| CAS: | 328541-79-3 | |
| 分子式: | C19H15Br2N3O3 | |
| 分子量: | 493.15 | |
| 英文名称: |
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| 用途: | GlyH-101是一种选择性且可逆的CFTR抑制剂，其Ki为4.3 μM。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||||||
| G793242 | MACKLIN | GlyH-101 | 10mM in DMSO | 841元/1ml; | 咨询 | ||||||||||||||||||||||||||||||||
储存：-20°C, 干燥, 避光 | |||||||||||||||||||||||||||||||||||||
| G872853 | MACKLIN | GlyH-101 | 99% | 334元/5mg; 1374元/25mg; | 咨询 | ||||||||||||||||||||||||||||||||
储存：-20℃ 状态：黄色固体 | |||||||||||||||||||||||||||||||||||||
| 219671 | Sigma-Aldrich | CFTR Inhibitor II, GlyH-101-CAS 328541-79-3-Calbiochem | CFTR Inhibitor II, GlyH-101, CAS 328541-79-3, is a cell-permeable potent, selective and reversible open-channel blocker of CFTR (Ki = 4.3 µM in CFTR-expressing FRT cells). | 2897.81元/5 MG; | 咨询 | ||||||||||||||||||||||||||||||||
产品说明 一般描述 A cell-permeable glycinyl hydrazone compound that acts as a potent, selective and reversible open-channel blocker of CFTR with intermediate speed (<1 min; 95% inhibition at 50 µM; Ki = 4.3 µM in CFTR-expressing FRT cells for apical membrane Cl- current) and exhibits desirable aqueous solubility. Shown to produce inwardly rectifying CFTR Cl- currents with reduced mean channel open time and suggested to directly interact with the channel pore at the extracellular side of the membrane. Displays minimal effects on P-glycoprotein and non-CFTR-mediated Cl- currents, and is effective in nasal and intestinal epithelia in vivo. Also available as a 25 mM solution in DMSO (Cat. No. 219675). 包装 5 mg in Plastic ampoule 生化/生理作用 Cell permeable: yes 警告 Toxicity: Standard Handling (A) 重悬 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 其他说明 Sonawane, N.D., et al. 2006. FASEB J.20, 130. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息
产品性质
安全信息
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| 219675 | Sigma-Aldrich | InSolution CFTR Inhibitor II, GlyH-101-CAS 328541-79-3-Calbiochem | 2950.71元/5 MG; | 咨询 | |||||||||||||||||||||||||||||||||
产品说明 一般描述 A cell-permeable glycinyl hydrazone compound that acts as a potent, selective and reversible open-channel blocker of CFTR with intermediate speed (<1 min; 95% inhibition at 50 µM; Ki = 4.3 µM in CFTR-expressing FRT cells for apical membrane Cl- current) and exhibits desirable aqueous solubility. Shown to produce inwardly rectifying CFTR Cl- currents with reduced mean channel open time and suggested to directly interact with the channel pore at the extracellular side of the membrane. Displays minimal effects on P-glycoprotein and non-CFTR-mediated Cl- currents, and is effective in nasal and intestinal epithelia in vivo. 包装 5 mg in Glass bottle 生化/生理作用 Cell permeable: yes 警告 Toxicity: Irritant (B) 外形 A 25 mM (5 mg/406 µL) solution of CFTR Inhibitor II, GlyH-101 (Cat. No. 219671) in DMSO. 重悬 Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 3 months at -70°C. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息
产品性质
安全信息
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