基本信息

安全信息

图形或危害标志
提示语	Warning
危险说明	H315 H319 H335 H227
防范说明	P210 P261 P280 P305+P351+P338 P405 P501a

应用
Reagent is an effective product for the synthesis of difluoromethylated phenols in the presence of mild base and aqueous solvent.

备注
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

基本信息

MDL
MFCD00042123

EINECS
000-000-0

分子式
C₈H₅ClF₂O

分子量
190.58

沸点
95-97°/37mm

闪点
72°(161°F)

密度
1.293

折射率
1.4970

灵敏度
Ambient temperatures.

溶解性
Difficult to mix.

Beilstein
2251448

GHS危害和防范说明

GHS符号

Hazard Statements
H227-H315-H319-H335
Combustible liquid.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P210e-P261-P280a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

TSCA
否

产品说明

一般描述

2-Chloro-2,2-difluoroacetophenone is a difluorocarbene reagent, which is generally used in the synthesis of 2,2-difluoro enol silyl ethers, and gem -difluoromethene derived compounds.

应用

2-Chloro-2,2-difluoroacetophenone can be used:

• As a reagent in the difluoromethylation of various phenols to yield aryl difluoromethyl ethers.
• As a precursor in the Baylis-Hillman reaction of fluoroalkyl ketones to obtain chlorodifluoromethyl containing products.
• As a substrate in the synthesis of propargyl alcohols using a novel ruthenium catalyst.

包装

1, 10 g in glass bottle

基本信息

产品性质

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	10 - Combustible liquids
WGK	WGK 3
闪点(F)	160.0 °F
闪点(C)	71.1 ℃

基本信息

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .