CAS 26615-21-4; f)thiepin, 2-chloro-11-(2-(dimethylamino)ethoxy)-dibenzo(

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CAS:

26615-21-4

分子式:

C₁₈H₁₈ClNOS

分子量:

331.86

沸点:

478.4±45.0 °C

熔点:

90-91 °C

英文名称:

f)thiepin, 2-chloro-11-(2-(dimethylamino)ethoxy)-dibenzo(

2-((8-chlorodibenzo(b,f)thiepin-10-yl)oxy)-n,n-dimethylethanamine

2-chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin

2-chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin

2-chloro-11-(2-dimethylaminoethoxy)-dibenzo(b,f)thiepine

compound-4

lodopin

zotepina

zotepine

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

Z928860

MACKLIN

佐替平

98%

460元/50mg; 1371元/250mg; 3234元/1g;

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储存：室温

Z0877

Sigma-Aldrich

Zotepine

1027.89元/10 MG; 3261.46元/50 MG;

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产品说明

应用

Zotepine has been used as an anti-psychotic agent:

in biophysical studies with serotonin 2A receptor (5-HT_2AR)
to study its effects on the inhibition of human organic cation transporter 1 (hOCT1)
to study its protective effects on the human embryonic kidney (HEK cells)

包装

10, 50 mg in glass bottle

生化/生理作用

Zotepine acts as an antagonist of dopamine D1, D2, and serotonin (5-HT_2A/2C) receptors, and noradrenaline transporters. It shows therapeutic effects against schizophrenia and acute mania.
Zotepine is an atypical antipsychotic.

特点和优势

This compound was developed by Astellas. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. Z0877.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

基本信息

经验(实验)分子式	C₁₈H₁₈ClNOS
分子量	331.86
MDL编号	MFCD00868143
PubChem化学物质编号	329831602
NACRES	NA.77

产品性质

测定	>98% (HPLC)
质量水平	100
形式	powder
颜色	white to off-white
溶解性	DMSO: ≥20 mg/mL
创始人	Astellas
储存温度	room temp
SMILES string	CN(C)CCOC1=Cc2ccccc2Sc3ccc(Cl)cc13
InChI	1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3
InChI key	HDOZVRUNCMBHFH-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H400
预防措施声明	P273
危险分类	Acute Tox. 4 Oral - Aquatic Acute 1
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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