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CAS: 328-50-7
分子式: C5H6O5
分子量: 146.10
熔点: 113-115℃
中文名称: 
alpha-酮戊二酸
α-酮基戊二酸
alpha-羰基戊二酸
2-酮戊二酸
2-氧代戊二酸
α-酮戊二酸
2-氧代-1,5-戊二酸
英文名称: 
2-oxo-Pentanedioic acid
alpha-ketoglutaric acid
2-oxo-pentanedioic aci
2-ketoglutaric acid
α-Ketoglutaric acid
Pentanedioic acid,2-oxo-
-Ketoglutaric acid
2-Oxpentanedioic acid
2-Oxoglutaric acid
2-Oxo-1,5-pentanedioic acid
性质描述: 白色细结晶性粉末。熔点113.5℃。易溶于水、醇、极难溶于醚,久贮变淡灰黄色,易潮解。
生产方法: 将225g草酰琥珀酸三乙酯与600ml浓盐酸混合,放置过液。蒸馏浓缩至140℃,剩余物冷却结晶,得α-酮基戊二酸110-112g,收率92-93%。
用途: 测定氨基转换酶及脱氢酶的底物,测定肝功能的配套试剂,也用作有机合成中间体。
推荐供应商

基本信息

货号品牌产品名称规格包装、参考价格
K812223MACKLINα-酮戊二酸98%30元/25g;   80元/100g;   299元/500g;   1251元/2.5kg;   咨询
储存:2~8°C
状态:白色到黄色粉末或晶体
K794537MACKLINα-酮戊二酸10mM in DMSO437元/1ml;   咨询
储存:-20°C
K0005TCI2-Oxoglutaric Acid>99.0%(T)220元/25G;   600元/100G;   1685元/500G;   咨询

基本信息

纯度/分析方法>99.0%(T)
分子式/分子量C5H6O5 = 146.10
外观与形状(20℃)固体
Reaxys-RN1705689
PubChem物质ID87571945
SDBS (AIST Spectral DB)1092
Merck Index (14)5303
MDL编号MFCD00004165

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(GC)min. 95.0 %
Purity(Neutralization titration)min. 99.0 %
Melting point113.0 to 117.0 ℃
Solubility in Wateralmost transparency

物性(参考值)

熔点116 ℃
水溶性完全溶解
溶解性(易溶于)
溶解度(极微溶)乙醚

安全信息

图形或危害标志
信号词危险
危险性说明H318 : 造成严重眼损伤。
防范说明P280 : 戴防护眼罩/戴防护面具。
P305 + P351 + P338 + P310 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。立即呼叫急救中心/医生。

相关法规

RTECS#SA0454200
239270J&Kα-Ketoglutaric acid99%132元/25G;   374元/100G;   1211元/500G;   咨询

基本信息

分子式C5H6O5
分子量146.10
熔点114-117
MDL编码MFCD00004165
Beilstein1705689
Merck14,5303
EINECS 编号206-330-3
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Danger
危险说明H315
H318
H335
防范说明P261
P280
P305+P351+P338
WGK3
A10256Alfa Aesar2-Ketoglutaric Acid98%385元/25g;   883元/100g;   3969元/500g;   咨询

应用
2-Ketoglutaric acid is used as an intermediate in the kreb?’s cycle catalyzed by glutamate dehydrogenase enzyme on glutamate. It is also used in dietary supplements to improve protein synthesis.

备注
Store away from heat store in inert gas Store away from strong oxidizing agents. keep container tightly closed. Store in cool, dry conditions in well sealed containers.

基本信息

MDL
MFCD00004165

EINECS
206-330-3

分子式
C5H6O5

分子量
146.10

熔点
113-117°

灵敏度
Keep Cold.

形态
Crystalline powder

溶解性
Soluble in water, methanol and dimethyl sulfoxide.

Beilstein
1705689

Merck
14,5303

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

TSCA

C12286Alfa Aesar2-Ketoglutaric Acid98%434元/25g;   933元/100g;   3000元/500g;   咨询

基本信息

Ref#
12286

MDL
4165

分子式
C5 H6 O5

分子量
146.1

O3348-100Alfa AesarA-KETOGLUTARIC ACID REAG 100G1068元/100g;   咨询

基本信息

Ref#
F53803

1.05194Millipore2-Oxoglutaric Acidfor biochemistry507.2元/25 G;   862.98元/100 G;   3775.35元/1 KG;   咨询

产品说明

一般描述

for biochemistry

应用

2-Oxoglutaric acid for biochemistry. CAS 328-50-7, pH 1.5 (50 g/l, H₂O, 20 °C).

分析说明

Assay99.0 - 101.0 %
Identitypasses test
Melting range112 - 115 °C
As (Arsenic)≤ 1 ppm
Fe (Iron)≤ 30 ppm
分子量146.09
MDL编号MFCD00004165
EC索引号206-330-3

产品性质

质量水平100
形式solid
pH值(酸碱度)1.5 (20 ℃, 50 g/L in H2O)
mp112-116 ℃
堆积密度800 kg/m3
储存温度2-8℃
InChI1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChI keyKPGXRSRHYNQIFN-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H318
预防措施声明P280 - P305 + P351 + P338
危险分类Eye Dam. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
K1128Sigma-Aldrichα-Ketoglutaric acidBioReagent, suitable for cell culture, suitable for insect cell culture637.21元/5 G;   851.38元/25 G;   1748.28元/100 G;   咨询

产品说明

应用

TCA(三羧酸循环)分子,用作昆虫和哺乳动物细胞培养中的补充剂。

基本信息

线性分子式HOOCCH2CH2COCOOH
分子量146.10
Beilstein1705689
EC 号206-330-3
MDL编号MFCD00004165
PubChem化学物质编号24896202
NACRESNA.32

产品性质

质量水平200
产品线BioReagent
测定≥98.5% NaOH basis (titration)
形式powder or crystals
technique(s)cell culture | insect: suitable
cell culture | mammalian: suitable
溶解性water: 100 mg/mL, clear to slightly hazy, colorless to almost colorless
web metadata keyword.defaultTCA cycle metabolite
储存温度2-8℃
SMILES stringOC(=O)CCC(=O)C(O)=O
InChI1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChI keyKPGXRSRHYNQIFN-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H318
预防措施声明P280 - P305 + P351 + P338 + P310
危险分类Eye Dam. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
K1750Sigma-Aldrichα-Ketoglutaric acid≥98.5% (NaOH, titration)1334.26元/100 G;   6574.35元/1 KG;   咨询

产品说明

一般描述

α-Ketoglutaric acid (α-KG) is produced in the tricarboxylic acid cycle.

应用

α-Ketoglutaric acid (α-KG) has been used:


包装

100 g in poly bottle
1 kg in poly bottle

生化/生理作用

α-Ketoglutaric acid (α-KG) has a wide range of applications in the animal feed, food, pharmaceutical and fine chemistry industries.

基本信息

线性分子式HOOCCH2CH2COCOOH
分子量146.10
Beilstein1705689
EC 号206-330-3
MDL编号MFCD00004165
PubChem化学物质编号57654314
NACRESNA.32

产品性质

质量水平200
测定≥98.5% (NaOH, titration)
形式powder
溶解性water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
储存温度2-8℃
SMILES stringOC(=O)CCC(=O)C(O)=O
InChI1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChI keyKPGXRSRHYNQIFN-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H318
预防措施声明P280 - P305 + P351 + P338 + P310
危险分类Eye Dam. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
75890Sigma-Aldrichα-Ketoglutaric acid99.0-101.0% (T)602.35元/25 G;   1496.45元/100 G;   2203.43元/500 G;   咨询

产品说明

一般描述

α-酮戊二酸是一种2-氧代羧酸(2-OCA),其在Kreb循环中作为代谢物产生。

应用

α-酮戊二酸与 L-精氨酸可以用氰基硼氢化钠还原形成非对映异构体:胭脂碱和异吲哚。

其他说明

分析色氨酸的试剂;谷氨酸脱氢酶的底物

基本信息

线性分子式HOOCCH2CH2COCOOH
分子量146.10
Beilstein1705689
EC 号206-330-3
MDL编号MFCD00004165
PubChem化学物质编号329766750
NACRESNA.22

产品性质

质量水平300
测定99.0-101.0% (T)
mp114-118 ℃
溶解性H2O: 1 g/10 mL, clear to slightly hazy, colorless to almost colorless
储存温度2-8℃
SMILES stringOC(=O)CCC(=O)C(O)=O
InChI1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChI keyKPGXRSRHYNQIFN-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H318
预防措施声明P280 - P305 + P351 + P338 + P310
危险分类Eye Dam. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
61234Supelcoα-Ketoglutaric acidanalytical standard948.64元/10 MG;   2327.31元/50 MG;   咨询

产品说明

一般描述

α-Ketoglutaric acid, an α-ketoacid, is identified as a potential, renal cell carcinoma (RCC) biomarker via urinary metabolomic profiling. It plays an important role in living beings as an angiogenesis suppressor.

应用

α-Ketoglutaric acid may be used as an analytical reference standard for the quantification of the analyte in the following:


基本信息

线性分子式HOOCCH2CH2COCOOH
分子量146.10
Beilstein1705689
EC 号206-330-3
MDL编号MFCD00004165

产品性质

等级analytical standard
测定99.0-101.0% (T)
保质期limited shelf life, expiry date on the label
application(s)clinical testing
格式neat
储存温度2-8℃
SMILES stringOC(=O)CCC(=O)C(O)=O
InChI1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChI keyKPGXRSRHYNQIFN-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H318
预防措施声明P280 - P305 + P351 + P338 + P310
危险分类Eye Dam. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
453795Amethystα-Ketoglutaric acid99%, 试剂级53元/25G;   100元/100G;   383元/500G;   咨询

基本信息

分子式C5H6O5
分子量146.10
熔点114-117
MDL编码MFCD00004165
Beilstein1705689
Merck14,5303
EINECS 编号206-330-3
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Danger
危险说明H315
H318
H335
防范说明P261
P280
P305+P351+P338
WGK3
069250Fluorochem2-Oxopentanedioic acid98%440元/100g;   858元/250g;   2244元/1kg;   8140元/5kg;   咨询

基本信息

CAS Number328-50-7
MDL NumberMFCD00004165
Melting Point114-117℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H318: Causes serious eye damage.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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