[登录] [免费注册]
试剂仪器网
位置:首页 > 资料中心 > 化工字典 > 287118-97-2
关键词:       仅模糊查询
CAS: 287118-97-2
分子式: C16H13NO7
分子量: 331.28
英文名称: 
ncx 4040
2-(acetyloxy)benzoic acid 4-(nitroxymethyl)phenyl ester
no-aspirin
用途: NCX 4040 is a nitric oxide-donating form of aspirin. NCX 4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX 4040 has been shown to induce apoptosis in several tumor cell lines.
推荐供应商
货号品牌产品名称规格包装、参考价格详情
N920681MACKLIN2-乙酰氧基苯甲酸4-硝基甲基苯基酯≥98% (HPLC)1052元/5mg;   展开
储存:−20°C
状态:固体
SML0414Sigma-AldrichNCX 4040≥98% (HPLC)1290.53元/5 MG;   4163.58元/25 MG;   展开

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

NCX 4040 is a nitric oxide-donating form of aspirin. NCX 4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX 4040 has been shown to induce apoptosis in several tumor cell lines.

特点和优势

This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C16H13NO7
分子量331.28
MDL编号MFCD08062164
PubChem化学物质编号329825409
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
储存条件protect from light
颜色 white to beige
溶解性DMSO: 15 mg/mL (clear solution)
储存温度−20℃
SMILES stringCC(=O)Oc1ccccc1C(=O)Oc2ccc(CO[N+]([O-])=O)cc2
InChI1S/C16H13NO7/c1-11(18)23-15-5-3-2-4-14(15)16(19)24-13-8-6-12(7-9-13)10-22-17(20)21/h2-9H,10H2,1H3
InChI keyCTHNKWFUDCMLIQ-UHFFFAOYSA-N

安全信息

象形图GHS05GHS07GHS09
警示用语:Danger
危险声明H317 - H318 - H400
预防措施声明P273 - P280 - P302 + P352 - P305 + P351 + P338 + P310
危险分类Aquatic Acute 1 - Eye Dam. 1 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9