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CAS: 300853-81-0
中文名称: 
ptp-β human
protein tyrosine phosphatase-β
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货号品牌产品名称规格包装、参考价格详情
P9864Sigma-AldrichPTP-β human≥90%, recombinant, expressed in E. coli K12, GST-tagged, buffered aqueous glycerol solution, ≥50,000 units/mg protein8261.12元/10000 UNITS;   展开

产品说明

一般描述

Protein tyrosine phosphatase, receptor type B (PTPRB), also known as vascular endothelial-protein-tyrosine phosphatase (VE-PTP), might have a role in remodeling of blood vessels and in angiogenesis. The gene encoding it is localized on human chromosome 12q15. It is also important for endothelial cell migration. The protein also controls the phosphorylation state of the angiopoietin receptor, Tie-2. PTPRB may modulate sodium channels by influencing the tyrosine phosphorylation status.

生化/生理作用

Dephosphorylates tyrosine proteins.

单位定义

One unit of PTP-β will hydrolyze 1.0 nanomole of p-nitrophenyl phosphate per min at 30 ℃.

外形

solution in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCL, 3 mM DTT, 16 mM glutathione and 20% glycerol

基本信息

MDL编号MFCD02688688
NACRESNA.32

产品性质

质量水平200
生物来源human
重组expressed in E. coli K12
测定≥90%
形式buffered aqueous glycerol solution
specific activity≥50,000 units/mg protein
分子量 ~250 kDa
UniProt登记号P23467
application(s)cell analysis
运输dry ice
储存温度−70℃
Gene Informationhuman ... PTPRB(5787)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
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