CAS 271246-66-3; mmk-1 trifluoroacetate

CAS:

271246-66-3

英文名称:

mmk-1 trifluoroacetate

l-methionine, l-leucyl-l--glutamyl-l-seryl-l-isoleucyl-l-phenylalanyl-l-arginyl-l-seryl-l-leucyl-l-leucyl-l-phenylalanyl-l-arginyl-l-valyl-

lesifrsllfrvm trifluoroacetate

gtpl6240

mmk-1 tfa

leu-glu-ser-ile-phe-arg-ser-leu-leu-phe-arg-val-met trifluoroacetate

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货号

品牌

产品名称

规格

包装、参考价格

详情

SML3075

Sigma-Aldrich

MMK-1 trifluoroacetate

≥95% (HPLC)

1480.38元/1 MG;

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产品说明

生化/生理作用

MMK-1 is a potent and selective FPR2 (FPRL-1) agonist (Ca²⁺ flux EC50 <2 nM/FPR2 vs. >10 μM/FPR1 with respective HEK293 transfectants) and an effective calcium-mobilizing and chemotactic agent for human monocytes & neutrophils (1-1000 nM). MMK-1 increases pertussis toxin-sensitive inflammatory cytokines production in human monocyte cultures (50 ng/mL PT & 10 μM MMK-1), exerts anxiolytic-like activities in mice (100 pmol/mouse icv) and shows anti-alopecia efficacy in rats in vivo (100 mg/kg p.o. or 10 mg/kg i.p.).

基本信息

经验(实验)分子式	C₇₅H₁₂₃N₁₉O₁₈S · xC₂HF₃O₂
分子量	1610.96 (free base basis)

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	film or powder
颜色	white to beige
储存温度	−20℃