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CAS: 434-16-2
分子式: C27H44O
分子量: 384.65
熔点: 147-151℃
中文名称: 
维生素D3前体
胆甾-5,7-二烯-3β-醇
(3β)-7-去氢胆甾醇
3β-羟基胆甾-5,7-二烯
3β-胆甾-5,7-二烯-3-醇
7-脱氢胆甾醇一水合物
英文名称: 
3-Hydroxycholesta-5,7-diene
Cholesta-5,7-dien-3-ol
(3)-7-Dehydrochlesterol
Provitamin D3
7-dien-3-ol, (3.beta.)-Cholesta-5
5,7-Cholestandien-3.beta.-ol
cholesta-5,7-dien-3-beta-ol
5,7-cholestadien-3-beta-ol
7,8-didehydrocholesterol
7-dehydrocholesterin
7-dehydrocholesterol
(3 beta)-cholesta-7-dien-3-ol
(3-beta)-cholesta-7-dien-3-ol
7-dehydro-cholestero
dehydrocholesterin
dehydrocholesterol
delta(sup 5,7)-cholesterol
delta(sup 7)-cholesterol
provitamin d(sub 3)
Cholesta-5,7-dien-3-ol,(3.beta.)-
展开更多英文名
性质描述: 片状结晶（甲醇水溶液/乙醚）。熔点150-151℃（无水物）。[α]20/D-113.6°（氯仿）。露置空气中易氧化。
生产方法: 猪皮中分离提取，亦可用胆甾醇经酯化、溴化、消除、水解制得。
用途: 维生素D3的中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
D873605MACKLIN脱氢胆固醇优级试剂, 95%178元/5mg;   298元/25mg;   495元/100mg;   1159元/500mg;   展开
储存：-20℃
状态：白色到微黄色粉末或晶体
D875289MACKLIN脱氢胆固醇95%65元/1g;   198元/5g;   710元/25g;   2481元/100g;   9000元/500g;   展开
储存：-20℃
状态：白色到微黄色粉末或晶体
30800Sigma-Aldrich7-Dehydrocholesterol≥95.0% (HPLC)802.79元/5 G;   展开

产品说明

一般描述

7-脱氢胆固醇(7-DHC)为5,7-共轭二烯固醇，是胆固醇的生物合成前体。暴露于紫外线B(UVB)辐射下时，它有助于产生维生素D3 。

应用

7-脱氢胆固醇已用作测定固醇的内标品。

生化/生理作用

下调培养的 Smith-Lemi-Opitz 综合征皮肤成纤维细胞的胆固醇生物合成。

其他说明

斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDF30800.pdf 中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息，请访问sigma.com/metlin。

基本信息

经验(实验)分子式C27H44O
分子量384.64
Beilstein2224615
EC 号207-100-5
MDL编号MFCD00003624
eCl@ss39023139
PubChem化学物质编号57648485
NACRESNA.79

产品性质

质量水平100
生物来源synthetic
测定≥95.0% (HPLC)
形式powder or crystals
旋光性[α]20/D -115±8°, c = 1% in chloroform
颜色 white to faint yellow
mp148-152 ℃ (lit.)
储存温度−20℃
SMILES string[H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C
InChI1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3/t19-,21+,23-,24+,25+,26+,27-/m1/s1
InChI keyUCTLRSWJYQTBFZ-DDPQNLDTSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
700066PAvanti7-DehydrocholesterolΔ,5,7-cholesterol, powder1861.99元/5 MG;   展开

产品说明

一般描述

7-dehydrocholesterol is a metabolite produced in cholesterol synthesis. It is an unsaturated sterol predominantly found in the epidermis.

应用

7-dehydrocholesterol has been used:

  • in gas chromatography/mass spectrometry (GC/MS)-based sterol profiling to quantify 7-dehydrocholesterol in oligodendrocyte progenitor cells (OPCs)
  • as an internal standard for the analysis of sterols and oxysterols using ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
  • as an internal standard for lipid measurements by liquid chromatography (LC)-MS

生化/生理作用

7-dehydrocholesterol acts as a precursor of vitamin D3 under the conditions of high temperature and ultraviolet (UV) light.

包装

5 mL Amber Glass Screw Cap Vial (700066P-5mg)

基本信息

经验(实验)分子式C27H44O
分子量384.64
NACRESNA.25

产品性质

测定>99% (TLC)
形式powder
包装pkg of 1 × 5 mg (700066P-5mg)
manufacturer/tradenameAvanti Polar Lipids 700066P
运输dry ice
储存温度−70℃
InChI1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3
InChI keyUCTLRSWJYQTBFZ-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHR2439SupelcoCholecalciferol Impurity BPharmaceutical Secondary Standard; Certified Reference Material4606.11元/100 MG;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

生化/生理作用

下调培养的 Smith-Lemi-Opitz 综合征皮肤成纤维细胞的胆固醇生物合成。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC5946 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C27H44O
分子量384.64
Beilstein2224615
MDL编号MFCD00003624

产品性质

等级certified reference material
pharmaceutical secondary standard
形式powder
包装pkg of 100 mg
mp148-152 ℃ (lit.)
储存温度-10 to -25℃
SMILES string[H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C
InChI1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9-10,18-19,21,23-25,28H,6-8,11-17H2,1-5H3/t19-,21+,23-,24+,25+,26+,27-/m1/s1
InChI keyUCTLRSWJYQTBFZ-DDPQNLDTSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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