CAS 254750-02-2; emricasan

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CAS:

254750-02-2

分子式:

C₂₆H₂₇F₄N₃O₇

分子量:

569.5

英文名称:

emricasan

用途:

Emricasan (PF 03491390; IDN-6556) 是不可逆的 pan-caspase 抑制剂。

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货号

品牌

产品名称

规格

包装、参考价格

详情

E879996

MACKLIN

Emricasan

≥99%

554元/5mg; 898元/10mg; 1732元/25mg; 2800元/50mg; 5200元/100mg;

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储存：2-8℃
状态：白色到灰白色固体

E797641

MACKLIN

Emricasan

10mM in DMSO

1349元/1ml;

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储存：-20°C

SML2227

Sigma-Aldrich

Emricasan

≥98% (HPLC)

1642.38元/5 MG; 6621.04元/25 MG;

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产品说明

生化/生理作用

Emricasan is an antiapoptotic pan-caspase inhibitor. It has been in clinical trials for the treatment of non-alcoholic steatohepatitis (NASH) with advanced fibrosis (scarring) and cirrhosis. Emricasan has also been shown to protect infected astrocytes from ZIKV-induced cell death.
Emricasan, formerly known as IDN-6556, in combination with birinapan is used to treat acute myeloid leukemia (AML). This small molecule irreversible inhibitor is under clinical investigation to reduce hepatic injury and liver fibrosis.

基本信息

经验(实验)分子式	C₂₆H₂₇F₄N₃O₇
分子量	569.50
MDL编号	MFCD11840420
NACRES	NA.77

产品性质

测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
运输	wet ice
储存温度	−20℃
SMILES string	CC(C)(C)C1=C(NC(C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(COC2=C(F)C(F)=CC(F)=C2F)=O)=O)=O)=O)C=CC=C1

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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