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CAS: 453-71-4
分子式: C7H4FNO4
分子量: 185.11
沸点: 92°C 15mm
熔点: 120-128℃
中文名称: 
4-氟-3-硝基苯甲酸
3-硝基-4-氟苯甲酸
英文名称: 
4-fluoro-3-nitrobenzoic acid
性质描述: 类黄色粉末。
用途: 医药中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格
F810014MACKLIN4-氟-3-硝基苯甲酸98%25元/5g;   58元/25g;   咨询
储存:2~8°C
状态:白色到黄色到棕褐色粉末,晶体或块状
F0399TCI4-Fluoro-3-nitrobenzoic Acid>98.0%(GC)(T)225元/5G;   925元/25G;   咨询

基本信息

纯度/分析方法>98.0%(GC)(T)
分子式/分子量C7H4FNO4 = 185.11
外观与形状(20℃)固体
Reaxys-RN2107562
PubChem物质ID87570167
SDBS (AIST Spectral DB)41049
MDL编号MFCD00007058

技术规格

Purity(GC)min. 98.0 %
Purity(Neutralization titration)min. 98.0 %
Melting point120.0 to 124.0 ℃

物性(参考值)

熔点121 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
463132J&K4-Fluoro-3-nitrobenzoic Acid98%168元/5G;   536元/25G;   1914元/100G;   咨询

基本信息

分子式C7H4FNO4
分子量185.11
熔点123-126
MDL编码MFCD00007058
Beilstein2107562
EINECS 编号207-221-3

应用

4-Fluoro-3-nitrobenzoic acid was used: as starting reagent in the preparation of novel benzimidazoles having antimycobacterial activity.in preparation of series of novel acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors containing benzimidazole core structure.in preparation of bis(heterocyclic) skeletal precursors for the Pictet-Spengler reaction.in solid-phase synthesis of trisubstituted [1,3,5]triazino[1,2-a]benzimidazole-2,4(3H,10H)-diones.

安全信息

图形或危害标志
提示语Warning
危险说明H302
H315
H319
H335
H401
防范说明P261
P305+P351+P338
WGK2
TSCA
A10800Alfa Aesar4-Fluoro-3-nitrobenzoic Acid98%469元/5g;   1825元/25g;   6396元/100g;   咨询

基本信息

MDL
MFCD00007058

EINECS
207-221-3

分子式
C7H4FNO4

分子量
185.11

熔点
121-126°

沸点
92°/15mm

形态
Powder

Beilstein
2107562

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

TSCA

C30506Alfa Aesar4-Fluoro-3-nitrobenzoic Acid98%836元/5g;   3301元/25g;   咨询

基本信息

Ref#
30506

MDL
7058

分子式
C7 H4 F N O4

分子量
185.11

329045Sigma-Aldrich4-Fluoro-3-nitrobenzoic Acid98%237.36元/5 G;   769.86元/25 G;   咨询

产品说明

应用

4-Fluoro-3-nitrobenzoic acid was used:

  • as starting reagent in the preparation of novel benzimidazoles having antimycobacterial activity
  • in preparation of series of novel acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors containing benzimidazole core structure
  • in preparation of bis(heterocyclic) skeletal precursors for the Pictet-Spengler reaction
  • in solid-phase synthesis of trisubstituted [1,3,5]triazino[1,2-a]benzimidazole-2,4(3H,10H)-diones

包装

5, 25 g in poly bottle

基本信息

线性分子式FC6H3(NO2)CO2H
分子量185.11
EC 号207-221-3
MDL编号MFCD00007058
PubChem化学物质编号24859766

产品性质

质量水平100
测定98%
mp123-126 ℃ (lit.)
溶解性95% ethanol: soluble 50 mg/mL, clear, light yellow
SMILES stringOC(=O)c1ccc(F)c(c1)[N+]([O-])=O
InChI1S/C7H4FNO4/c8-5-2-1-4(7(10)11)3-6(5)9(12)13/h1-3H,(H,10,11)
InChI keyBOJWTAQWPVBIPG-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
018022Fluorochem4-Fluoro-3-nitrobenzoic Acid98%220元/1g;   264元/10g;   308元/25g;   990元/100g;   咨询

基本信息

CAS Number453-71-4
MDL NumberMFCD00007058
Melting Point123-126℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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