| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 |
| G810424 | MACKLIN | 金雀异黄酮 | 分析标准品,≥98% | 81元/20mg; 1450元/1g; | 展开 |
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| G0272 | TCI | Genistein | >98.0%(HPLC) | 130元/100MG; 370元/1G; | 展开 |
基本信息 | 纯度/分析方法 | >98.0%(HPLC) | | 分子式/分子量 | C15H10O5 = 270.24 | | 外观与形状(20℃) | 固体 | | 储存温度 | 0-10℃ | | 应避免的情况 | 加热 | | 包装和容器 | 100MG-带有塑料内管的玻璃瓶 (查看图片) | | Reaxys-RN | 263823 | | PubChem物质ID | 87570445 | | Merck Index (14) | 4391 | | MDL编号 | MFCD00016952 |
技术规格 | Appearance | White to Light yellow to Light orange powder to crystal | | Purity(HPLC) | min. 98.0 area% |
物性(参考值) 相关法规 |
| 977967 | J&K | Genistein | 98% | 84元/100MG; 173元/500MG; 314元/1G; | 展开 |
基本信息 | 分子式 | C15H10O5 | | 分子量 | 270.24 | | 熔点 | >280 | | MDL编码 | MFCD00016952 | | Beilstein | 263823 | | Merck | 14,4391 | | EINECS 编号 | 207-174-9 | | 存储条件 | Freezer -20℃ |
安全信息 | 图形或危害标志 |  | | 提示语 | Warning | | 危险说明 | H302 | | 防范说明 | P262 | | WGK | 3 | | RTECS | NR2392000 | | TSCA | 是 |
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| 253493 | J&K | Genistein | 99% | 86元/10MG; 88元/25MG; 96元/100MG; | 展开 |
基本信息 | 分子式 | C15H10O5 | | 分子量 | 270.24 | | 熔点 | >280 | | MDL编码 | MFCD00016952 | | Beilstein | 263823 | | Merck | 14,4391 | | EINECS 编号 | 207-174-9 | | 存储条件 | Freezer -20℃ |
安全信息 | 图形或危害标志 | | | 提示语 | Warning | | 危险说明 | H302 | | 防范说明 | P262 | | WGK | 3 | | RTECS | NR2392000 | | TSCA | 是 |
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| 996327 | J&K | Genistein | 来源于大豆, 有效含量≥90%, 可溯源至中检院标准品 | 228元/20MG; | 展开 |
基本信息 | 分子式 | C15H10O5 | | 分子量 | 270.24 | | MDL编码 | MFCD00016952 |
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| G6649 | Sigma-Aldrich | Genistein | synthetic, ≥98% (HPLC), powder | 566.73元/5 MG; 1698.93元/25 MG; 4105.74元/100 MG; | 展开 |
产品说明 一般描述 金雀异黄素是豆科植物家族中存在的一种异黄酮。它在结构上类似于雌激素(雌二醇-17β)。 应用 金雀异黄素已用于：
- 用作评估雌激素活性的试验化合物
- 用作雌激素配体，以进行一致的报告基因活化试验，还用于检验染料木黄素与hER的结合β
- 用作内吞抑制剂，检验内吞晚期，溶酶体上的牛血清白蛋白(AGE-BSA)糖基化末端可能的作用
包装 5 mg in glass bottle
25, 100 mg in poly bottle 生化/生理作用 金雀异黄素对于植物-微生物的相互作用至关重要。它充当天然的化学保护剂，有助于预防肿瘤进展和心脏疾病。金雀异黄素的功能作用与雌激素相同。可用于评估保健和功能食品。金雀异黄素具有抗菌作用，可用作植物抗毒素和植物抗肽原。
酪氨酸蛋白激酶抑制剂; 在其他蛋白激酶反应中，ATP的竞争性抑制剂。 抗血管生成剂，可下调参与控制血管生成的基因的转录。 特点和优势 该化合物在受体分类和信号转导手册中 氯离子通道 和 Met 页面中进行了详细介绍。想要浏览手册的其他页面， 请单击此处。
该化合物是激酶磷酸酶生物学研究的推荐产品。点击此处，了解更多精选激酶磷酸酶生物学产品。了解更多有关用于其他研究领域的生物活性小分子的信息，请访问 sigma.com/discover-bsm。 其他说明 Scripps Center for Metabolomics(斯克里普斯代谢组学中心)独立生成的串联质谱数据，可以PDF格式查看或下载。 G6649.pdf 经过测试的代谢物在Scripps Center for Metabolomics(斯克里普斯代谢组学中心) METLIN代谢物数据库有重点介绍。 更多信息请见sigma.com/metlin。 基本信息 | 经验(实验)分子式 | C15H10O5 | | 分子量 | 270.24 | | Beilstein | 263823 | | EC 号 | 207-174-9 | | MDL编号 | MFCD00016952 | | PubChem化学物质编号 | 24278036 | | NACRES | NA.77 |
产品性质 | 质量水平 | 200 | | 生物来源 | synthetic | | 测定 | ≥98% (HPLC) | | 形式 | powder | | 颜色 | off-white to yellow | | mp | 297.0-298.0 ℃ | | 溶解性 | DMSO: soluble
ethanol: soluble | | 储存温度 | −20℃ | | SMILES string | Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O | | InChI | 1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H | | InChI key | TZBJGXHYKVUXJN-UHFFFAOYSA-N | | Gene Information | human ... AKT1(207), CYP19A1(1588), EGFR(1956), ESR1(2099), ESR2(2100)
mouse ... Esr1(13982), Hexa(15211)
rat ... Adora1(29290), Adora2a(25369), Ar(24208) |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 | | 预防措施声明 | P264 - P270 - P301 + P312 - P501 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | Eyeshields, Faceshields, Gloves, type N95 (US) |
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| G6776 | Sigma-Aldrich | Genistein | from Glycine max (soybean), ~98% (HPLC) | 854.69元/5 MG; 1843.44元/10 MG; | 展开 |
产品说明 一般描述 金雀异黄素是来自大豆的异黄酮营养保健品，同时也是一种植物雌激素。它来源于染料木苷。 应用 金雀异黄素已被用作：
- 作为抗癌剂用于测试其在宫颈腺癌细胞中的细胞毒性
- 作为多酚用于测试其对精子线粒体中活性氧的作用
- 测试其对紫外照射下皮肤和瘢痕疙瘩成纤维细胞的自由基清除作用
包装 5, 10 mg in glass bottle 生化/生理作用 金雀异黄素具有抗氧化功能，并可有效淬灭活性氧。它有益于人体健康。
酪氨酸蛋白激酶抑制剂; 在其他蛋白激酶反应中，ATP的竞争性抑制剂。 抗血管生成剂，可下调参与控制血管生成的基因的转录。 特点和优势 该化合物出现在《受体分类和信号转导手册》的 Met 页面。要浏览其他手册页， 单击此处 。 基本信息 | 经验(实验)分子式 | C15H10O5 | | 分子量 | 270.24 | | Beilstein | 263823 | | EC 号 | 207-174-9 | | MDL编号 | MFCD00016952 | | PubChem化学物质编号 | 24895273 | | NACRES | NA.77 |
产品性质 | 质量水平 | 200 | | 生物来源 | Glycine max (soybean) | | 测定 | ~98% (HPLC) | | 形式 | powder | | mp | > 280 ℃ | | 溶解性 | DMSO: soluble
ethanol: soluble | | 储存温度 | −20℃ | | SMILES string | Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O | | InChI | 1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H | | InChI key | TZBJGXHYKVUXJN-UHFFFAOYSA-N | | Gene Information | human ... AKT1(207), CYP19A1(1588), EGFR(1956), ESR1(2099), ESR2(2100)
mouse ... Esr1(13982), Hexa(15211)
rat ... Adora1(29290), Adora2a(25369), Ar(24208) |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 | | 预防措施声明 | P264 - P270 - P301 + P312 - P501 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | Eyeshields, Faceshields, Gloves, type N95 (US) |
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| 05360590 | | Genistein | primary reference standard | 6165.29元/50MG; | 展开 |
产品说明 一般描述 Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate. 应用 草药产品分析的标准品。 生化/生理作用 酪氨酸蛋白激酶抑制剂; 在其他蛋白激酶反应中，ATP的竞争性抑制剂。 抗血管生成剂，可下调参与控制血管生成的基因的转录。 基本信息 | 经验(实验)分子式 | C15H10O5 | | 分子量 | 270.24 | | Beilstein | 263823 | | EC 号 | 207-174-9 | | MDL编号 | MFCD00016952 | | PubChem化学物质编号 | 329747700 | | NACRES | NA.24 |
产品性质 | 等级 | primary reference standard | | 保质期 | limited shelf life, expiry date on the label | | manufacturer/tradename | HWI | | 储存条件 | under inert gas | | application(s) | food and beverages | | 储存温度 | −20℃ | | SMILES string | Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O | | InChI | 1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H | | InChI key | TZBJGXHYKVUXJN-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 | | 预防措施声明 | P264 - P270 - P301 + P312 - P501 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 345834 | Sigma-Aldrich | Genistein, Soybean-CAS 446-72-0-Calbiochem | A cell-permeable, reversible, substrate competitive inhibitor of protein tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC₅₀ = 2.6 µM). | 1763.65元/20 MG; 3543.57元/50 MG; | 展开 |
产品说明 一般描述 A cell-permeable, reversible, substrate competitive inhibitor of protein tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 = 2.6 µM). The inhibition is competitive with respect to ATP and non-competitive with respect to the phosphate acceptor. Has only a trivial effect on the activity of PKA and PKC (IC50 >350 µM). Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell cycle arrest and apoptosis in Jurkat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Also inhibits topoisomerase II activity in vitro.
A cell-permeable, reversible, substrate competitive inhibitor of protein tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 = 2.6 µM). The inhibition is competitive with respect to ATP and non-competitive with respect to the phosphate acceptor. Inhibits tumor cell proliferation and induces tumor cell differentiation. Inhibits exogenous substrate phosphorylation by EGFR kinase and pp60v-src with similar potencies (IC50 = 20-25 µM). Has only a trivial effect on PKC and PKA (IC50 >350 µM). Produces cell cycle arrest and apoptosis in Jurkat T-leukemia cells. Prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Also inhibits topoisomerase II activity in vitro. Blocks oxidative DNA damage in vitro. 包装 50 mg in Plastic ampoule
20 mg in Glass bottle 生化/生理作用 Cell permeable: yes
Primary Target
EGFR kinase
Target IC50: 2.6 µM against autophosphorylation of epidermal growth factor receptor kinase
Product does not compete with ATP.
Reversible: yes 警告 Toxicity: Standard Handling (A) 其他说明 Constantinou, A., and Huberman, E. 1995. Proc. Soc. Exp. Biol. Med. 208, 109.
Wei, H., et al. 1995. Proc. Soc. Exp. Biol. Med. 208, 124.
Wei, H., et al. 1995. Carcinogenesis17, 73.
Kobayashi, S., et al. 1994. J. Biol. Chem.269, 9011.
Migita, K., et al. 1994. J. Immunol.153, 3457.
Spinozzi, F., et al. 1994. Leuk. Res.18, 431.
Dhar, A., et al. 1990. Mol. Pharmacol.37, 519.
Hill, T.D., et al. 1990. Science248, 1660.
Dean, N.M., et al. 1989. Biochem. Biophys. Res. Commun.165, 795.
Akiyama, T., et al. 1987. J. Biol. Chem.262, 5592. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息 | 经验(实验)分子式 | C15H10O5 | | 分子量 | 270.24 | | MDL编号 | MFCD00016952 |
产品性质 | 质量水平 | 100 | | 测定 | ≥95% (HPLC) | | 形式 | solid | | manufacturer/tradename | Calbiochem® | | 储存条件 | OK to freeze
protect from light | | 颜色 | white | | 溶解性 | DMSO: 200 mg/mL | | 运输 | ambient | | 储存温度 | −20℃ | | InChI | 1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H | | InChI key | TZBJGXHYKVUXJN-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 | | 预防措施声明 | P264 - P270 - P301 + P312 - P501 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 92136 | Supelco | Genistein | analytical standard | 3134.91元/10 MG; | 展开 |
产品说明 一般描述 Genistein是一种天然存在的大豆异黄酮，是一种饮食蛋白酪氨酸激酶(PTK抑制剂。目前发现它具有抗癌特性。 应用 有关合适仪器技术的更多信息，请参考产品分析证书。如需进一步支持，请联系技术服务。 包装 10 mg in glass bottle
无底玻璃瓶。内含物在插入的融合锥体内。 生化/生理作用 酪氨酸蛋白激酶抑制剂; 在其他蛋白激酶反应中，ATP的竞争性抑制剂。 抗血管生成剂，可下调参与控制血管生成的基因的转录。 基本信息 | 经验(实验)分子式 | C15H10O5 | | 分子量 | 270.24 | | Beilstein | 263823 | | EC 号 | 207-174-9 | | MDL编号 | MFCD00016952 | | PubChem化学物质编号 | 329769870 | | NACRES | NA.24 |
产品性质 | 等级 | analytical standard | | 质量水平 | 100 | | 测定 | ≥97% (HPLC) | | 保质期 | limited shelf life, expiry date on the label | | technique(s) | HPLC: suitable
gas chromatography (GC): suitable | | application(s) | food and beverages | | 格式 | neat | | 储存温度 | 2-8℃ | | SMILES string | Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O | | InChI | 1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H | | InChI key | TZBJGXHYKVUXJN-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 | | 预防措施声明 | P264 - P270 - P301 + P312 - P501 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| PHL89199 | | Genistein | phyproof® Reference Substance | 4856.89元/50 MG; | 展开 |
产品说明 一般描述 This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG 生化/生理作用 酪氨酸蛋白激酶抑制剂; 在其他蛋白激酶反应中，ATP的竞争性抑制剂。 抗血管生成剂，可下调参与控制血管生成的基因的转录。 法律信息 phyproof is a registered trademark of PhytoLab GmbH & Co. KG 基本信息 | 经验(实验)分子式 | C15H10O5 | | 分子量 | 270.24 | | Beilstein | 263823 | | MDL编号 | MFCD00016952 |
产品性质 | 等级 | primary reference standard | | 产品线 | phyproof® Reference Substance | | 测定 | ≥95.0% (HPLC) | | 形式 | powder | | manufacturer/tradename | PhytoLab | | 储存温度 | 2-8℃ | | SMILES string | Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O | | InChI | 1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H | | InChI key | TZBJGXHYKVUXJN-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 | | 预防措施声明 | P264 - P270 - P301 + P312 - P501 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| PHR1859 | Supelco | Genistein | Pharmaceutical Secondary Standard; Certified Reference Material | 2391.32元/100 MG; | 展开 |
产品说明 一般描述 Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards 生化/生理作用 酪氨酸蛋白激酶抑制剂; 在其他蛋白激酶反应中，ATP的竞争性抑制剂。 抗血管生成剂，可下调参与控制血管生成的基因的转录。 分析说明 These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. 其他说明 This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. 附注 To see an example of a Certificate of Analysis for this material enter LRAB0086 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. 基本信息 | 经验(实验)分子式 | C15H10O5 | | 分子量 | 270.24 | | Beilstein | 263823 | | EC 号 | 207-174-9 | | MDL编号 | MFCD00016952 | | NACRES | NA.24 |
产品性质 | 质量水平 | 300 | | 等级 | certified reference material
pharmaceutical secondary standard | | CofA | current certificate can be downloaded | | 包装 | pkg of 100 mL | | application(s) | pharmaceutical | | 格式 | neat | | 药典可追溯性 | traceable to USP 1288816 | | 储存温度 | -10 to -25℃ | | SMILES string | Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O | | InChI | 1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H | | InChI key | TZBJGXHYKVUXJN-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 | | 预防措施声明 | P264 - P270 - P301 + P312 - P501 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 1288816 | USP | Genistein | United States Pharmacopeia (USP) Reference Standard | 2914.43元/15 MG; | 展开 |
产品说明 一般描述 This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia. 生化/生理作用 酪氨酸蛋白激酶抑制剂; 在其他蛋白激酶反应中，ATP的竞争性抑制剂。 抗血管生成剂，可下调参与控制血管生成的基因的转录。 分析说明 These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. 其他说明 USP issued SDS can be found here.
Sales restrictions may apply. 基本信息 | 经验(实验)分子式 | C15H10O5 | | 分子量 | 270.24 | | Beilstein | 263823 | | MDL编号 | MFCD00016952 | | PubChem化学物质编号 | 329749932 | | NACRES | NA.24 |
产品性质 | 等级 | pharmaceutical primary standard | | manufacturer/tradename | USP | | application(s) | pharmaceutical (small molecule) | | 格式 | neat | | 储存温度 | −20℃ | | SMILES string | Oc1ccc(cc1)C2=COc3cc(O)cc(O)c3C2=O | | InChI | 1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H | | InChI key | TZBJGXHYKVUXJN-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 | | 预防措施声明 | P264 - P270 - P301 + P312 - P501 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| M01798 | Fluorochem | Genistein | >98% | 220元/1g; 374元/5g; 1254元/25g; 4268元/100g; | 展开 |
基本信息 | CAS Number | 446-72-0 | | MDL Number | MFCD00016952 | | Melting Point | 297-298℃ |
安全信息 | 图形或危害标志 | | | 危险性说明 | H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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