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CAS: 26675-46-7
分子式: C3H2ClF5O
分子量: 184.49
沸点: 48.5℃
中文名称: 
异氟烷
活宁液
1-氯-2,2,2-三氟乙基二氟甲醚
异氟醚
英文名称: 
1-Chloro-2,2,2-trifluoroethyl drfluoromethyl ether
chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane
chloro-2,2,2-trifluoro difluoromethyl ether
(Difluoromethyl)-(1-chloro-2,2,2-trifluoroethyl)ether
ether, 1-chloro-2,2,2-trifluoroethyl difluoromethyl
(+-)-isoflurane
1-chloro-2,2,2-trifluoroethyl difluoromethyl ether
2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane
2-chloro-2-(difluoromethoxy)-1,1,1-trifluoro-ethan
forane
isoflurane
r-e 235dal
展开更多英文名
性质描述: 无色透明液体。沸点48.5℃,25℃蒸气压44.0kPa。相对密度1.45,折光率(nD20)1.3002。略带刺激性醚样臭。
生产方法: 将50g(0.23mol)1-氯-2,2,2-三氟乙基二氯甲醚和1.5g五氯化锑加入不锈钠反应器中,搅拌,冷却,通入氟化氢气体,保持温度在0℃,反应至逸出的氯化氢计0.35mol为止,和26g氟化产物,线度为90%,用分馏获得纯品。
用途: 该品为吸入麻醉药,与安氟醚是同分异构体。抑制呼吸作用弱于安氟醚,强于氟烷。对心肌抑制是同类药最轻的一种。适用于全身麻醉。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C2485TCI1-Chloro-2,2,2-trifluoroethyl Difluoromethyl Ether>98.0%(GC)450元/5G;   1430元/25G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C3H2ClF5O = 184.49
外观与形状(20℃)液体
Reaxys-RN1852087
PubChem物质ID125307939
Merck Index (14)5175
MDL编号MFCD00066609

技术规格

AppearanceColorless to Almost colorless clear liquid
Purity(GC)min. 98.0 %

物性(参考值)

沸点49 ℃
比重1.51
折射率1.30

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H371 : 可能损害器官。
H335 : 可能造成呼吸道刺激。
H336 : 可能造成昏昏欲睡或眩晕。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P260 : 不要吸入粉尘/ 烟/ 气体/ 烟雾/ 蒸气/ 喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P271 : 只能在室外或通风良好之处使用。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P308+P311 : 如接触到或有疑虑:呼叫急救中心/医生。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P304 + P340 + P312 : 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。如感觉不适,呼叫急救中心/医生。
P403 + P233 : 存放在通风良好的地方。保持容器密闭。
P405 : 存放处须加锁。

相关法规

RTECS#KN6799000
540340J&K1-Chloro-2,2,2-trifluoroethyl Difluoromethyl Ether98%375元/5G;   1330元/25G;   展开

基本信息

分子式C3H2ClF5O
分子量184.49
沸点48-49
密度1.496
MDL编码MFCD00066609
Beilstein1852087
Merck14,5175
EINECS 编号247-897-7

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
H336
防范说明P261
P280
P305+P351+P338
P304+P340
P405
P501a
RTECSKN6799000
TSCA
L17315Alfa Aesar1-Chloro-2,2,2-trifluoroethyl Difluoromethyl Ether97%1010元/5g;   3770元/25g;   展开

应用

1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether is a useful solvent for dispersing fluorinated materials.

For Research and Development use only. Not to be used in clinical studies

备注
Containers which are opened must be carefully resealed and kept upright to prevent leakage.

基本信息

MDL
MFCD00066609

EINECS
247-897-7

分子式
CF3CHClOCHF2

分子量
184.49

沸点
48-49°

密度
1.496

折射率
<1.3

灵敏度
Ambient temperatures.

溶解性
Soluble in chloroform and ethyl acetate. Not miscible or difficult to mix in water.

Beilstein
1852087

Merck
14,5175

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335-H336
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.May cause drowsiness or dizziness.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38-67
Irritating to eyes, respiratory system and skin.Vapours may cause drowsiness and dizziness.

安全等级
23-26-37-60
Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

RTECS
KN6799000

TSCA

PHR2874SupelcoIsofluranepharmaceutical secondary standard, certified reference material2338.18元/1.2 mL;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

生化/生理作用

Isoflurane is a tandem pore potassium channel activator. It is also a very widely used anesthetic for animal research and for in vitro studies on anesthesia mechanisms.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

基本信息

经验(实验)分子式C3H2ClF5O
分子量184.49

产品性质

等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 1.2 mL
application(s)pharmaceutical
药典可追溯性traceable to PhEur Y0000858
traceable to USP 1349003
储存温度2-30℃
InChI1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H
InChI keyPIWKPBJCKXDKJR-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H336
预防措施声明P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501
危险分类STOT SE 3
靶器官Central nervous system
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
792632Sigma-AldrichIsoflurane393.69元/250 MG;   1166.57元/1 G;   展开

产品说明

应用

异氟烷是一种挥发性麻醉剂,主要用于研究其与生物系统的相互作用。

包装

1 g in glass bottle
250 mg in glass bottle

基本信息

经验(实验)分子式C3H2ClF5O
分子量184.49
EC 号247-897-7
MDL编号MFCD00066609
PubChem化学物质编号329768352
NACRESNA.22

产品性质

质量水平100
蒸汽压238 mmHg ( 20 ℃)
形式liquid
折射率n20/D 1.302
bp48.5 ℃
密度1.510 g/mL at 25 ℃
储存温度2-8℃
SMILES stringFC(F)OC(Cl)C(F)(F)F
InChI1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H
InChI keyPIWKPBJCKXDKJR-UHFFFAOYSA-N
Gene Informationhuman ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879), GLRA1(2741), GLRB(2743), KCNK10(54207), KCNK18(338567), KCNK2(3776), KCNK3(3777), KCNK9(51305)

安全信息

象形图GHS07
警示用语:Warning
危险声明H336
预防措施声明P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501
危险分类STOT SE 3
靶器官Central nervous system
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1349003USPIsofluraneUnited States Pharmacopeia (USP) Reference Standard3231.47元/1 ML;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Isoflurane is a tandem pore potassium channel activator. It is also a very widely used anesthetic for animal research and for in vitro studies on anesthesia mechanisms.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C3H2ClF5O
分子量184.49
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
InChI1S/C3H2ClF5O/c4-1(3(7,8)9)10-2(5)6/h1-2H
InChI keyPIWKPBJCKXDKJR-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H336
预防措施声明P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501
危险分类STOT SE 3
靶器官Central nervous system
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
004529Fluorochem1-Chloro-2,2,2-trifluoroethyl Difluoromethyl Ether97%220元/1g;   440元/5g;   1518元/25g;   展开

基本信息

CAS Number26675-46-7
MDL NumberMFCD00066609
Boiling Point49℃
Density1.45

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H373: May cause damage to organs ..
H336: May cause drowsiness or dizziness
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P314: Get medical advice/attention if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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