CAS 476-66-4; 2,3,7,8-四羟基-[1]-苯并吡喃并[5,4,3-CDE][1]苯并吡喃-5,10-二酮; [1]-Benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione,2,3,7,8-tetrahydroxy-

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E832096

MACKLIN

鞣花酸

分析对照品

168元/20mg;

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储存：2~8°C,密封
状态：奶油色到棕色粉末

E997296

MACKLIN

鞣花酸

98%,来源于石榴树皮

93元/5g; 255元/25g; 876元/100g; 3888元/500g;

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储存：室温
状态：白色到黄色和白色到棕色和非常暗米黄色粉末或晶体

E875682

MACKLIN

鞣花酸

90%，来源于石榴

49元/5g; 183元/25g; 720元/100g; 3160元/500g;

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储存：室温
状态：黄色到灰色到棕色粉末

E875680

MACKLIN

鞣花酸

90%，来源于五倍子

48元/5g; 180元/25g; 715元/100g; 2926元/500g;

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储存：室温
状态：黄色到灰色到棕色粉末

成型收缩率	0.7%
拉伸强度（20℃）	100 Mpa
伸长率	8%
弯曲强度（20℃）	130 Mpa
压缩强度（20℃）	140 Mpa
简支梁冲击强度（无缺口）	100 kJ/m²
Tg(N₂,10℃/min)	256 ℃
Td⁵(Air,10℃/min)	510 ℃
HDT(1.82Mpa,N₂,10℃/min)	240 ℃
热膨胀系数	5.0×10^-5/℃
介电强度	200 Kv/mm
介电常数（1MHz,20℃)	3.2
介质损耗（1MHz,20℃)	2.0×10^-3
表面电阻率	10¹⁴Ω
体积电阻率	10¹⁶Ω·cm

E808704

MACKLIN

鞣花酸

98%

40元/1g; 82元/5g; 197元/25g; 771元/100g; 3650元/500g;

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储存：室温
状态：奶油色到黄色到灰色到棕色粉末

247473

J&K

Ellagic acid

98%, 来源于五倍子的种子

1080元/50G; 1777元/250G; 3593元/1KG;

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基本信息

分子式	C₁₄H₆O₈
分子量	302.19
熔点	300
MDL编码	MFCD00006914
Beilstein	47549
Merck	14,3547
EINECS 编号	207-508-3

安全信息

图形或危害标志
提示语	Warning
危险说明	H315 H319 H335
防范说明	P261 P305+P351+P338
WGK	1
RTECS	DJ2620000
TSCA	否

941975

J&K

Ellagic acid

95%

99元/5G; 328元/25G; 1049元/100G;

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基本信息

分子式	C₁₄H₆O₈
分子量	302.19
熔点	300
MDL编码	MFCD00006914
Beilstein	47549
Merck	14,3547
EINECS 编号	207-508-3

安全信息

图形或危害标志
提示语	Warning
危险说明	H302
防范说明	P305+P351+P338
WGK	1
RTECS	DJ2620000
TSCA	否

995625

J&K

Ellagicacid

171元/20MG;

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基本信息

分子式	C₁₄H₆O₈
分子量	302.19
MDL编码	MFCD00006914

A15722

Alfa Aesar

Ellagic acid hydrate

97%, may cont. up to 12% water

586元/5g; 2322元/25g; 7441元/100g;

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应用
Ellagic acid used as selective, ATP-competitive inhibitor of casein kinase 2. Exhibits antitumor activity and inhibits glutathione S-transferase. It is also used as a Topo I and II, FGR, GSK, and PKA inhibitor.Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma.Contact activation in blood coagulation.

备注
Air sensitive and light sensitive. Store under dry inert gas. Store in cool dry place in tightly closed container. Store in dark and away form air.

基本信息

MDL
MFCD00149494

EINECS
207-508-3

分子式
C₁₄H₆O₈?xH₂O

分子量
302.20(anhy)

熔点
450° dec.

灵敏度
Air Sensitive. Light Sensitive. Ambient temperatures.

形态
Powder

溶解性
Slightly soluble in water. Soluble in 1M sodium hydroxide (10 mg/ml), EtOH, and pyridine.

Beilstein
47549

Merck
14,3547

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

RTECS
DJ2620000

TSCA
否

C11774

Alfa Aesar

Ellagic acid

97%

819元/2.5g; 2216元/10g; 7166元/50g;

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基本信息

Ref#
11774

MDL
6914

分子式
C14 H6 O8

分子量
302.19

形态
Cream to brown powder

E2250

Sigma-Aldrich

Ellagic acid

≥95% (HPLC), powder, from tree bark

1867.95元/1 G; 7453.94元/5 G; 11189.8元/10 G;

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产品说明

一般描述

鞣花酸是在多种水果和蔬菜中天然生成的酚酸类次级植物代谢物，通常存在于绿茶、石榴、草莓、树莓和核桃中。

应用

鞣花酸已用于：

基于植物乳杆菌CECT 748T研究酚酸类膳食物质的代谢机制
作为植物乳杆菌单宁酶高产的潜在底物
在荨麻酚类成分和抗氧剂活性研究中作为检测标准品
研究膳食鞣花酸和脂肪形成表观遗传调节之间的关系

包装

1, 5, 10 g in poly bottle

生化/生理作用

研究发现，鞣花酸可抑制低密度脂蛋白的氧化，因这种抗氧化活性它对人心脏具有保护作用。此外，它也具有抗癌、抗纤维化、抗疟原虫、细胞凋亡和化学预防活性。
其是一种常见的植物多酚，是谷胱甘肽S-转移酶的抑制剂。可用于血浆中XIIa因子的测定。可在血液凝固中发生接触激活。

基本信息

经验(实验)分子式	C₁₄H₆O₈
分子量	302.19
Beilstein	47549
EC 号	207-508-3
MDL编号	MFCD00006914
PubChem化学物质编号	24894460
NACRES	NA.77

产品性质

生物来源	tree bark
质量水平	200
测定	≥95% (HPLC)
形式	powder
保质期	5 yr
溶解性	1 M NaOH: 10 mg/mL
SMILES string	Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2-c34
InChI	1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H
InChI key	AFSDNFLWKVMVRB-UHFFFAOYSA-N
Gene Information	human ... CSK(1445), DYRK1A(1859), GSK3B(2932), SRC(6714) rat ... Lyn(81515), Syk(25155)

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

PHL89653

Ellagic acid

phyproof^® Reference Substance

3461.57元/50 MG;

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产品说明

一般描述

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

生化/生理作用

其是一种常见的植物多酚，是谷胱甘肽S-转移酶的抑制剂。可用于血浆中XIIa因子的测定。可在血液凝固中发生接触激活。

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

基本信息

经验(实验)分子式	C₁₄H₆O₈
分子量	302.19
Beilstein	47549
MDL编号	MFCD00006914

产品性质

等级	primary reference standard
产品线	phyproof^® Reference Substance
测定	≥98.0% (HPLC)
形式	powder
manufacturer/tradename	PhytoLab
SMILES string	Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2-c34
InChI	1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H
InChI key	AFSDNFLWKVMVRB-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable

14668

Supelco

Ellagic acid

analytical standard

1898.39元/50 MG;

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产品说明

一般描述

鞣花酸是没食子酸的二聚衍生物。它是一种植物多酚，具有抗氧化，抗炎，抗癌和抗动脉粥样硬化的属性。

应用

采用鞣花酸薄层层析和反相高效液相色谱法测定了木贼根皮中植物成分的含量。
有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务部门。

生化/生理作用

其是一种常见的植物多酚，是谷胱甘肽S-转移酶的抑制剂。可用于血浆中XIIa因子的测定。可在血液凝固中发生接触激活。

包装

无底玻璃瓶。内含物装在插入的融合锥内。

基本信息

经验(实验)分子式	C₁₄H₆O₈
分子量	302.19
Beilstein	47549
EC 号	207-508-3
MDL编号	MFCD00006914
PubChem化学物质编号	329750574
NACRES	NA.24

产品性质

质量水平	100
等级	analytical standard
测定	≥95.0% (HPLC)
保质期	limited shelf life, expiry date on the label
technique(s)	HPLC: suitable gas chromatography (GC): suitable
杂质	≤12% water
application(s)	food and beverages
格式	neat
储存温度	2-8℃
SMILES string	Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2-c34
InChI	1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H
InChI key	AFSDNFLWKVMVRB-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable

324683

Sigma-Aldrich

Ellagic Acid, Dihydrate-CAS 476-66-4-Calbiochem

A cell-permeable, reversible, potent antioxidant that has anti-mutagenic and anti-carcinogenic properties.

1364.79元/500 MG;

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产品说明

一般描述

A cell-permeable, reversible, and potent antioxidant that has anti-mutagenic and anti-carcinogenic properties. Acts as a selective and ATP-competitive inhibitor of CK2 (IC₅₀ = 40 nM). Moderately inhibits DNA topoisomerases I and II, Lyn, PKA catalytic subunit, Lyk, GSK-3, PKC, and FGR (IC₅₀ = 1.8, 2.1, 2.9, 3.5, 4.3, 7.5, 8.0, and 9.4 µM, respectively). Only minimally inhibits DYRK1a, CSK, RET, Flt3, and NPM-ALK (IC₅₀ >40 µM). Shown to act as an uncompetitive inhibitor of arginine methyltransferase CARM1 and block histone H3R17 methylation.
A cell-permeable, reversible, potent antioxidant that has anti-mutagenic and anti-carcinogenic properties. Acts as a selective and ATP-competitive inhibitor of CK2 (IC₅₀ = 40 nM). Moderately inhibits DNA topoisomerases I and II, Lyn, PKA catalytic subunit, Lyk, GSK-3, PKC, and FGR (IC₅₀ = 1.8, 2.1, 2.9, 3.5, 4.3, 7.5, 8.0, and 9.4 µM, respectively). Only minimally inhibits DYRK1a, CSK, RET, Flt3, and NPM-ALK (IC₅₀ >40 µM). Shown to act as an uncompetitive inhibitor of arginine methyltransferase CARM1 and block histone H3R17 methylation.

包装

500 mg in Glass bottle
Packaged under inert gas

生化/生理作用

Primary Target
CDK2
Target IC₅₀: 40 nM against CK2; 1.8, 2.1, 2.9, 3.5, 4.3, 7.5, 8.0, and 9.4 µM, against DNA topoisomerases I and II, Lyn, PKA catalytic subunit, Lyk, GSK-3, PKC, and FGR, respectively
Reversible: yes
Cell permeable: yes
Product competes with ATP.

警告

Toxicity: Irritant (B)

制备说明

For complete solubilization in ethanol, slight heating may be required.

重悬

Following reconstitution, aliquot and freeze (-20°C). Ethanol stock solutions are stable for up to 1 week at -20°C. Alkaline solutions are unstable and should be prepared just prior to use.

其他说明

Selvi, B.R., et al. 2009, J. Biol. Chem. In press.
Cozza, G., et al. 2006. J. Med. Chem.49, 2363.
Wang, B.H., et al. 1998. Planta Med. 64, 195.
Constantinou, A., et al. 1995. Nutr. Cancer23, 121.
Hickey, M.J., et al. 1995. Biochem. Soc. Trans.23, 607s.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₁₄H₆O₈ · 2H₂O
分子量	338.22
MDL编号	MFCD00006914

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze protect from light
颜色	slightly beige
溶解性	1 M NaOH: 10 mg/mL ethanol: 10 mg/mL
运输	ambient
储存温度	10-30℃
InChI	1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H
InChI key	AFSDNFLWKVMVRB-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable

387721

Fluorochem

Ellagic acid

98%

308元/5g; 770元/10g; 1430元/25g; 4620元/100g;

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基本信息

CAS Number	476-66-4
MDL Number	MFCD00006914

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .