| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 |
| S879165 | MACKLIN | SKA-31 | ≥99% | 71元/5mg; 101元/10mg; 258元/50mg; 801元/250mg; | 展开 |
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| Y10853 | Alfa Aesar | SKA-31 | | 5103元/25mg; 7810元/50mg; 13372元/100mg; | 展开 |
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| S5576 | Sigma-Aldrich | SKA-31 | ≥98% (HPLC) | 1613.49元/5 MG; 9035.8元/25 MG; | 展开 |
产品说明 包装 5, 25 mg in glass bottle 生化/生理作用 SKA31 is an activator of KCa2 and KCa3.1 Potassium Channels, Potentiates the EDHF Response and Lowers Blood Pressure.
SKA-31 is an activator of KCa2 and KCa3.1 calcium-activated potassium channels. Its EC50 is almost identical at 2-3 μM for all KCa2 subtypes, and about 10-fold lower (260 nM) at KCa3.1 channels. It has significant blood-pressure reducing activity in experimentally hypertensive mice, suggesting potassium channel activation as a therapeutic target for hypertension. 基本信息 | 经验(实验)分子式 | C11H8N2S | | 分子量 | 200.26 | | MDL编号 | MFCD00051329 | | PubChem化学物质编号 | 329824457 |
产品性质 | 质量水平 | 100 | | 测定 | ≥98% (HPLC) | | 形式 | solid | | 溶解性 | DMSO: ≥30 mg/mL | | 储存温度 | −20℃ | | SMILES string | Nc1nc2c(ccc3ccccc23)s1 | | InChI | 1S/C11H8N2S/c12-11-13-10-8-4-2-1-3-7(8)5-6-9(10)14-11/h1-6H,(H2,12,13) | | InChI key | FECQXVPRUCCUIL-UHFFFAOYSA-N |
安全信息 | 象形图 |  | | 警示用语： | Warning | | 危险声明 | H302 - H319 | | 预防措施声明 | P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 | | 储存分类代码 | 11 - Combustible Solids | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 358001 | Fluorochem | Naphtho[1,2-d]thiazol-2-ylamine | 95+% | 2002元/250mg; 3190元/500mg; 5016元/1g; 10032元/2.5g; | 展开 |
基本信息 | CAS Number | 40172-65-4 | | MDL Number | MFCD00051329 |
安全信息 | 图形或危害标志 | | | 危险性说明 | H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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