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CAS: 298-93-1
分子式: C18H16N5S·Br
分子量: 414.32
熔点: 195℃
中文名称: 
2-(4,5-二甲基-2-噻唑基)-3,5-二苯基-2H-四唑氢溴酸盐
英文名称: 
2H-Tetrazolium,2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-,bromide
2H-Tetrazolium, 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2h-tetrazoliu bromide
2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-2h-tetrazoliu bromide
3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide
methylthiazoletetrazolium
mmt tetrazolium
thiazolyl blue
thiazolyl blue monotetrazolium
thiazolyl blue tetrazolium bromide
mtt
展开更多英文名
推荐供应商
货号品牌产品名称规格包装、参考价格详情
T794579MACKLIN噻唑兰10mM in DMSO185元/1ml;   展开
储存：-20°C

性质 

状态：黑色粉末

厚度：100-200nm

纯度：约54-68 wt%

主要成分：Ti3C2

片径:2-10um

T818538MACKLIN噻唑兰98%48元/250mg;   79元/1g;   281元/5g;   1190元/25g;   3840元/100g;   展开
储存：2~8°C
状态：黄色到暗黄色粉末

性质 

状态：黑色粉末

厚度：100-200nm

纯度：约54-68 wt%

主要成分：Ti3C2

片径:2-10um

T6126MACKLIN噻唑兰>99.0% 生物技术级149元/1g;   538元/5g;   1734元/25g;   4754元/100g;   展开
储存：2~8°C
状态：淡黄色到黄色粉末

性质 

状态：黑色粉末

厚度：100-200nm

纯度：约54-68 wt%

主要成分：Ti3C2

片径:2-10um

D0801TCI3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium Bromide>98.0%(T)695元/1G;   1995元/5G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C18H16BrN5S = 414.33
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况光,湿气 (吸湿)
相关CAS RN2348-71-2
Reaxys-RN3825277
PubChem物质ID87567423
SDBS (AIST Spectral DB)10829
MDL编号MFCD00011964

技术规格

AppearanceLight yellow to Brown powder to crystal
Purity(HPLC)min. 97.0 area%
Purity(Nonaqueous Titration)min. 98.0 %
Solubility in hot Wateralmost transparency
Drying lossmax. 1.0 %
SensitivenessColorimetric Test : Turn Red purple with 35ppm D-Glucose

物性(参考值)

熔点195 ℃(dec.)
最大吸收波长380(H2O) nm
水溶性微溶
在水中的溶解度10,000 mg/l  
溶解性(微溶于)乙醇

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H341 : 怀疑可造成遗传性缺陷。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P308 + P313 : 如接触到或有疑虑：求医/就诊。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
P405 : 存放处须加锁。

相关法规

RTECS#XF8060000
M3297TCIMTT [for Biochemical Research]>97.0%(HPLC)290元/200MG;   990元/1G;   展开

基本信息

纯度/分析方法>97.0%(HPLC)
分子式/分子量C18H16BrN5S = 414.33
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况光,湿气 (吸湿)
Reaxys-RN3825277
SDBS (AIST Spectral DB)10829
MDL编号MFCD00011964

技术规格

AppearanceLight yellow to Brown powder to crystal
Purity(HPLC)min. 97.0 area%
Purity(Nonaqueous Titration)min. 98.0 %
Functionality testto pass test (by Abs method)
SensitivenessColorimetric Test : Turn Red purple with 35ppm D-Glucose

物性(参考值)

熔点195 ℃(dec.)
最大吸收波长380(H2O) nm
水溶性微溶
在水中的溶解度10,000 mg/l  
溶解性(微溶于)乙醇

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H341 : 怀疑可造成遗传性缺陷。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P308 + P313 : 如接触到或有疑虑：求医/就诊。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
P405 : 存放处须加锁。

相关法规

RTECS#XF8060000
468941J&K3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide98%113元/250MG;   374元/1G;   1142元/5G;   展开

基本信息

分子式C18H16BrN5S
分子量414.32
熔点195
MDL编码MFCD00011964
Beilstein4081397
EINECS 编号206-069-5
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
H341
防范说明P261
P281
P305+P351+P338
WGK3
RTECSXF8060000
TSCA是
L11939Alfa AesarThiazolyl Blue Tetrazolium Bromide98%521元/1g;   1930元/5g;   展开

应用
Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

备注
Light, air and moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00011964

EINECS
206-069-5

分子式
C18H16BrN5S

分子量
414.33

熔点
ca 195° dec.

灵敏度
Moisture Sensitive. Air Sensitive. Light Sensitive. Store under Nitrogen. Ambient temperatures.

形态
Powder

溶解性
Soluble in water, ethanol, 2-methoxyethanol and phosphate buffered saline.

Beilstein
3825277

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

RTECS
XF8060000

TSCA
是

1.11714Millipore3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromidefor biochemistry1914.19元/1 G;   17053.9元/10 G;   展开

产品说明

分析说明

Assay (argentometric): ≥ 98
Identity (IR-spectrum): passes test
Spec. Absorptivity A 1%/1cm (242 nm; 0.001 %; 1 cm; methanol): 480 - 530
Heavy metals (as Pb): ≤ 0.001 %
Sulfated ash: ≤ 0.5 %

基本信息

经验(实验)分子式C18H16BrN5S
分子量414.32
MDL编号MFCD00011964
EC索引号206-069-5

产品性质

质量水平100
mp195 ℃
溶解性 10 g/L
储存温度2-30℃
InChI1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
InChI keyAZKSAVLVSZKNRD-UHFFFAOYSA-M

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H315 - H319 - H335 - H341
预防措施声明P201 - P202 - P261 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
475989Sigma-AldrichMTT-CAS 298-93-1-CalbiochemMembrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan.1272.64元/1 G;   8825.66元/10 G;   展开

产品说明

一般描述

Membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT-formazan. Spectrophotometric measurement of MTT-formazan at 540 or 570 nm allows quantitation of cell viability. Used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. An electron acceptor used for studying NADP-dependent dehydrogenases.

包装

1 g in Glass bottle
10 g in Plastic ampoule

生化/生理作用

Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
Used as a direct indicator of cytotoxicity and apoptosis.

警告

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

重悬

Following reconstitution, aliquot and freeze (-20°C.). Stock solutions are stable for up to 1 month at -20°C.

其他说明

Liu, Y., et al. 1997. J. Neurochem.69, 581.
Abdallah, M.A. 1980. Eur. J. Biochem. 112, 331.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C18H16BrN5S
分子量414.32
MDL编号MFCD00011964

产品性质

质量水平100
测定≥98% (silver nitrate titration)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
杂质≤0.5% Sulfated ash
颜色 yellow
溶解性PBS: 2 mg/mL
痕量阳离子heavy metals: ≤0.001%
运输ambient
储存温度15-25℃
InChI1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
InChI keyAZKSAVLVSZKNRD-UHFFFAOYSA-M

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H315 - H319 - H335 - H341
预防措施声明P201 - P202 - P261 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
M5655Sigma-AldrichThiazolyl Blue Tetrazolium Bromidepowder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97.5% (HPLC)354.82元/100 MG;   849.76元/500 MG;   1988.8元/1 G;   7872.71元/5 X 1 G;   展开

产品说明

应用

噻唑蓝溴化四唑已在细胞活力测定(MTT测定)中被用作比色代谢活性指示剂。它还被用于测定细胞增殖。
噻唑蓝四唑蓝(MTT)可用于细胞增殖的检测。 MTT产生一种淡黄色的溶液，通过活细胞的线粒体脱氢酶将其转化为深蓝色、不溶于水的MTT福尔马赞。该蓝色晶体可溶于酸化异丙醇，可采用比色法测定其570 nm处的强度。MTT已被用作组织化学/细胞化学试剂 以及用于检测NAD。 由于所使用的氰化物陷阱可与阳离子结合，组织中的ADP-连接酶系统无法采用MTT检测。 MTT迅速还原为福尔马赞，福尔马赞与镍、铜和钴螯合;钴螯合物已可用于氧化体系。

包装

1 g in glass bottle
15 mg in poly bottle
100, 500 mg in glass insert

基本信息

经验(实验)分子式C18H16BrN5S
分子量414.32
Beilstein4081397
EC 号206-069-5
MDL编号MFCD00011964
PubChem化学物质编号24897030
NACRESNA.75

产品性质

质量水平200
产品线BioReagent
测定≥97.5% (HPLC)
形式powder
technique(s)cell culture | insect: suitable
cell culture | mammalian: suitable
mp195 ℃ (dec.) (lit.)
溶解性H2O: 5 mg/mL
web metadata keyword.defaultcomponent of cytotoxicity kits, cell viability assay substrate
储存温度2-8℃
SMILES string[Br-].Cc1nc(sc1C)-[n+]2nc(nn2-c3ccccc3)-c4ccccc4
InChI1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
InChI keyAZKSAVLVSZKNRD-UHFFFAOYSA-M

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H315 - H319 - H335 - H341
预防措施声明P201 - P202 - P261 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
M2128Sigma-AldrichThiazolyl Blue Tetrazolium Bromide98%335.35元/100 MG;   539.04元/250 MG;   615.84元/500 MG;   929.57元/1 G;   2370.95元/5 G;   3804.98元/10 G;   展开

产品说明

应用

噻唑蓝四唑蓝(MTT)可用于细胞增殖的检测。 MTT产生一种淡黄色的溶液，通过活细胞的线粒体脱氢酶将其转化为深蓝色、不溶于水的MTT福尔马赞。该蓝色晶体可溶于酸化异丙醇，可采用比色法测定其570 nm处的强度。MTT已被用作组织化学/细胞化学试剂 以及用于检测NAD。 由于所使用的氰化物陷阱可与阳离子结合，组织中的ADP-连接酶系统无法采用MTT检测。 MTT迅速还原为福尔马赞，福尔马赞与镍、铜和钴螯合;钴螯合物已可用于氧化体系。
噻唑蓝四唑溴化物已用于以下检测：

  • 增殖检测。
  • TNF(肿瘤坏死因子)生物检测。

包装

1, 5, 10 g in glass bottle
100, 250 mg in glass insert
500 mg in glass bottle

基本信息

经验(实验)分子式C18H16BrN5S
分子量414.32
Beilstein4081397
EC 号206-069-5
MDL编号MFCD00011964
PubChem化学物质编号24896603
NACRESNA.47

产品性质

质量水平200
测定98%
形式powder
mp195 ℃ (dec.) (lit.)
溶解性2-methoxyethanol: soluble 20 mg/mL
ethanol: soluble 20 mg/mL
H2O: 5 mg/mL
web metadata keyword.defaultnitroblue tetrazolium, thiazolyl blue, tetrazolium blue, formazan,
application(s)diagnostic assay manufacturing
hematology
histology
储存温度2-8℃
SMILES string[Br-].Cc1nc(sc1C)-[n+]2nc(nn2-c3ccccc3)-c4ccccc4
InChI1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
InChI keyAZKSAVLVSZKNRD-UHFFFAOYSA-M

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H315 - H319 - H335 - H341
预防措施声明P201 - P202 - P261 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
V900888Sigma-AldrichThiazolyl Blue Tetrazolium BromideVetec™, reagent grade, 98%238.42元/250 MG;   669.2元/1 G;   展开

产品说明

应用

噻唑蓝四唑蓝(MTT)可用于细胞增殖的检测。 MTT产生一种淡黄色的溶液，通过活细胞的线粒体脱氢酶将其转化为深蓝色、不溶于水的MTT福尔马赞。该蓝色晶体可溶于酸化异丙醇，可采用比色法测定其570 nm处的强度。MTT已被用作组织化学/细胞化学试剂 以及用于检测NAD。 由于所使用的氰化物陷阱可与阳离子结合，组织中的ADP-连接酶系统无法采用MTT检测。 MTT迅速还原为福尔马赞，福尔马赞与镍、铜和钴螯合;钴螯合物已可用于氧化体系。

包装

1 g in glass bottle
250 mg in glass bottle

法律信息

Vetec is a trademark of sigma-aldrich International GmbH

基本信息

经验(实验)分子式C18H16BrN5S
分子量414.32
Beilstein4081397
EC 号206-069-5
MDL编号MFCD00011964
PubChem化学物质编号329830220

产品性质

等级reagent grade
产品线Vetec™
测定98%
形式powder
mp195 ℃ (dec.) (lit.)
溶解性H2O: 5 mg/mL, clear
适用性suitable for
application(s)diagnostic assay manufacturing
hematology
histology
储存温度2-8℃
SMILES string[Br-].Cc1nc(sc1C)-[n+]2nc(nn2-c3ccccc3)-c4ccccc4
InChI1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
InChI keyAZKSAVLVSZKNRD-UHFFFAOYSA-M

安全信息

象形图GHS07GHS08
警示用语：Warning
危险声明H315 - H319 - H335 - H341
预防措施声明P261 - P281 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
991008Amethyst3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide98%, 试剂级47元/250MG;   111元/1G;   310元/5G;   1252元/25G;   展开

基本信息

分子式C18H16BrN5S
分子量414.32
熔点195
MDL编码MFCD00011964
Beilstein4081397
EINECS 编号206-069-5
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
H341
防范说明P261
P281
P305+P351+P338
WGK3
RTECSXF8060000
TSCA是
047891FluorochemMethylthiazolyldiphenyl-tetrazolium bromide98%682元/1g;   2002元/5g;   3564元/10g;   7678元/25g;   展开

基本信息

CAS Number298-93-1
MDL NumberMFCD00011964
Melting Point195℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
H341: Suspected of causing genetic defects ..
防范说明 P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P281: Use personal protective equipment as required.
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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