[登录] [免费注册]
试剂仪器网
位置:首页 > 资料中心 > 化工字典 > 296771-07-8
关键词:       仅模糊查询
CAS: 296771-07-8
分子式: C16H11ClN6OS
分子量: 370.82
英文名称: 
dcemm2
2-((5h-[1,2,4]triazino[5,6-b]indol-3-yl)thio)-n-(5-chloropyridin-2-yl)acetamide
n-(5-chloro-2-pyridinyl)-2-(5h-1,2,4-triazino[5,6-b]indol-3-ylthio)acetamide
推荐供应商
货号品牌产品名称规格包装、参考价格详情
H761455MACKLIN2-((5H-[1,2,4]三嗪并[5,6-b]吲哚-3-基)硫基)-N-(5-氯吡啶-2-基)乙酰胺95%1127元/10mg;   2250元/25mg;   3823元/50mg;   6498元/100mg;   展开
储存:2-8°C, 密封, 干燥
SML2990Sigma-AldrichdCeMM2≥98% (HPLC)3400.25元/25 MG;   展开

产品说明

生化/生理作用

dCeMM2 is a cell penetrant molecular glue degrader that induce ubiquitination and degradation of cyclin K by inciting an interaction of CDK12–cyclin K with a CRL4B ligase complex. dCeMM2 induced proximity between CDK12–cyclin K and the CRL complex adaptor protein DDB1 that causes ubiquitination and proteasomal degradation of cyclin K.

基本信息

经验(实验)分子式C16H11ClN6OS
分子量370.82

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度2-8℃
SMILES stringO=C(NC1=NC=C(Cl)C=C1)CSC2=NC3=C(C4=C(N3)C=CC=C4)N=N2
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9