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CAS: 35773-42-3
分子式: C20H18N2O3
分子量: 334.36852
英文名称: 
3-(2-benzoxazolyl)-7-(diethylamino)-2h-1-benzopyran-2-on
用途: EMI1 (EGFR MaMTH Inhibitor 1) is a novel EGFR ex19del/T790M/C797S inhibitor.
推荐供应商
货号品牌产品名称规格包装、参考价格详情
E910615MACKLINEMI1 (EGFR MaMTH Inhibitor 1)98%2180元/1mg;   7620元/5mg;   11424元/10mg;   展开
储存:-20°C,密闭,干燥
SML2914Sigma-AldrichEMI1≥98% (HPLC)833.87元/5 MG;   4208.37元/25 MG;   展开

产品说明

生化/生理作用

EMI1 (ChemBridge 5213777) is a call penetrant and potent inhibitor of EGFR signaling in EGFR L858R/T790M/C797S and ex19del/T790M/C797S triple mutants associated with drug-resistant NSCLC. Additionally, EMI1 potently depolymerized interphase microtubules, disrupts spindle formation and induced mitotic block in PC9 EGFR ex19del/T790M/C797S cells. EMI1 exhibits potent anti-proliferative activity against various cancer cell lines.

基本信息

经验(实验)分子式C20H18N2O3
分子量334.37
MDL编号MFCD00489515

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度2-8℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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