| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 |
| S794795 | MACKLIN | 远志皂苷元 | 10mM in DMSO | 720元/1ml; | 展开 |
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| S861354 | MACKLIN | 远志皂苷元 | ≥98%(HPLC) | 708元/20mg; | 展开 |
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| 257831 | J&K | Senegenin | 98%, 一种具有抗氧化和抗炎活性的天然产物 | 989元/1MG; | 展开 |
基本信息 | 分子式 | C30H45ClO6 | | 分子量 | 537.13 | | MDL编码 | MFCD00466906 | | 存储条件 | Freezer -20℃ |
产品描述 Senegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and antiinflammatory activity. 靶点（IC50 & Targe） Caspase-3 安全信息 | 图形或危害标志 |   | | 危险说明 | H302
H400 | | 防范说明 | P273 | | UN号码 | 3077 | | 危险分类 | 9 | | 包装等级 | III |
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| SML1001 | Sigma-Aldrich | Senegenin | ≥98% (HPLC) | 1396.09元/5 MG; | 展开 |
产品说明 生化/生理作用 Senegenin is lipophilic and hydrosoluble. It is chemically represented as (2β,3β,4α,12α)-12-(Chloromethyl)-2,3-dihydroxy-27-norolean-13-ene-23,28-dioic acid. Senegenin plays a protective role against memory impairment in a dose and time dependent manner.
Senegenin (Tenuigenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and antiinflammatory activity. Senegenin has been studied for nootropic ability to improve cognition. In several independent studies, Tenuigenin attenuated α-synuclein-induced cytotoxicity and α-synuclein phosphorylation by down-regulating polo-like kinase 3 (PLK3) in α-synuclein cell model of Parkinson′s Disease, improved behavioral Y-maze learning by enhancing synaptic plasticity in mice, and attenuated hepatic ischemia-reperfusion induced cognitive dysfunction by increasing hippocampal N-methyl-D-aspartate (NMDA) receptor NR2B subunit expression in rats. 基本信息 | 经验(实验)分子式 | C30H45ClO6 | | 分子量 | 537.13 | | MDL编号 | MFCD00466906 | | PubChem化学物质编号 | 329825628 | | NACRES | NA.77 |
产品性质 | 质量水平 | 100 | | 测定 | ≥98% (HPLC) | | 形式 | powder | | 颜色 | white to beige | | 溶解性 | DMSO: 10 mg/mL, clear | | 储存温度 | 2-8℃ | | SMILES string | [H][C@]12[C@](CCC3=C2[C@@H](CCl)C[C@@]4([H])[C@@]3(C)CC[C@]5([H])[C@]4(C)C[C@H](O)[C@H](O)[C@]5(C(O)=O)C)(C(O)=O)CCC(C)(C)C1 | | InChI | 1S/C30H45ClO6/c1-26(2)10-11-30(25(36)37)9-6-17-22(18(30)13-26)16(15-31)12-21-27(17,3)8-7-20-28(21,4)14-19(32)23(33)29(20,5)24(34)35/h16,18-21,23,32-33H,6-15H2,1-5H3,(H,34,35)(H,36,37)/t16-,18+,19+,20-,21+,23+,27+,28+,29+,30-/m1/s1 | | InChI key | CWHJIJJSDGEHNS-MYLFLSLOSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 | | 预防措施声明 | P301 + P312 + P330 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| PHL82650 | | Senegenin | phyproof® Reference Substance | 5303.89元/10 MG; | 展开 |
产品说明 一般描述 This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG 生化/生理作用 Senegenin (Tenuigenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and antiinflammatory activity. Senegenin has been studied for nootropic ability to improve cognition. In several independent studies, Tenuigenin attenuated α-synuclein-induced cytotoxicity and α-synuclein phosphorylation by down-regulating polo-like kinase 3 (PLK3) in α-synuclein cell model of Parkinson′s Disease, improved behavioral Y-maze learning by enhancing synaptic plasticity in mice, and attenuated hepatic ischemia-reperfusion induced cognitive dysfunction by increasing hippocampal N-methyl-D-aspartate (NMDA) receptor NR2B subunit expression in rats. 法律信息 phyproof is a registered trademark of PhytoLab GmbH & Co. KG 基本信息 | 经验(实验)分子式 | C30H45ClO6 | | 分子量 | 537.13 | | MDL编号 | MFCD00466906 |
产品性质 | 等级 | primary reference standard | | 产品线 | phyproof® Reference Substance | | 测定 | ≥95.0% (HPLC) | | manufacturer/tradename | PhytoLab | | 格式 | neat | | SMILES string | [H][C@]12[C@](CCC3=C2[C@@H](CCl)C[C@@]4([H])[C@@]3(C)CC[C@]5([H])[C@]4(C)C[C@H](O)[C@H](O)[C@]5(C(O)=O)C)(C(O)=O)CCC(C)(C)C1 | | InChI | 1S/C30H45ClO6/c1-26(2)10-11-30(25(36)37)9-6-17-22(18(30)13-26)16(15-31)12-21-27(17,3)8-7-20-28(21,4)14-19(32)23(33)29(20,5)24(34)35/h16,18-21,23,32-33H,6-15H2,1-5H3,(H,34,35)(H,36,37)/t16-,18+,19+,20-,21+,23+,27+,28+,29+,30-/m1/s1 | | InChI key | CWHJIJJSDGEHNS-MYLFLSLOSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 | | 预防措施声明 | P301 + P312 + P330 | | 危险分类 | Acute Tox. 4 Oral | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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