| CAS: | 287118-97-2 | |||
| 分子式: | C16H13NO7 | |||
| 分子量: | 331.28 | |||
| 英文名称: |
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| 用途: | NCX 4040 is a nitric oxide-donating form of aspirin. NCX 4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX 4040 has been shown to induce apoptosis in several tumor cell lines. |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| N920681 | MACKLIN | 2-乙酰氧基苯甲酸4-硝基甲基苯基酯 | ≥98% (HPLC) | 1052元/5mg; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||||||
储存:−20°C 状态:固体 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
| SML0414 | Sigma-Aldrich | NCX 4040 | ≥98% (HPLC) | 1290.53元/5 MG; 4163.58元/25 MG; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||||||
产品说明 包装 5, 25 mg in glass bottle 生化/生理作用 NCX 4040 is a nitric oxide-donating form of aspirin. NCX 4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX 4040 has been shown to induce apoptosis in several tumor cell lines. 特点和优势 This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. 基本信息
产品性质
安全信息
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