CAS 2645-32-1; thiocyanic acid c,c′-(2,6-diamino-3,5-pyridinediyl) ester; 2,6-diaminopyridine-3,5-bis(thiocyanate); pr-619

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CAS:

2645-32-1

分子式:

C₇H₅N₅S₂

分子量:

223.28

中文名称:

thiocyanic acid c,c′-(2,6-diamino-3,5-pyridinediyl) ester; 2,6-diaminopyridine-3,5-bis(thiocyanate)

硫氰酸 c,c′-(2,6-二氨基-3,5-吡啶二基)酯；2,6-二氨基吡啶-3,5-双(硫氰酸酯)

2,6-二氨基-3,5-二硫氰基吡啶

英文名称:

pr-619

2,6-diamino-3,5-dithiocyanopyridine

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

P833264

MACKLIN

2,6-二氨基-3,5-二硫氰基吡啶

98%

385元/10mg; 855元/50mg; 1831元/250mg; 3400元/1g;

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储存：-20°C
状态：白色到米黄色到浅黄色到黄色到黄绿色粉末

P797110

MACKLIN

2,6-二氨基-3,5-二硫氰基吡啶

10mM in DMSO

463元/1ml;

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储存：-20°C

SML0430

Sigma-Aldrich

PR-619

≥95% (HPLC)

1290.53元/1 MG; 2972.33元/5 MG;

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产品说明

应用

PR-619已被用于：

作为裂解缓冲液的成分，以及用作去泛素化酶抑制剂用于处理来源于SILAC-标记Jurkat 细胞的蛋白质
作为去泛素化酶抑制剂用于研究其对腺相关病毒 (AAV) 转导的影响
用于泛素化检测用放射免疫沉淀测定缓冲液 (RIPA)

包装

1, 5 mg in glass bottle

生化/生理作用

PR-619 是一种细胞可透过性广谱去泛素化酶(DBUs)抑制剂。PR-619 在不直接影响蛋白酶体活性的情况下，诱导细胞中多泛素化蛋白质的积聚。

基本信息

经验(实验)分子式	C₇H₅N₅S₂
分子量	223.28
MDL编号	MFCD00830384
PubChem化学物质编号	329825425
NACRES	NA.77

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 5 mg/mL (clear solution)
储存温度	−20℃
SMILES string	Nc1nc(N)c(SC#N)cc1SC#N
InChI	1S/C7H5N5S2/c8-2-13-4-1-5(14-3-9)7(11)12-6(4)10/h1H,(H4,10,11,12)
InChI key	ZXOBLNBVNROVLC-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3

462084

Fluorochem

3,5-Dithiocyanatopyridine-2,6-diamine

95%

2684元/250mg; 6424元/1g; 16610元/5g;

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基本信息

CAS Number	2645-32-1
MDL Number	MFCD00830384

安全信息

图形或危害标志
危险性说明	H302: Harmful if swallowed. H315: Causes skin irritation. H318: Causes serious eye damage. H335: May cause respiratory irritation. H317: May cause an allergic skin reaction
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: . P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310: Immediately call a POISON CENTER or doctor/physician. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see . on this label). P330: Rinse mouth. P332 + P313: If skin irritation occurs: Get medical advice/ attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to local regulations.

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