[登录] [免费注册]
试剂仪器网
位置:首页 > 资料中心 > 化工字典 > 298-81-7
关键词:       仅模糊查询
CAS: 298-81-7
分子式: C12H8O4
分子量: 216.19
熔点: 143-148℃
中文名称: 
8-甲氧基补骨脂素
甲氧基补骨脂素
黄原毒
黄原毒素
花椒毒素
6-羟基-7-甲氧基苯并呋喃-5-丙烯酸-δ-内酯
氧化补骨脂素
8-甲氧基补骨酯
英文名称: 
9-Methoxy-furo[3,2-g]chromen-7-one
7H-Furo[3,2-g][1]benzopyran-7-one,9-methoxy-
5-Benzofuranacrylic acid,6-hydroxy-7-methoxy-,δ-lactone
8-Methoxy-6,7-furanocoumarin
Puvalen
Puvamet
Uvadex
9-methoxyfuro[3,2-g]chromen-7-one
9-Methoxyfuro[3,2-g]chromen-7-on
2-g)(1)benzopyran-7-one, 9-methoxy-7h-furo(
6-hydroxy-7-methoxy-5-benzofuranacrylic aci delta-lactone
6-hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone
2-g][1]benzopyran-7-one, 9-methoxy-7h-furo[
8-methoxy-(furano-3'.2':6.7-coumarin)
8-methoxy-2',3',6,7-furocoumarin
8-methoxy-4',5',6,7-furocoumarin
8-methoxy-4',5':6,7-furocoumarin
8-methoxy[furano-3',2':6,7-coumarin]
8-methoxypsoralen
8-methoxypsoralene
8-mop
8-mop capsules
8-mp
9-methoxy-7h-furo(3,2-g)(1)benzopyran-7-one
9-methoxy-7h-furo(3,2-g)benzopyran-7-one
9-methoxypsoralen
ammoidin
geroxalen
meladinin
meladinine
meladoxen
meloxine
methoxa-dome
methoxalen
methoxsalen
nci-c55903
new-meladinin
oxoralen-ultra
oxsoralan
oxsoralen
oxsoralen ultra
oxypsoralen
proralone-mop
psoralon-mop
xanthotoxin
xanthotoxine
展开更多英文名
用途: 治疗牛皮癣、白癫风。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
M861678MACKLIN8-甲氧基补骨脂素99.5%132元/1g;   498元/5g;   1198元/25g;   3926元/100g;   展开
储存:室温,干燥
状态:白色到黄色固体
M796913MACKLIN8-甲氧基补骨脂素10mM in DMSO106元/1ml;   展开
储存:-20°C
X0009TCIXanthotoxin>98.0%(GC)125元/100MG;   360元/1G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C12H8O4 = 216.19
外观与形状(20℃)固体
Reaxys-RN196453
PubChem物质ID87577878
SDBS (AIST Spectral DB)10625
Merck Index (14)5988
MDL编号MFCD00005009

技术规格

AppearanceWhite to Orange to Green powder to crystal
Purity(GC)min. 98.0 %
Melting point145.0 to 149.0 ℃
Solubility in hot EtOHvery faint turbidity

物性(参考值)

熔点147 ℃
水溶性不溶
溶解性(易溶于)氯仿
溶解性(可溶于)丙酮

安全信息

图形或危害标志
信号词危险
危险性说明H302 : 吞咽有害。
H371 : 可能损害器官。
H373 : 长期或反复接触可能损害器官。
H341 : 怀疑可造成遗传性缺陷。
H350 : 可能致癌。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P260 : 不要吸入粉尘/ 烟/ 气体/ 烟雾/ 蒸气/ 喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P308+P311 : 如接触到或有疑虑:呼叫急救中心/医生。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。

相关法规

RTECS#LV1400000
404254J&KXanthotoxin98%, CYP自噬抑制剂304元/1G;   1136元/5G;   4919元/25G;   展开

基本信息

分子式C12H8O4
分子量216.19
熔点143-148
MDL编码MFCD00005009
Beilstein196453
Merck14,5988
EINECS 编号206-066-9
存储条件Store at 2-8℃

安全信息

图形或危害标志
提示语Danger
危险说明H302
H341
H350
H371
H373
防范说明P201
P280
P301+P312
P301+P330+P331
P305+P351+P338
P308+P313
P310
UN号码3261
危险分类8
包装等级II
RTECSLV1400000
TSCA
A17108Alfa Aesar8-Methoxypsoralen99%777元/1g;   3378元/5g;   15461元/25g;   展开

应用
8-Methoxypsoralen, is used in Photochemotherapy (methoxsalen with long wave ultraviolet radiation) is indicated for the repigmentation of idiopathic vitiligo. It is also used in Photopheresis (methoxsalen with long wave ultraviolet radiation of white blood cells) is indicated for use with the UVAR* System in the palliative treatment of the skin manifestations of cutaneous T-cell lymphoma.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Stable under recommended storage conditions. Keep away from strong oxidizing agents.

基本信息

MDL
MFCD00005009

EINECS
206-066-9

分子式
C12H8O4

分子量
216.20

熔点
146-150°

灵敏度
Light Sensitive. Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in acetone, ethanol (slight), acetic acid, and chloroform (50 mg/ml). Insoluble in water.

Beilstein
196453

Merck
14,5988

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H317
Harmful if swallowed.May cause an allergic skin reaction.

Precautionary Statements
P261-P280g-P301+P312a-P321-P333+P313-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves.Wear protective gloves.Specific treatment (see label).If skin irritation or rash occurs: Get medical advice/attention.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
8

包装组
II

危险类别
22-43
Harmful if swallowed.May cause sensitization by skin contact.

安全等级
24-37-60
Avoid contact with skin.Avoid contact with skin.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

RTECS
LV1400000

TSCA

C21415Alfa Aesar8-Methoxypsoralen99%699元/1g;   2522元/5g;   展开

基本信息

Ref#
21415

MDL
5009

分子式
C12 H8 O4

分子量
216.19

安全信息

危险等级
8

包装组
II

1417001USPMethoxsalenUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

8-甲氧基补骨脂素 (8-MOP) 加 A 波紫外线 (UVA) 辐射可诱导单加合物形成和 DNA 链间交联,因此可用于研究 DNA 修复和重组机制。培养的正常人黑素细胞经 8-甲氧基补骨脂素处理和 A 波紫外线 (UVA) 照射后形成 8-甲氧基补骨脂素-磷脂光加成产物,经二酰甘油取代后可在无细胞体系中激活蛋白激酶 C。8-MOP 是纯化重组细胞色素 P450 的灭活剂。它还可以通过抑制 [Ca2+] 的升高,而抑制从 P 物质激活的大鼠腹膜肥大细胞的 P 物质诱导型组胺释放。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C12H8O4
分子量216.19
Beilstein196453
MDL编号MFCD00005009
PubChem化学物质编号329750415
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp148-150 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCOc1c2OC(=O)C=Cc2cc3ccoc13
InChI1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3
InChI keyQXKHYNVANLEOEG-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H317
预防措施声明P280 - P301 + P312 + P330
危险分类Acute Tox. 4 Oral - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHL89866Xanthotoxinphyproof® Reference Substance3048.57元/50 MG;   展开

产品说明

一般描述

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

生化/生理作用

8-甲氧基补骨脂素 (8-MOP) 加 A 波紫外线 (UVA) 辐射可诱导单加合物形成和 DNA 链间交联,因此可用于研究 DNA 修复和重组机制。培养的正常人黑素细胞经 8-甲氧基补骨脂素处理和 A 波紫外线 (UVA) 照射后形成 8-甲氧基补骨脂素-磷脂光加成产物,经二酰甘油取代后可在无细胞体系中激活蛋白激酶 C。8-MOP 是纯化重组细胞色素 P450 的灭活剂。它还可以通过抑制 [Ca2+] 的升高,而抑制从 P 物质激活的大鼠腹膜肥大细胞的 P 物质诱导型组胺释放。

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

基本信息

经验(实验)分子式C12H8O4
分子量216.19
Beilstein196453
MDL编号MFCD00005009

产品性质

等级primary reference standard
产品线phyproof® Reference Substance
测定≥95.0% (HPLC)
形式solid
manufacturer/tradenamePhytoLab
mp148-150 ℃ (lit.)
储存温度2-8℃
SMILES stringCOc1c2OC(=O)C=Cc2cc3ccoc13
InChI1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3
InChI keyQXKHYNVANLEOEG-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H317
预防措施声明P280 - P301 + P312 + P330 - P302 + P352
危险分类Acute Tox. 4 Oral - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHR3040SupelcoMethoxsalenpharmaceutical secondary standard, certified reference material1440.42元/500 mg;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

生化/生理作用

8-甲氧基补骨脂素 (8-MOP) 加 A 波紫外线 (UVA) 辐射可诱导单加合物形成和 DNA 链间交联,因此可用于研究 DNA 修复和重组机制。培养的正常人黑素细胞经 8-甲氧基补骨脂素处理和 A 波紫外线 (UVA) 照射后形成 8-甲氧基补骨脂素-磷脂光加成产物,经二酰甘油取代后可在无细胞体系中激活蛋白激酶 C。8-MOP 是纯化重组细胞色素 P450 的灭活剂。它还可以通过抑制 [Ca2+] 的升高,而抑制从 P 物质激活的大鼠腹膜肥大细胞的 P 物质诱导型组胺释放。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

基本信息

经验(实验)分子式C12H8O4
分子量216.19
Beilstein196453
MDL编号MFCD00005009

产品性质

等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 500 mg
mp148-150 ℃ (lit.)
application(s)pharmaceutical
药典可追溯性traceable to USP 1417001
储存温度2-30℃
SMILES stringCOc1c2OC(=O)C=Cc2cc3ccoc13
InChI1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3
InChI keyQXKHYNVANLEOEG-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H317
预防措施声明P261 - P264 - P270 - P280 - P301 + P312 - P302 + P352
危险分类Acute Tox. 4 Oral - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
239129Fluorochem9-Methoxy-7H-furo[3,2-g]chromen-7-one95%440元/1g;   1144元/5g;   1848元/10g;   3410元/25g;   展开

基本信息

CAS Number298-81-7
MDL NumberMFCD00005009
Melting Point143-150℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H332: Harmful if inhaled.
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H340: May cause genetic defects ..
H350: May cause cancer ..
H371: May cause damage to organs Nervous system..
H373: May cause damage to organs Thyroid gland. Kidney..
防范说明 P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P260: Do not breathe
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P281: Use personal protective equipment as required.
P285: In case of inadequate ventilation wear respiratory protection.
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P304 + P341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P308 + P313: IF exposed or concerned: Get medical advice/ attention.
P309: IF exposed or if you feel unwell: .
P309 + P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
P311: Call a POISON CENTER or doctor/physician.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P314: Get medical advice/attention if you feel unwell.
P330: Rinse mouth.
P342 + P311: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9