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CAS: 28721-07-5
分子式: C15H12N2O
分子量: 252.27
熔点: 215-216°C
中文名称: 
奥卡西平
英文名称: 
f)azepine-5-carboxamide, 10,11-dihydro-10-oxo-5h-dibenz(
10,11-dihydro-10-oxo-5h-dibenz(b,f)azepine-5-carboxamide
gp 47680
oxacarbazepine
oxcarbazepine
Oxcarbazeping
用途: 神经系统用药。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
O815152MACKLIN10-氧代10,11-二氢-5H-二苯并[b,f]氮杂卓-5-甲酰胺98%36元/1g;   95元/5g;   300元/25g;   1028元/100g;   展开
储存:室温
状态:NA
O0363TCIOxcarbazepine>98.0%(HPLC)(N)290元/5G;   1090元/25G;   展开

基本信息

纯度/分析方法>98.0%(HPLC)(N)
分子式/分子量C15H12N2O2 = 252.27
外观与形状(20℃)固体
Reaxys-RN1474055
PubChem物质ID87561105
Merck Index (14)6929
MDL编号MFCD00865307

技术规格

AppearanceWhite to Light yellow to Light orange powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(with Total Nitrogen)min. 98.0 %

物性(参考值)

熔点216 ℃(dec.)
溶解性(可溶于)二甲基甲酰胺

相关法规

RTECS#HN8445000
H60014Alfa AesarOxcarbazepine98%4256元/250mg;   展开

应用
Oxcarbazepine is a sodium channel protein inhibitor. It is an anticonvulsant and mood-stab.

备注
Store at -20?°C.

基本信息

MDL
MFCD00865307

EINECS
249-188-8

分子式
C15H12N2O2

分子量
252.27

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Soluble in DMSO, methanol, water, ethanol and acetone.

安全信息

RTECS
HN8445000

TSCA

PHR1635SupelcoOxcarbazepinePharmaceutical Secondary Standard; Certified Reference Material2533.2元/1 G;   展开

产品说明

一般描述

用于质量控制的二级药物标准品为制药实验室和制造商制备内部工作标准品提供了一种方便、经济的替代方案。奥卡西平在结构上是卡马西平的衍生物,被广泛用作抗惊厥药、抗癫痫药和稳定情绪的药物。它主要用于治疗焦虑症、情绪障碍、癫痫和双相情感障碍。

应用

奥卡西平已被用作药物二级标准,用于使用分光光度法和高性能薄层色谱法测定药物制剂中的分析物。
这些二级标准品是合格的有证标准物质。它们适用用于于多种分析应用,包括但不限于药物释放检测、用于定性和定量分析的药物方法开发、食品和饮料质量控制检测以及其他校准要求。

生化/生理作用

抗惊厥药,止痛药。抑制藜芦碱诱导的递质释放。

分析说明

这些二级标准品可溯源到USP、EP和BP一级标准品。

其他说明

该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

附注

欲查看此物质的分析证书样本,请在下面的对话框中输入 LRAC1421。这只是一个示例证书,可能与您收到的批次不符。

基本信息

经验(实验)分子式C15H12N2O2
分子量252.27
EC 号249-188-8
MDL编号MFCD00865307
PubChem化学物质编号329823525
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 1 g
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to PhEur Y0001576
traceable to USP 1483152
储存温度2-8℃
SMILES stringO=C1CC2=C(C=CC=C2)N(C(N)=O)C3=CC=CC=C31
InChI1S/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19)
InChI keyCTRLABGOLIVAIY-UHFFFAOYSA-N
Gene Informationhuman ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
Y0001576OxcarbazepineEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

抗惊厥药,止痛药。抑制藜芦碱诱导的递质释放。

包装

Unit quantity: 120 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C15H12N2O2
分子量252.27
MDL编号MFCD00865307
PubChem化学物质编号329831491
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringO=C1CC2=C(C=CC=C2)N(C(N)=O)C3=CC=CC=C31
InChI1S/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19)
InChI keyCTRLABGOLIVAIY-UHFFFAOYSA-N
Gene Informationhuman ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
O3764Sigma-AldrichOxcarbazepine≥98% (HPLC), solid1827.11元/10 MG;   7050.8元/50 MG;   展开

产品说明

一般描述

奥卡西平(OXC)是卡马西平的酮类似物。与卡马西平不同,奥卡西平并没有副作用。它是一种具有抗癌作用的抗癫痫药。它相对于卡马西平具有药代动力学优势。它被指定用于神经性疼痛并可有效缓解三叉神经痛。OXC对其单羟基衍生物的分解代谢具有显著的药理特性。它可调节钾通道和电压依赖性钠通道。OXC能够调节收集小管中的V2受体-G蛋白复合物,并用于治疗尿崩症。

应用

奥卡西平已被用于人类癫痫性脑内皮细胞的反相高效液相色谱分析中。

包装

10, 50 mg in glass bottle

生化/生理作用

抗惊厥药,止痛药。抑制藜芦碱诱导的递质释放。

特点和优势

该化合物由 Novartis 开发。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单,请单击此处。

其他说明

斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDFO3764.pdf 中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息,请访问sigma.com/metlin。

基本信息

经验(实验)分子式C15H12N2O2
分子量252.27
EC 号249-188-8
MDL编号MFCD00865307
PubChem化学物质编号24724563
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
颜色 white
溶解性DMSO: ~9 mg/mL
创始人Novartis
SMILES stringO=C1CC2=C(C=CC=C2)N(C(N)=O)C3=CC=CC=C31
InChI1S/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19)
InChI keyCTRLABGOLIVAIY-UHFFFAOYSA-N
Gene Informationhuman ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)
rat ... Scnn1g(24768)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
1483152USPOxcarbazepineUnited States Pharmacopeia (USP) Reference Standard7401.92元/100 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

抗惊厥药,止痛药。抑制藜芦碱诱导的递质释放。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C15H12N2O2
分子量252.27
MDL编号MFCD00865307
PubChem化学物质编号329750633
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringO=C1CC2=C(C=CC=C2)N(C(N)=O)C3=CC=CC=C31
InChI1S/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19)
InChI keyCTRLABGOLIVAIY-UHFFFAOYSA-N
Gene Informationhuman ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
M06310FluorochemOxcarbazepine95%594元/1g;   1980元/5g;   5918元/25g;   展开

基本信息

CAS Number28721-07-5
MDL NumberMFCD00865307
Melting Point216℃ (dec.)

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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