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CAS: 25332-39-2
分子式: C19H23Cl2N5O
分子量: 408.33
沸点: 528.5ºC
熔点: 223 °C
中文名称: 
曲唑酮
盐酸曲唑酮
英文名称: 
Trazodone HCl
2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-s-triazolo(4,3-a)pyridin- 3(2h
)-one hcl
af 1161
desyrel
kb-831
molipaxin
pragmazone
thombran
tombran
trazodone hydrochloride
trittico
展开更多英文名
用途: 抗忧郁药。
推荐供应商
货号品牌产品名称规格包装、参考价格
T859255MACKLIN盐酸曲唑酮98%409元/1g;   1220元/5g;   2144元/25g;   6179元/100g;   咨询
储存:2-8ºC
状态:白色到浅黄色粉末或晶体
T795654MACKLIN盐酸曲唑酮2mM in DMSO302元/1ml;   咨询
储存:-20°C
460455J&KTrazodone hydrochloride99%607元/1G;   咨询

基本信息

分子式C18H22N5O·HCl
分子量408.32
熔点222-227
MDL编码MFCD00079603
Merck14,9579
EINECS 编号246-855-5

安全信息

图形或危害标志
提示语Warning
危险说明H302
H351
防范说明P264
P281
P301+P312
P308+P313
P405
P501A
WGK3
RTECSXZ5660000
TSCA
T6154Sigma-AldrichTrazodone hydrochloride≥99% (HPLC), powder838.15元/1 G;   2069.62元/5 G;   咨询

产品说明

包装

1, 5 g in glass bottle

生化/生理作用

增强 5-羟色胺摄取阻断剂活性、并具有完全5-HT 2C 5 羟色胺受体激动剂活性的抗抑郁药。它代谢为 5-HT 1 5-羟色胺受体激动剂 1-(3-氯苯基)哌嗪。

特点和优势

该化合物出现在受体分类和信号转导手册的生物胺转运体页。想要浏览手册的其他页面,请点击此处。
该化合物由Bristol-Myers Squibb开发。要浏览其他药物开发化合物和批准的药物/候选药物列表,单击此处。

制备说明

盐酸曲唑酮溶于 25 mg/mL 甲醇中,得到澄清、无色溶液。在 50 mg/mL 的水中溶解,加热得到浑浊的无色溶液。此外,产品可溶于 DMSO 或 0.1 NHCl (7.4 mg/mL)。在45% (w/v) 2-羟丙基-β-环糊精水溶液中的溶解度为 23.3 mg/mL。然而,它几乎不溶于其他常见有机溶剂。对于 HPLC 检测,本品可以 0.25 mg/mL 溶于 50:50 水:甲醇 (v/v) 中,因为其获得的溶出度和峰形结果优于本品 1 mg/mL 水溶液。

基本信息

经验(实验)分子式C19H22ClN5O · HCl
分子量408.32
EC 号246-855-5
MDL编号MFCD00079603
PubChem化学物质编号24278136
NACRESNA.77

产品性质

质量水平200
测定≥99% (HPLC)
形式powder
溶解性45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble 23.3 mg/mL
methanol: soluble 25 mg/mL, clear, colorless
0.1 M HCl: soluble 7.4 mg/mL
DMSO: soluble
H2O: soluble, hazy, colorless
创始人Bristol-Myers Squibb
SMILES stringCl[H].Clc1cccc(c1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2
InChI1S/C19H22ClN5O.ClH/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25;/h1-3,5-7,9,15H,4,8,10-14H2;1H
InChI keyOHHDIOKRWWOXMT-UHFFFAOYSA-N
Gene Informationhuman ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2C(3358), SLC6A4(6532)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H351
预防措施声明P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
危险分类Acute Tox. 4 Oral - Carc. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备Eyeshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
PHR3372SupelcoTrazodone hydrochloridecertified reference material, pharmaceutical secondary standard2644.15元/500 mg;   咨询

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

基本信息

经验(实验)分子式C19H22ClN5O · HCl
分子量408.32
MDL编号MFCD00079603

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
包装pkg of 500 mg
药典可追溯性traceable to USP 1673500
储存温度2-30℃
SMILES stringCl[H].Clc1cccc(c1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2
InChI1S/C19H22ClN5O.ClH/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25;/h1-3,5-7,9,15H,4,8,10-14H2;1H
InChI keyOHHDIOKRWWOXMT-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H351
预防措施声明P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
危险分类Acute Tox. 4 Oral - Carc. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP590Trazodone hydrochlorideBritish Pharmacopoeia (BP) Reference Standard2768.35元/100 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C19H22ClN5O · HCl
分子量408.32
MDL编号MFCD00079603
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
格式neat
储存温度2-8℃
SMILES stringCl[H].Clc1cccc(c1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2
InChI1S/C19H22ClN5O.ClH/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25;/h1-3,5-7,9,15H,4,8,10-14H2;1H
InChI keyOHHDIOKRWWOXMT-UHFFFAOYSA-N
Gene Informationhuman ... HTR2A(3356), HTR2C(3358), SLC6A4(6532)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H351
预防措施声明P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313
危险分类Acute Tox. 4 Oral - Carc. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1673500USPTrazodone hydrochlorideUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C19H22ClN5O · HCl
分子量408.32
MDL编号MFCD00079603
PubChem化学物质编号329751367

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCl[H].Clc1cccc(c1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2
InChI1S/C19H22ClN5O.ClH/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25;/h1-3,5-7,9,15H,4,8,10-14H2;1H
InChI keyOHHDIOKRWWOXMT-UHFFFAOYSA-N
Gene Informationhuman ... HTR2A(3356), HTR2C(3358), SLC6A4(6532)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H351
预防措施声明P280 - P301 + P312 + P330
危险分类Acute Tox. 4 Oral - Carc. 2
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP591Trazodone hydrochloride impurity standardBritish Pharmacopoeia (BP) Reference Standard1989元/50 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C19H22ClN5O · HCl
分子量408.32
MDL编号MFCD00079603

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
格式mixture
储存温度2-8℃
SMILES stringCl[H].Clc1cccc(c1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2
InChI1S/C19H22ClN5O.ClH/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25;/h1-3,5-7,9,15H,4,8,10-14H2;1H
InChI keyOHHDIOKRWWOXMT-UHFFFAOYSA-N
Gene Informationhuman ... HTR2A(3356), HTR2C(3358), SLC6A4(6532)

安全信息

象形图GHS07GHS08
警示用语:Warning
危险声明H302 - H351
预防措施声明P201 - P202 - P264 - P280 - P301 + P312 + P330 - P308 + P313
危险分类Acute Tox. 4 Oral - Carc. 2
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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