
Beilstein2222155
MDL编号MFCD00009618

产品性质

manufacturer/tradenameEDQM
mp≥300 ℃ (lit.)
储存温度2-8℃
SMILES stringOC(=O)c1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
InChI1S/C15H8O6/c16-9-3-1-2-7-11(9)14(19)12-8(13(7)18)4-6(15(20)21)5-10(12)17/h1-5,16-17H,(H,20,21)
InChI keyFCDLCPWAQCPTKC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 2
30873SupelcoRheinanalytical standard5039.21元/10 MG;   咨询

产品说明

一般描述

Rhein is an active component of rhubarb (Rheum officinale), a medicinal herb in traditional Chinese medicine (TCM). It is known to exhibit antibacterial and anti-inflammatory activities.

应用

Rhein may be used as an analytical reference standard for the determination of the analyte in rat plasma and rhubarb roots, dock flowers and senna leaves by column-switching high-performance liquid chromatography and normal-phase high performance liquid chromatography, respectively.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

基本信息

经验(实验)分子式C15H8O6
分子量284.22
Beilstein2222155
EC 号207-521-4
MDL编号MFCD00009618
PubChem化学物质编号329753592
NACRESNA.24

产品性质

质量水平100
等级analytical standard
测定≥95.0% (HPLC)
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
杂质≤5.0% water
mp≥300 ℃ (lit.)
application(s)food and beverages
格式neat
SMILES stringOC(=O)c1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
InChI1S/C15H8O6/c16-9-3-1-2-7-11(9)14(19)12-8(13(7)18)4-6(15(20)21)5-10(12)17/h1-5,16-17H,(H,20,21)
InChI keyFCDLCPWAQCPTKC-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
PHL89385Rheinphyproof® Reference Substance3997.36元/20 MG;   咨询

产品说明

一般描述

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

基本信息

经验(实验)分子式C15H8O6
分子量284.22
Beilstein2222155
MDL编号MFCD00009618

产品性质

等级primary reference standard
产品线phyproof® Reference Substance
测定≥95.0% (HPLC)
manufacturer/tradenamePhytoLab
mp≥300 ℃ (lit.)
application(s)food and beverages
格式neat
SMILES stringOC(=O)c1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
InChI1S/C15H8O6/c16-9-3-1-2-7-11(9)14(19)12-8(13(7)18)4-6(15(20)21)5-10(12)17/h1-5,16-17H,(H,20,21)
InChI keyFCDLCPWAQCPTKC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P280 - P280 - P304 + P340 + P312 - P337 + P313
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 2
049599Fluorochem1,8-Dihydroxy-3-carboxyanthraquinone95%1078元/5g;   1782元/10g;   2684元/25g;   6424元/100g;   咨询

基本信息

CAS Number478-43-3
MDL NumberMFCD00009618

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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