| CAS: | 475488-23-4 | |
| 分子式: | C28H31N5O | |
| 分子量: | 453.58 | |
| 英文名称: |
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| 用途: | NVP-ADW742是一种IGF-1R抑制剂，IC50为0.17 μM，作用于IGF-1R比作用于InsR效果强16倍以上；对HER2， PDGFR， VEGFR-2， Bcr-Abl和c-Kit几乎没有活性。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||
| N864488 | MACKLIN | NVP-ADW742 | ≥99% | 929元/5mg; | 咨询 | ||||||||||||||||||||||||||||
储存：-20°C | |||||||||||||||||||||||||||||||||
| N797214 | MACKLIN | NVP-ADW742 | 10mM in DMSO | 868元/1ml; | 咨询 | ||||||||||||||||||||||||||||
储存：-20°C | |||||||||||||||||||||||||||||||||
| SML1921 | Sigma-Aldrich | NVP-ADW742 | ≥98% (HPLC) | 1396.09元/5 MG; 4498.97元/25 MG; | 咨询 | ||||||||||||||||||||||||||||
产品说明 应用 NVP-ADW742 has been used as an insulin-like growth factor 1 receptor (IGF1R) inhibitor to test the effects of filamin A (FLNA) silencing in a cell proliferation assay. 生化/生理作用 NVP-ADW742 is a potent and selective ATP-competitive inhibitor of Insulin-like growth factor-I receptor (IGF-IR) kinase. NVP-ADW742 sensitizes cancer cell lines to multiple anticancer agents including etoposide, carboplatin, imatinib, vincristine, and doxorubicin. 基本信息
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