CAS 26172-54-3; 2-甲基-3(2H)-异噻唑酮盐酸盐; 3(2H)-Isothiazolone, 2-methyl-, hydrochloride

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CAS:

26172-54-3

分子式:

C4H5NOS·ClH

分子量:

151.61

中文名称:

2-甲基-3(2H)-异噻唑酮盐酸盐

英文名称:

3(2H)-Isothiazolone, 2-methyl-, hydrochloride

2-Methyl-4-isothiazolin-3-one hydrochloride

2-methyl-3(2h)-isothiazolon hydrochloride

2-methyl-4-isothiazolin-3-one*hydrochloride

3(2H)-Isothiazolone,2-methyl-,hydrochloride

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

M875228

MACKLIN

2-甲基-4-异噻唑啉-3-酮盐酸盐

98%

33元/1g; 50元/5g; 152元/25g; 526元/100g;

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储存：2-8°C
状态：白色到灰白色晶体或粉末

M6045

Sigma-Aldrich

2-Methyl-4-isothiazolin-3-one hydrochloride

≥99%

1572.96元/1 G; 6333.19元/5 G;

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产品说明

一般描述

2-甲基-4-异噻唑啉-3-酮盐酸盐(MIT，甲基异噻唑啉酮)是合成异噻唑啉酮的衍生物。

应用

Methylisothiazolinone (MIT) has been used:

as a cytotoxic substance to investigate its effect on bronchial epithelial cells (BEAS-2B cells) and its role in apoptotic cell death
to study the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites

生化/生理作用

2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a skin sensitizer known to cause contact dermatitis and allergy. It is extensively used in the cosmetic industry as a preservative. MIT is a neurotoxin and its prolonged exposure may lead to neuronal death and inhibition of neurite outgrowth.

基本信息

经验(实验)分子式	C₄H₅NOS · HCl
分子量	151.61
Beilstein	3993054
EC 号	247-499-3
MDL编号	MFCD06804636
PubChem化学物质编号	24897073

产品性质

质量水平	200
测定	≥99%
作用机制	protein synthesis \| interferes
储存温度	2-8℃
SMILES string	Cl[H].CN1SC=CC1=O
InChI	1S/C4H5NOS.ClH/c1-5-4(6)2-3-7-5;/h2-3H,1H3;1H
InChI key	SJXPQSRCFCPWQQ-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H314 - H317 - H410
预防措施声明	P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
危险分类	Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1A
补充剂危害	EUH071
储存分类代码	6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

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