| CAS: | 39674-97-0 | ||
| 分子式: | C14H11NO3 | ||
| 分子量: | 241.24 | ||
| 英文名称: |
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| 用途: | BVT948 是一种蛋白酪氨酸磷酸酶 (PTP) 的抑制剂，也可以抑制几种细胞色素 P450 (P450) 异构体和赖氨酸甲基转移酶 SETD8 (KMT5A)。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| B879184 | MACKLIN | BVT948 | 99% | 775元/5mg; 1691元/25mg; | 咨询 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
储存：2-8℃ 状态：红色固体 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| B6060 | Sigma-Aldrich | BVT.948 | ≥98% (HPLC), solid | 1896.74元/1 MG; | 咨询 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
产品说明 包装 1 mg in glass bottle 生化/生理作用 BVT.948 is a non-competitive inhibitor of protein tyrosine phosphatase (PTP). Enhances insulin signaling in cells and inhibits several cytochrome P450 isoforms in vitro. 特点和优势 BVT.948 is a non-competitive inhibitor of protein tyrosine phosphatase (PTP). Enhances insulin signaling in cells and inhibits several cytochrome P450 isoforms in vitro. Works through a different mechanism then the other PTP inhibitors. BVT.948 was able to enhance insulin signaling in cells, although it did not increase tyrosine phosphorylation globally. Furthermore, the compound was active in vivo, enhancing insulin tolerance tests in ob/ob mice, therefore apparently enhancing insulin sensitivity. BVT.948 was able to inhibit several other PTPs tested and also was efficient at inhibiting several cytochrome P450 isoforms in vitro. 基本信息
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