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CAS: 274901-16-5
英文名称: 
vildagliptin
(s)-1-(((1r,3r,5r,7s)-3-hydroxyadamantan-1-yl)glycyl)pyrrolidine-2-carbonitrile
推荐供应商
货号品牌产品名称规格包装、参考价格详情
904670J&KVildagliptin97%, DPP-4抑制剂1050元/10MG;   2986元/100MG;   展开

基本信息

分子式C17H25N3O2
分子量303.4
沸点531.3
闪点275.1
密度1.27
存储条件Freezer -20℃

安全信息

图形或危害标志
提示语Warning
危险说明H302
H410
防范说明P264
P270
P273
P301+P312
P330
P391
P501
UN号码3077
危险分类9
包装等级III
CDS022675Sigma-AldrichVildagliptin2562.52元/100 MG;   展开

产品说明

一般描述

Vildagliptin is an antidiabetic or antihyperglycemic agent. It improves glycemic control by inhibiting the dipeptidyl peptidase-4 (DPP-4) enzyme. It is also used in combination with metformin, pioglitazone, or insulin to lower the glycosylated hemoglobin (HbA1c) levels in type 2 diabetic patients.

其他说明

Please note that sigma-aldrich provides this product to early discovery researchers as part of a collection of unique chemicals. sigma-aldrich does not collect analytical data for this product. Buyer assumes responsibility to confirm product identity and/or purity. All sales are final.

NOTWITHSTANDING ANY CONTRARY PROVISION CONTAINED IN SIGMA-ALDRICH′S STANDARD TERMS AND CONDITIONS OF SALE OR AN AGREEMENT BETWEEN SIGMA-ALDRICH AND BUYER, SIGMA-ALDRICH SELLS THIS PRODUCT "AS-IS" AND MAKES NO REPRESENTATION OR WARRANTY WHATSOEVER WITH RESPECT TO THIS PRODUCT, INCLUDING ANY (A) WARRANTY OF MERCHANTABILITY, (B) WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE, OR (C) WARRANTY AGAINST INFRINGEMENT OF INTELLECTUAL PROPERTY RIGHTS OF A THIRD PARTY, WHETHER ARISING BY LAW, COURSE OF DEALING, COURSE OF PERFORMANCE, USAGE OF TRADE OR OTHERWISE.

基本信息

经验(实验)分子式C17H25N3O2
分子量303.40
MDL编号MFCD08275142
PubChem化学物质编号329795950

产品性质

描述AldrichCPR
SMILES stringN#C[C@H]1N(CCC1)C(CN[C@@](C[C@]2([H])C3)(C[C@@](C2)([H])C4)C[C@@]34O)=O
InChI1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12-,13+,14-,16+,17-/m0/s1
InChI keySYOKIDBDQMKNDQ-NHMCJKAESA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
SML2302Sigma-AldrichVildagliptin≥98% (HPLC)619.91元/50 MG;   3304.87元/250 MG;   展开

产品说明

生化/生理作用

Vildagliptin ia a selective inhibitor of dipeptidyl peptidase 4 (DPP4). This enzyme breaks down the incretins GLP-1 and GIP, gastrointestinal hormones that are released in response to a meal. By preventing GLP-1 and GIP inactivation, GLP-1 and GIP are able to potentiate the secretion of insulin and suppress the release of glucagon by the pancreas.

基本信息

经验(实验)分子式C17H25N3O2
分子量303.40
MDL编号MFCD08275142

产品性质

测定≥98% (HPLC)
形式powder
旋光性[α]/D -81 to -91°, c = 0.1 in methanol
颜色 white to beige
溶解性DMSO: 2 mg/mL, clear
储存温度2-8℃
SMILES stringN#C[C@H]1N(CCC1)C(CN[C@@](C[C@]2([H])C3)(C[C@@](C2)([H])C4)C[C@@]34O)=O
InChI1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12-,13+,14-,16+,17-/m0/s1
InChI keySYOKIDBDQMKNDQ-NHMCJKAESA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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