| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 |
| C795682 | MACKLIN | 环吡酮胺 | 10mM in DMSO | 511元/1ml; | 展开 |
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| C857112 | MACKLIN | 环吡酮胺 | 99% | 69元/1g; 202元/5g; 679元/25g; 1694元/100g; | 展开 |
储存： -20°C 状态：白色到灰白色固体,粉末,或晶体 |
| C46343 | Alfa Aesar | Ciclopirox | | 1713元/1g; 6906元/5g; | 展开 |
基本信息 Ref#
46343 分子式
C12H17NO2 分子量
666.70 GHS危害和防范说明 Hazard Statements
H315 H319 H335 H341 Precautionary Statements
P302+P352 P337+P313 P304+P340 P280 P312 P332+P313 |
| Y0000040 | | Ciclopirox | European Pharmacopoeia (EP) Reference Standard | 1277.32元/ ; | 展开 |
产品说明 一般描述 This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. 包装 Unit quantity: 75 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue. 注意 Please find SDS provided by EDQM here.. 其他说明 Sales restrictions may apply. 基本信息 | 经验(实验)分子式 | C12H17NO2 | | 分子量 | 207.27 | | MDL编号 | MFCD00599441 | | NACRES | NA.24 |
产品性质 | 等级 | pharmaceutical primary standard | | manufacturer/tradename | EDQM | | application(s) | pharmaceutical (small molecule) | | 格式 | neat | | 储存温度 | 2-8℃ | | SMILES string | ON1C(C2CCCCC2)=CC(C)=CC1=O | | InChI | 1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3 | | InChI key | SCKYRAXSEDYPSA-UHFFFAOYSA-N |
安全信息 | 象形图 |  | | 警示用语： | Warning | | 危险声明 | H302 + H312 + H332 - H319 | | 预防措施声明 | P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 |
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| SML2011 | Sigma-Aldrich | Ciclopirox | ≥98% (HPLC) | 996.49元/50 MG; 1809.51元/100 MG; | 展开 |
产品说明 生化/生理作用 环吡酮是一种抗真菌和细胞可透过性的铁螯合剂。 研究发现它抑制多种酶和信号通路，包括脯氨酰羟化酶 2(PHD2)、真核翻译起始因子 5A(eIF5A)、Wnt/β-连环蛋白、低氧诱导因子-1α(HIF-1 α)/血管内皮生长因子( VEGF)、血管内皮生长因子受体 3(VEGFR-3)、雷帕霉素的哺乳动物靶标(mTOR)和细胞周期蛋白依赖性激酶(CDK)。 环吡酮除具有抗真菌活性外，还具有抗病毒和抗癌活性。 研究还表明，环吡酮以 p21 依赖性方式抵消糖尿病小鼠的糖毒性。
环吡酮是属于羟基吡啶酮类的化合物。研究发现它对皮肤癣菌、酵母、霉菌、某些细菌以及耐唑类念珠菌具有活性。与其他可抑制麦角固醇的抗真菌药不同，环吡酮具有不同的作用。它靶向降解真菌细胞过氧化物的金属依赖性酶。环吡酮的这种独特作用使得在病原真菌中抗药性几率较低。这种化合物用于指甲和皮肤特异性的局部配方。 基本信息 | 经验(实验)分子式 | C12H17NO2 | | 分子量 | 207.27 | | MDL编号 | MFCD00599441 | | NACRES | NA.77 |
产品性质 | 测定 | ≥98% (HPLC) | | 形式 | powder | | 颜色 | white to beige | | 溶解性 | DMSO: 2 mg/mL, clear | | 运输 | ambient | | 储存温度 | 2-8℃ | | SMILES string | ON1C(C2CCCCC2)=CC(C)=CC1=O | | InChI | 1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3 | | InChI key | SCKYRAXSEDYPSA-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 + H312 + H332 - H319 | | 预防措施声明 | P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 |
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| PHR1920 | Supelco | Ciclopirox | Pharmaceutical Secondary Standard; Certified Reference Material | 1980.79元/500 MG; | 展开 |
产品说明 一般描述 Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards 分析说明 These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. 其他说明 This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. 附注 To see an example of a Certificate of Analysis for this material enter LRAB0980 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. 基本信息 | 经验(实验)分子式 | C12H17NO2 | | 分子量 | 207.27 | | MDL编号 | MFCD00599441 |
产品性质 | 质量水平 | 300 | | 等级 | certified reference material
pharmaceutical secondary standard | | CofA | current certificate can be downloaded | | 包装 | pkg of 500 mg | | application(s) | pharmaceutical | | 格式 | neat | | 药典可追溯性 | traceable to PhEur Y0000040
traceable to USP 1134018 | | 储存温度 | 2-8℃ | | SMILES string | ON1C(C2CCCCC2)=CC(C)=CC1=O | | InChI | 1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3 | | InChI key | SCKYRAXSEDYPSA-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 + H312 + H332 - H319 | | 预防措施声明 | P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 |
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| 1134018 | USP | Ciclopirox | United States Pharmacopeia (USP) Reference Standard | 3231.47元/50 MG; | 展开 |
产品说明 一般描述 This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia. 分析说明 These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. 其他说明 Sales restrictions may apply. 基本信息 | 经验(实验)分子式 | C12H17NO2 | | 分子量 | 207.27 | | MDL编号 | MFCD00599441 | | NACRES | NA.24 |
产品性质 | 等级 | pharmaceutical primary standard | | manufacturer/tradename | USP | | application(s) | pharmaceutical (small molecule) | | 格式 | neat | | 储存温度 | 2-8℃ | | SMILES string | ON1C(C2CCCCC2)=CC(C)=CC1=O | | InChI | 1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3 | | InChI key | SCKYRAXSEDYPSA-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 + H312 + H332 - H319 | | 预防措施声明 | P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 516562 | Fluorochem | Ciclopirox | 0.97 | 220元/1g; 660元/5g; 1078元/10g; 2156元/25g; | 展开 |
基本信息 | CAS Number | 29342-05-0 | | MDL Number | MFCD00599441 |
安全信息 | 图形或危害标志 | | | 危险性说明 | H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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