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CAS: 2986-17-6
分子式: C7H16N2S
分子量: 160.28
熔点: 143-145℃
中文名称: 
二异丙基硫脲
N,N'-二异丙基硫脲
英文名称: 
N,N'-bis(1-methylethyl)-Thiourea
1,3-diisopropyl-2-thio-ure
1,3-diisopropylthiourea
diisopropyl thiourea
n,n'-bis(1-methylethyl)thiourea
n,n'-diisopropylthiourea
n,n'-bis(1-methylethyl)-thioure
1,3-diisopropyl-2-thiourea
Thiourea,N,N'-bis(1-methylethyl)-
性质描述: 该品熔点141℃,溶于氯仿。
生产方法: 由异丙胺(75-31-0)经加成、缩合、胺化而得。将氢氧化钠溶液和二硫化碳,混合冷至5℃,滴加异丙胺,约半小时加完,温度控制在25℃以下。搅拌半小时后缓缓升温至70℃,反应1h。冷至40℃时开始滴加氯甲酸乙酯(541-41-3),约1h加完,再加热至75℃,反应15min。冷至50℃以上,用活性炭处理。静置分层,分取油层于15℃以下滴加到异丙胺和水的混合液中。然后加热至55℃反应15min,再冷至10℃以下过滤,水洗得粗品。粗品用乙醇重结晶、活性炭脱色,在60℃干燥,得二异丙基硫脲。收率约50%。
用途: 该品为抗菌素类药物硫脒头孢菌素的中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
D0253TCI1,3-Diisopropylthiourea>99.0%(N)390元/25G;   展开

基本信息

纯度/分析方法>99.0%(N)
分子式/分子量C7H16N2S = 160.28
外观与形状(20℃)固体
Reaxys-RN605861
PubChem物质ID87566957
SDBS (AIST Spectral DB)1403
MDL编号MFCD00040485

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(with Total Nitrogen)min. 99.0 %
Melting point143.0 to 146.0 ℃

物性(参考值)

熔点144 ℃
溶解性(可溶于)甲醇

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#YS9860000
393053J&K1,3-Diisopropyl-2-thiourea98%131元/25G;   431元/100G;   展开

基本信息

分子式C7H16N2S
分子量160.28
熔点143-145
MDL编码MFCD00040485
EINECS 编号221-051-7

安全信息

图形或危害标志
提示语Danger
危险说明H302
H311
H331
防范说明P301+P312
P330
WGK3
RTECSYS9860000
D126802Sigma-Aldrich1,3-Diisopropyl-2-thiourea99%925.02元/100 G;   展开

基本信息

线性分子式(CH3)2CHNHCSNHCH(CH3)2
分子量160.28
EC 号221-051-7
MDL编号MFCD00040485
PubChem化学物质编号24893393
NACRESNA.22

产品性质

质量水平100
测定99%
mp143-145 ℃ (lit.)
SMILES stringCC(C)NC(=S)NC(C)C
InChI1S/C7H16N2S/c1-5(2)8-7(10)9-6(3)4/h5-6H,1-4H3,(H2,8,9,10)
InChI keyKREOCUNMMFZOOS-UHFFFAOYSA-N
Gene Informationhuman ... EPHX2(2053)
mouse ... Ephx2(13850)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P301 + P312 + P330
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
018562Fluorochem1,3-Diisopropyl-2-thiourea99%220元/1g;   550元/5g;   968元/25g;   展开

基本信息

CAS Number2986-17-6
MDL NumberMFCD00040485
Melting Point142-148℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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