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CAS: 367-21-5
分子式: C6H5ClFN
分子量: 145.56
沸点: 230℃
熔点: 42-47℃
中文名称: 
4-氟-3-氯苯胺
3-氯-4-氟苯胺
氟氯苯胺
英文名称: 
3-chloro-4-fluoro-aniline
Fluorochloroaniline
3-Chloro-4-fluorobenzenamine
3-Chloro-4-fluoro aniline
3-chloro-4-fluoro-Benzenamine
3-Chloro-4-fluoroaniline
3-chloro-4-fluoro-benzenamin
Benzenamine,3-chloro-4-fluoro-
性质描述: 白色结晶粉末。熔点44℃(45-47℃),沸点227-228℃,闪点149℃。
生产方法: 以邻二氯苯为原料,经硝酸硝化、氢气还原而得。
用途: 药物合成氟哌酸(诺氟沙星)的重要中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C804797MACKLIN3-氯-4-氟苯胺99%30元/25g;   57元/100g;   217元/500g;   758元/2.5kg;   展开
储存:室温
状态:白色晶体粉末
折射率:1,54-1,542
C1024TCI3-Chloro-4-fluoroaniline>98.0%(GC)165元/25G;   1695元/500G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C6H5ClFN = 145.56
外观与形状(20℃)固体
Reaxys-RN1562786
PubChem物质ID87566061
SDBS (AIST Spectral DB)19945
MDL编号MFCD00007767

技术规格

AppearanceGray to Dark purple to Black powder to crystal
Purity(GC)min. 98.0 %
Purity(Nonaqueous Titration)min. 97.0 %
Melting point45.0 to 47.0 ℃

物性(参考值)

熔点45 ℃

安全信息

图形或危害标志
信号词危险
危险性说明H301 + H311 + H331 : 吞咽、皮肤接触或吸入中毒。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P271 : 只能在室外或通风良好之处使用。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P361 + P364 : 立即脱掉所有沾染的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P310 + P330 : 如误吞咽:立即呼叫急救中心/医生。漱口。
P302 + P352 + P312 : 如皮肤沾染:用水充分清洗。如感觉不适,呼叫急救中心/医生。
P304 + P340 + P311 : 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。呼叫急救中心/医生。
P403 + P233 : 存放在通风良好的地方。保持容器密闭。
P405 : 存放处须加锁。

运输信息

UN编号UN2811
类别6.1
包装类别 III
监管条件代码(*)
219529J&K3-Chloro-4-fluoroaniline98%109元/25G;   358元/100G;   1430元/500G;   展开

基本信息

分子式C6H5ClFN
分子量145.56
熔点45-47
沸点227-228
闪点110
MDL编码MFCD00007767
Beilstein1562786
EINECS 编号206-682-8

安全信息

图形或危害标志
提示语Danger
危险说明H301
H305
H311
H372
防范说明P261
P280
P301+P310
P311
UN号码2811
危险分类6.1
包装等级II
WGK2
TSCA
A11858Alfa Aesar3-Chloro-4-fluoroaniline98%385元/25g;   1568元/100g;   6072元/500g;   展开

基本信息

MDL
MFCD00007767

EINECS
206-682-8

分子式
C6H5ClFN

分子量
145.56

熔点
44-47°

沸点
227-230°

闪点
149°(300°F)

密度
1.420

灵敏度
Ambient temperatures.

形态
Crystalline solid

Beilstein
1562786

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H311-H332-H315-H319-H373
Harmful if swallowed.Toxic in contact with skin.Harmful if inhaled.Causes skin irritation.Causes serious eye irritation.May cause damage to organs through prolonged or repeated exposure.

Precautionary Statements
P260-P280-P305+P351+P338-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray.Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
6.1

包装组
III

危险类别
20/21/22-33-36/38
Harmful by inhalation, in contact with skin and if swallowed.Danger of cumulative effects.Irritating to eyes and skin.

安全等级
26-28-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer).Wear suitable protective clothing and gloves.

欧盟危险品标志

TSCA

228583Sigma-Aldrich3-Chloro-4-fluoroaniline98%327.12元/25 G;   1243.06元/100 G;   展开

产品说明

一般描述

The exposure of workers to 3-chloro-4-fluoroaniline (CFA) was monitored by an HPLC method.

包装

25, 100 g in glass bottle

基本信息

线性分子式ClC6H3(F)NH2
分子量145.56
Beilstein1562786
EC 号206-682-8
MDL编号MFCD00007767
PubChem化学物质编号24853696
NACRESNA.22

产品性质

质量水平100
测定98%
bp227-228 ℃ (lit.)
mp42-44 ℃ (lit.)
SMILES stringNc1ccc(F)c(Cl)c1
InChI1S/C6H5ClFN/c7-5-3-4(9)1-2-6(5)8/h1-3H,9H2
InChI keyYSEMCVGMNUUNRK-UHFFFAOYSA-N

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H301 + H311 + H331 - H373
预防措施声明P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311 - P314
危险分类Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - STOT RE 2
储存分类代码6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 2
闪点(F)230.0 °F - closed cup
闪点(C)110 ℃ - closed cup
个人防护装备Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
8.18752Sigma-Aldrich3-Chloro-4-fluoroanilinefor synthesis384.17元/25 G;   展开

产品说明

分析说明

Assay (GC, area%): ≥ 98.0 % (a/a)
Melting range (lower value): ≥ 42 °C
Melting range (upper value): ≤ 45 °C
Identity (IR): passes test

基本信息

线性分子式3-(Cl),4-(F)C6H3NH2
分子量145.56
MDL编号MFCD00007767
EC索引号206-682-8

产品性质

质量水平200
蒸汽压0.01 hPa ( 20 ℃)
测定≥98.0% (GC)
效能506 mg/kg LD50, oral (Rat)
pH值(酸碱度)7 (20 ℃, 10 g/L in H2O)
bp230 ℃/1013 hPa
mp42-45 ℃
转变温度flash point 114 ℃
密度1.59 g/cm3
堆积密度1000 kg/m3
储存温度2-30℃
InChI1S/C6H5ClFN/c7-5-3-4(9)1-2-6(5)8/h1-3H,9H2
InChI keyYSEMCVGMNUUNRK-UHFFFAOYSA-N

安全信息

象形图GHS06GHS08
警示用语:Danger
危险声明H301 + H311 + H331 - H373
预防措施声明P260 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P314
危险分类Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - STOT RE 2
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 2
闪点(F)230.0 °F - closed cup
闪点(C)110 ℃ - closed cup
001682Fluorochem3-Chloro-4-fluoroaniline98%462元/100g;   1606元/500g;   展开

基本信息

CAS Number367-21-5
MDL NumberMFCD00007767
Boiling Point227-228℃
Melting Point42-47℃

安全信息

图形或危害标志
危险性说明 H301: Toxic if swallowed.
H311: Toxic in contact with skin.
H331: Toxic if inhaled.
防范说明 P260: Do not breathe .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P311: Call a POISON CENTER or doctor/physician.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P322: Specific measures (see . on this label).
P330: Rinse mouth.
P361: Remove/Take off immediately all contaminated clothing.
P363: Wash contaminated clothing before reuse.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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