| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |
| M795536 | MACKLIN | 1-甲基-4-苯基吡啶碘化物 | 10mM in DMSO | 205元/1ml; | 咨询 |
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| M875357 | MACKLIN | 1-甲基-4-苯基吡啶碘化物 | ≥98% | 280元/25mg; 850元/100mg; 3098元/500mg; 4902元/1g; 14456元/5g; | 咨询 |
储存：室温,干燥,密封,避光 状态：白色到米黄色到浅黄色到黄色粉末 |
| D048 | Sigma-Aldrich | MPP+ iodide | ≥98% (HPLC), powder | 2361.15元/100 MG; 14067.7元/1 G; | 咨询 |
产品说明 一般描述 1-甲基-4-苯基吡啶(MPP+)可通过抑制纹状体突触体中的线粒体氧化还原功能而诱发神经毒性。它是一种潜在的神经毒素并可在动物模型中诱导帕金森症。它可通过在小脑颗粒神经元和神经母细胞瘤细胞中产生活性氧来介导细胞凋亡。MPP+可调控多巴胺的分布。它可通过激活神经元一氧化氮合酶(nNOS)而引起神经毒性，产生过量的一氧化氮。 应用 MPP+碘化物已用于： - 在斑马鱼胚胎中诱导氧化应激
- 抑制星形胶质细胞线粒体中谷氨酸的摄入
- 在小胶质细胞(BV2)中使用MTT(3(4,5-二甲基噻唑)-2-基-2,5-二苯基四唑溴化物)检测细胞活力
包装 1 g in glass bottle
100 mg in glass bottle 生化/生理作用 MPP+碘化物是多巴胺能神经毒素MPTP的一种活性代谢物。 注意 光敏感的。 制备说明 溶液应新鲜制备。 基本信息 | 经验(实验)分子式 | C12H12IN | | 分子量 | 297.13 | | MDL编号 | MFCD00055096 | | PubChem化学物质编号 | 24893235 | | NACRES | NA.77 |
产品性质 | 质量水平 | 100 | | 测定 | ≥98% (HPLC) | | 形式 | powder | | 储存条件 | desiccated | | 颜色 | white to beige | | 溶解性 | H2O: 10 mg/mL, clear | | SMILES string | [I-].C[n+]1ccc(cc1)-c2ccccc2 | | InChI | 1S/C12H12N.HI/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11;/h2-10H,1H3;1H/q+1;/p-1 | | InChI key | RFDFRDXIIKROAI-UHFFFAOYSA-M |
安全信息 | 象形图 |  | | 警示用语： | Danger | | 危险声明 | H301 + H311 + H331 - H315 - H319 - H335 | | 预防措施声明 | P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 | | 靶器官 | Respiratory system | | 储存分类代码 | 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
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| 510846 | Fluorochem | 1-Methyl-4-phenylpyridinium iodide | 95% | 12166元/1g; | 咨询 |
基本信息 | CAS Number | 36913-39-0 | | MDL Number | MFCD00055096 |
安全信息 | 图形或危害标志 | | | 危险性说明 | H301: Toxic if swallowed.
H311: Toxic in contact with skin.
H331: Toxic if inhaled.
| | 防范说明 | P260: Do not breathe .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P311: Call a POISON CENTER or doctor/physician.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P322: Specific measures (see . on this label).
P330: Rinse mouth.
P361: Remove/Take off immediately all contaminated clothing.
P363: Wash contaminated clothing before reuse.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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