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CAS: 472-15-1
分子式: C30H48O3
分子量: 456.70
熔点: 295-298℃
中文名称: 
白桦脂酸
桦木酸
英文名称: 
Betulinic acid
3β-Hydroxy-20(29)-lupaene-28-oic acid
3beta-Hydroxy-20(29)-lupaene-28-oic Acid
推荐供应商
货号品牌产品名称规格包装、参考价格
B796903MACKLIN白桦脂酸10mM in DMSO463元/1ml;   咨询
储存:-20°C
B801934MACKLIN白桦脂酸分析对照品280元/20mg;   咨询
储存:2~8°C
折射率:7.8 ° (C=0.9, Pyridine)
B804029MACKLIN白桦脂酸97%30元/100mg;   80元/500mg;   123元/1g;   498元/5g;   1998元/25g;   7706元/100g;   咨询
储存:2~8°C
状态:白色到灰白色粉末
折射率:7.8 ° (C=0.9, Pyridine)
B2836TCIBetulinic Acid>97.0%(GC)(T)590元/100MG;   3750元/1G;   咨询

基本信息

纯度/分析方法>97.0%(GC)(T)
分子式/分子量C30H48O3 = 456.71
外观与形状(20℃)固体
Reaxys-RN2824245
PubChem物质ID87558736
Merck Index (14)1190

技术规格

AppearanceWhite to Light yellow to Light orange powder to crystal
Purity(GC)min. 97.0 %
Purity(Neutralization titration)min. 97.0 %(after drying)
Specific rotation [a]20/D+6.0 to +10.0 deg(C=0.9, pyridine)
Drying lossmax. 5.0 %

物性(参考值)

熔点294 ℃
比旋光度 [α]D7.8° (C=0.9,Pyridine)
水溶性实际上不溶
溶解性(可溶于)氯仿,乙醚,甲醇,乙醇,丙酮
溶解度(极微溶)

安全信息

危险性说明H413 : 可能对水生生物造成长期持续有害影响。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P273 : 避免释放到环境中。
119165J&KBetulinic Acid98%393元/50MG;   1567元/250MG;   3563元/1G;   咨询

基本信息

分子式C30H48O3
分子量456.70
熔点295-298
MDL编码MFCD00009619
Beilstein2824245
Merck14,1190
EINECS 编号207-448-8

安全信息

防范说明P262
WGK3
962655J&KBetulinicacid, for identification, from Birch bark, NIFDC traceable用于鉴别, 来源于白桦皮, 可溯源至中检院标准品228元/20MG;   咨询

基本信息

分子式C30H48O3
分子量456.7
MDL编码MFCD00009619
C46287Alfa AesarBetulinic Acid1611元/250mg;   5228元/1g;   咨询

基本信息

Ref#
46287

分子式
C30H48O3

B8936Sigma-AldrichBetulinic Acid≥98% (HPLC)681.38元/5 MG;   1872.03元/25 MG;   咨询

产品说明

一般描述

Betulinic acid (BetA) is a natural product mostly sourced from the birch tree (Betula spp.). This pentacyclic lupanetype triterpenoid is also associated with other species such as Syzygium spp., Diospyros spp., Ziziphus spp., and Paeonia spp..

应用

Betulinic acid (BetA) has been used:

  • to test its effects as an antiviral agent against Dengue virus (DENV)
  • as a sterol regulatory element-binding protein (SREBP) inhibitor to repress the lipid metabolism and proliferation of clear cell renal cell carcinoma (ccRCC) cells
  • as a treatment to test its anti-tumor properties for cell viability and apoptotic cell death assays in multiple myeloma models

包装

5, 25 mg in glass bottle

生化/生理作用

Betulinic acid displays many biological and pharmacological properties such as anticancer, anti-inflammatory, anti-bacterial, anti-human immunodeficiency virus (HIV), and anti-malarial properties.
桦木酸是一种五环三萜类化合物,通过p53 和 CD95 非依赖性机制直接激活细胞凋亡的线粒体途径选择性地诱导肿瘤细胞凋亡。

基本信息

经验(实验)分子式C30H48O3
分子量456.70
EC 号207-448-8
MDL编号MFCD00009619
PubChem化学物质编号329773146
NACRESNA.25

产品性质

质量水平100
测定≥98% (HPLC)
mp295-298 ℃ (dec.) (lit.)
储存温度2-8℃
SMILES stringCC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O
InChI1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1
InChI keyQGJZLNKBHJESQX-FZFNOLFKSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
855057Sigma-AldrichBetulinic Acidtechnical grade, 90%851.75元/100 MG;   2282.23元/500 MG;   咨询

产品说明

一般描述

白桦脂酸是羽扇豆烷型三萜,可用氧化铬 (VI) 从白桦脂经氧化制得。除了抗 HIV-1 和抗肿瘤活性, 还显示出其他生物活性,如抗炎、抗菌、体外抗疟、驱虫和抗氧化活性。

包装

100, 500 mg in glass bottle

生化/生理作用

桦木酸是一种五环三萜类化合物,通过p53 和 CD95 非依赖性机制直接激活细胞凋亡的线粒体途径选择性地诱导肿瘤细胞凋亡。

基本信息

经验(实验)分子式C30H48O3
分子量456.70
EC 号207-448-8
MDL编号MFCD00009619
PubChem化学物质编号24888370
NACRESNA.22

产品性质

等级technical grade
质量水平100
测定90%
旋光性[α]20/D +7.8°, c = 0.9 in pyridine
mp295-298 ℃ (dec.) (lit.)
储存温度2-8℃
SMILES stringCC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O
InChI1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1
InChI keyQGJZLNKBHJESQX-FZFNOLFKSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
PHL89529Betulinic Acidphyproof® Reference Substance3048.57元/50 MG;   咨询

产品说明

一般描述

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

生化/生理作用

桦木酸是一种五环三萜类化合物,通过p53 和 CD95 非依赖性机制直接激活细胞凋亡的线粒体途径选择性地诱导肿瘤细胞凋亡。

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

基本信息

经验(实验)分子式C30H48O3
分子量456.70
MDL编号MFCD00009619

产品性质

等级primary reference standard
产品线phyproof® Reference Substance
测定≥90.0% (HPLC)
形式powder
manufacturer/tradenamePhytoLab
mp295-298 ℃ (dec.) (lit.)
SMILES stringCC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O
InChI1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1
InChI keyQGJZLNKBHJESQX-FZFNOLFKSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
91466SupelcoBetulinic Acidanalytical standard1759.06元/10 MG;   咨询

产品说明

一般描述

Betulinic acid is a pentacyclic triterpene, isolated from the leaves of Syzigium claviflorum. It is found to be an inhibitor of HIV replication in H9 lymphocyte cells.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Betulinic acid may be used as a reference standard in the determination of betulinic acid in white birch bark using reversed-phase high-performance liquid chromatography (RP-HPLC).

生化/生理作用

桦木酸是一种五环三萜类化合物,通过p53 和 CD95 非依赖性机制直接激活细胞凋亡的线粒体途径选择性地诱导肿瘤细胞凋亡。

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

基本信息

经验(实验)分子式C30H48O3
分子量456.70
EC 号207-448-8
MDL编号MFCD00009619
PubChem化学物质编号329770040

产品性质

质量水平100
等级analytical standard
测定≥97.0% (HPLC)
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp295-298 ℃ (dec.) (lit.)
application(s)food and beverages
格式neat
储存温度2-8℃
SMILES stringCC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O
InChI1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1
InChI keyQGJZLNKBHJESQX-FZFNOLFKSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
M01408FluorochemBetulinic Acid>98%814元/250mg;   1650元/1g;   6754元/5g;   咨询

基本信息

CAS Number472-15-1
MDL NumberMFCD00009619
Melting Point294℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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