| CAS: | 298684-44-3 | |
| 分子式: | C14H14ClNO2S | |
| 分子量: | 295.78 | |
| 英文名称: |
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| 用途: | ML402 是选择性的 TREK-1 激活剂。 |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||||
| M879745 | MACKLIN | ML402 | ≥99% | 170元/1mg; 483元/5mg; | 咨询 | ||||||||||||||||||||||||||||||
储存：2-8℃ | |||||||||||||||||||||||||||||||||||
| SML2780 | Sigma-Aldrich | ML402 | ≥98% (HPLC) | 940.27元/5 MG; 3897.56元/25 MG; | 咨询 | ||||||||||||||||||||||||||||||
产品说明 生化/生理作用 ML402 is a selective activator of K2P2.1 (TREK-1) and K2P10.1 (TREK-2) potassium channels. It was used to determine a cryptic selectivity filter binding site of the K2P2.1 (TREK-1) channel, designated the K2P modulator pocket. This binding pocket stabilizes an active "leak-mode" conformation, binding small-molecule activators that restrict the mobility of the selectivity filter and surrounding structure. 基本信息
产品性质
安全信息
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