CAS 469-59-0; spiro(9h-benzo(a)fluorene-9,2'(3'h)-furo(3,2-b)-pyridin)-11(1h)-one, 2,3,3'a,4,

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货号

品牌

产品名称

规格

包装、参考价格

J860666

MACKLIN

蒜黎芦碱

99%

53元/5mg; 159元/25mg; 430元/100mg; 731元/250mg;

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储存：-20°C
状态：白色到灰白色固体

J792504

MACKLIN

蒜黎芦碱

10mM in DMSO

349元/1ml;

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储存：-20°C

394256

J&K

Jervine

98%, 来源于藜芦

2327元/10MG;

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基本信息

分子式	C₂₇H₃₉NO₃
分子量	425.61
熔点	244-248
MDL编码	MFCD01684066
Beilstein	59109
Merck	14,5264
存储条件	Store at 2-8℃

安全信息

图形或危害标志
提示语	Danger
危险说明	H301
防范说明	P301+P310
UN号码	2811
危险分类	6.1
包装等级	III
WGK	3
RTECS	WG9700000

905225

J&K

Jervine

97%

323元/1MG; 1288元/5MG;

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基本信息

分子式	C₂₇H₃₉NO₃
分子量	425.61
熔点	244-248
MDL编码	MFCD01684066
Beilstein	59109
Merck	5264
存储条件	Store at 2-8℃

安全信息

图形或危害标志
提示语	Danger
危险说明	H301
防范说明	P301+P310
UN号码	2811
危险分类	6.1
包装等级	III
WGK	3
RTECS	WG9700000

950582

J&K

Jervine

98%

4242元/20MG;

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基本信息

分子式	C₂₇H₃₉NO₃
分子量	425.6100
MDL编码	MFCD01684066

J4145

Sigma-Aldrich

Jervine

≥98% (HPLC), powder

1838.92元/1 MG;

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产品说明

一般描述

Jervine is a steroid alkaloid present in Veratrum californicum.

包装

1 mg in glass bottle

生化/生理作用

Jervine is a potent teratogenic agent. It can induce apoptosis in leukemia cells and MUTZ-1 cells. Jervine is an inhibitor of Hedgehog signaling. It exhibits anti-cancer effects on human prostate cancer. It also increases the chemosensitivity of breast cancer cells to doxorubicin treatment. Jervine may be used for treating hypertension and heart disease.
Jervine is a sonic hedgehog (Shh) pathway inhibitor.

基本信息

经验(实验)分子式	C₂₇H₃₉NO₃
分子量	425.60
EC 号	207-417-9
MDL编号	MFCD01684066
PubChem化学物质编号	24896194
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
溶解性	methanol: >2 mg/mL H₂O: insoluble
储存温度	−20℃
SMILES string	[H][C@@]12C[C@H](C)CN[C@@]1([H])[C@@H](C)[C@@]3(CC[C@]4([H])C(=C3C)C(=O)[C@@]5([H])[C@@]4([H])CC=C6C[C@@H](O)CC[C@]56C)O2
InChI	1S/C27H39NO3/c1-14-11-21-24(28-13-14)16(3)27(31-21)10-8-19-20-6-5-17-12-18(29)7-9-26(17,4)23(20)25(30)22(19)15(27)2/h5,14,16,18-21,23-24,28-29H,6-13H2,1-4H3/t14-,16+,18-,19-,20-,21+,23+,24-,26-,27-/m0/s1
InChI key	CLEXYFLHGFJONT-DNMILWOZSA-N
Gene Information	human ... EBP(10682)

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H360D
预防措施声明	P201 - P301 + P310 + P330
危险分类	Acute Tox. 3 Oral - Repr. 1B
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Faceshields, Gloves

M02030

Fluorochem

Jervine

>98%

3432元/10mg;

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基本信息

CAS Number	469-59-0
MDL Number	MFCD01684066
Melting Point	246℃

安全信息

图形或危害标志
危险性说明	H301: Toxic if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation. H360Fd: May damage fertility; Suspected of damaging the unborn child
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: . P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see . on this label). P330: Rinse mouth. P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to local regulations.