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CAS: 36330-85-5
分子式: C16H14O3
分子量: 254.290
熔点: 184-187℃
中文名称: 
芬布芬
联苯丁酮酸
苯布芬
英文名称: 
1'-biphenyl)-4-butanoic acid, gamma-oxo-(
3-(4-biphenylylcarbonyl)propionic acid
3-(4-phenylbenzoyl)propionic acid
4-(4-biphenylyl)-4-oxobutyric acid
beta,p-phenylbenzoylpropionic acid
bufemid
butyric acid 4-(4-biphenyl)-4-oxo-
cinopal
diphenyl acetoacetate
cl 82204
diphenyl-4-gamma-oxo-gamma-butyric acid
fenbufen
gamma-oxo(1,1'-biphenyl)-4-butanoic acid
lederfen
napanol
3-(4-biphenylylcarbonyl)-propionic aci
γ-Oxo-(1,1'-biphenyl)-4-butanoic acid
展开更多英文名
性质描述: 白色或类白色针状结晶。熔点185-187℃。溶于冰醋酸、乙醇、氯仿、乙醚,稍溶于酮,几乎不溶于水和石油醚。无臭,味酸。
生产方法: 在无水三氯化铝存在下,联苯和琥珀酸酐在硝基苯中缩合,制得芬布芬,收率为70%。
用途: 该品属丁酸类非甾抗炎药,作用较强,不良反应较小。其作用机理是抑制前列腺素合成,镇痛效果与阿斯匹林相仿。主要用于治疗类风湿性关节炎及风湿性关节炎、骨关节炎、痛风、强直性脊椎炎,也用于牙痛、手术后疼痛、外伤疼痛等。
推荐供应商
货号品牌产品名称规格包装、参考价格
F766680MACKLIN芬布芬10mM in DMSO455元/1ml;   咨询
储存:-20°C
F838501MACKLIN芬布芬97%30元/1g;   38元/5g;   89元/25g;   270元/100g;   1072元/500g;   咨询
储存:室温
状态:白色到灰白色固体
H60557Alfa Aesar4-(4-Biphenylyl)-4-oxobutyric acid96%730元/1g;   3776元/5g;   咨询

基本信息

MDL
MFCD00056701

EINECS
252-979-0

分子式
C16H14O3

分子量
254.28

熔点
184-187°

形态
Powder

GHS危害和防范说明

GHS符号

Hazard Statements
H301
Toxic if swallowed.

Precautionary Statements
P264-P270-P301+P310a-P321-P405-P501a
Wash thoroughly after handling.Do not eat, drink or smoke when using this product.Do not eat, drink or smoke when using this product.Specific treatment (see label).Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

UN#
UN2811

危险等级
6.1

包装组
III

危险类别
25
Toxic if swallowed.

安全等级
20-36-45-60
When using do not eat or drink.Wear suitable protective clothing.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste

RTECS
DV1761000

TSCA

F0041000FenbufenEuropean Pharmacopoeia (EP) Reference Standard1861.35元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

线性分子式C6H5C6H4CO(CH2)2CO2H
分子量254.28
MDL编号MFCD00056701
PubChem化学物质编号329799623
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp184-187 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringOC(=O)CCC(=O)c1ccc(cc1)-c2ccccc2
InChI1S/C16H14O3/c17-15(10-11-16(18)19)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2,(H,18,19)
InChI keyZPAKPRAICRBAOD-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P301 + P310 + P330
危险分类Acute Tox. 3 Oral
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP354FenbufenBritish Pharmacopoeia (BP) Reference Standard2144.18元/100 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

线性分子式C6H5C6H4CO(CH2)2CO2H
分子量254.28
MDL编号MFCD00056701
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
mp184-187 ℃ (lit.)
格式neat
储存温度2-8℃
SMILES stringOC(=O)CCC(=O)c1ccc(cc1)-c2ccccc2
InChI1S/C16H14O3/c17-15(10-11-16(18)19)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h1-9H,10-11H2,(H,18,19)
InChI keyZPAKPRAICRBAOD-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301
预防措施声明P264 - P270 - P301 + P310 + P330 - P405 - P501
危险分类Acute Tox. 3 Oral
储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
207216Fluorochem4-(4-Biphenyl)-4-oxobutyric acid97%418元/1g;   10296元/25g;   咨询

基本信息

CAS Number36330-85-5
MDL NumberMFCD00056701
Melting Point184 - 187 ℃

安全信息

图形或危害标志
危险性说明 H301: Toxic if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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