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CAS: 434-13-9
分子式: C24H40O3
分子量: 376.57
熔点: 182-186℃
中文名称: 
石胆酸
英文名称: 
3-alpha-hydroxy-5-beta-cholan-24-oic aci
17-beta-(1-methyl-3-carboxypropyl)ethiocholan-3-alpha-ol
17beta-(1-methyl-3-carboxypropyl)etiocholan-3alpha-ol
3-alpha-hydroxy-5-beta-cholanic acid
3-alpha-hydroxycholanic acid
3-hydroxycholan-24-oic acid
3alpha-hydroxy-5beta-cholan-24-oic acid
3alpha-hydroxy-5beta-cholanic acid
3alpha-hydroxy-5beta-cholanoic acid
3alpha-hydroxycholanic acid
3-alpha-hydroxy-5-beta-cholanic aci
3alpha-hydroxy-5beta-cholan-24-oic aci
3-hydroxy-, (3 alpha,5 beta)-cholan-24-oic aci
3-hydroxy-, (3-alpha,5-beta)-cholan-24-oic aci
3-hydroxy-, (3alpha,5beta)-cholan-24-oic aci
lithocholic acid
nci-c03861
展开更多英文名
推荐供应商
货号品牌产品名称规格包装、参考价格详情
L812392MACKLIN石胆酸98%52元/1g;   157元/5g;   615元/25g;   2262元/100g;   展开
储存:2~8°C
状态:白色到灰白色粉末
折射率:35.5 ° (C=1, EtOH)
L794428MACKLIN石胆酸10mM in DMSO108元/1ml;   展开
储存:-20°C
状态:液体
L0089TCILithocholic Acid>98.0%(T)560元/5G;   1590元/25G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C24H40O3 = 376.58
外观与形状(20℃)固体
Reaxys-RN3217757
PubChem物质ID87572051
SDBS (AIST Spectral DB)10707
Merck Index (14)5545
MDL编号MFCD00003682

技术规格

AppearanceWhite to Almost white powder to crystaline
Purity(GC)min. 97.0 %
Purity(Neutralization titration)min. 98.0 %
Melting point185.0 to 190.0 ℃
Specific rotation [a]20/D+33.0 to +38.0 deg(C=1, EtOH)

物性(参考值)

熔点186 ℃
比旋光度 [α]D35.5° (C=1,EtOH)
水溶性不溶
在水中的溶解度0.38 mg/l   25 ℃
溶解性(微溶于)乙醇

安全信息

图形或危害标志
信号词警告
危险性说明H303 : 吞咽可能有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P312 : 如感觉不适,呼叫急救中心/医生。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#FZ2275000
980912J&KLithocholic Acid98%465元/5G;   1325元/25G;   展开

基本信息

分子式C24H40O3
分子量376.58
熔点183-188
比旋光度([α]20D)+33.0° to +38.0 °(C=1, EtOH)
MDL编码MFCD00003682
Beilstein3217757
EINECS 编号207-099-1

安全信息

WGK2
RTECSFZ2275000
C22909Alfa AesarLithocholic Acid95%690元/5g;   1873元/25g;   展开

基本信息

Ref#
22909

MDL
3682

分子式
C24 H40 O3

分子量
376.57

L6250Sigma-AldrichLithocholic Acid≥95%854.89元/10 G;   2713.08元/25 G;   展开

产品说明

一般描述

石胆酸是胆汁酸的低聚(乙二醇)衍生物。

应用

石胆酸已用于一项评估胆汁淤积及其对大鼠几个器官和组织的作用的研究。它也被用于一项通过TGF激活SMAD3来研究肝磷脂和胆汁酸稳态的调节的研究。

包装

10, 25 g in poly bottle

生化/生理作用

胆汁酸

其他说明

斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDF L6250.pdf 中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息,请访问sigma.com/metlin。

基本信息

经验(实验)分子式C24H40O3
分子量376.57
Beilstein3217757
EC 号207-099-1
MDL编号MFCD00003682
PubChem化学物质编号24896429
NACRESNA.25

产品性质

生物来源bovine bile
synthetic
质量水平200
测定≥95%
分子量 376.57 g/mol
mp183-188 ℃ (lit.)
官能团carboxylic acid
运输ambient
储存温度room temp
SMILES string[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC(O)=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
InChI1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1
InChI keySMEROWZSTRWXGI-HVATVPOCSA-N
Gene Informationhuman ... POLA1(5422), TOP2A(7153)
rat ... Polb(29240)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
L0720800Lithocholic AcidEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 60 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C24H40O3
分子量376.57
Beilstein3217757
MDL编号MFCD00003682
PubChem化学物质编号329817372
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp183-188 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES string[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC(O)=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
InChI1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1
InChI keySMEROWZSTRWXGI-HVATVPOCSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
BP927Lithocholic AcidBritish Pharmacopoeia (BP) Reference Standard1916.08元/25 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C24H40O3
分子量376.57
Beilstein3217757
MDL编号MFCD00003682

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
mp183-188 ℃ (lit.)
格式neat
储存温度2-8℃
SMILES string[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC(O)=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
InChI1S/C24H40O3/c1-15(4-9-22(26)27)19-7-8-20-18-6-5-16-14-17(25)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21,25H,4-14H2,1-3H3,(H,26,27)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1
InChI keySMEROWZSTRWXGI-HVATVPOCSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
241301FluorochemLithocolic acid98%220元/1g;   616元/5g;   2332元/25g;   7018元/100g;   展开

基本信息

CAS Number434-13-9
MDL NumberMFCD00003682
Melting Point185-190℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H303: May be harmful if swallowed
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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