CAS 2448-68-2; 4'-bipiperidine)-4'-carboxamide, 1'-(3-(p-fluorobenzoyl)propyl)-( dihydrochl

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CAS:

2448-68-2

分子式:

C₂₁H₃₂Cl₂FN₃O₂

分子量:

448.40

熔点:

203-218 °C

英文名称:

4'-bipiperidine)-4'-carboxamide, 1'-(3-(p-fluorobenzoyl)propyl)-( dihydrochl

pipamperone dichlorhydrate

pipamperone dihydrochloride

pipamperone hydrochloride

propitan

4'-bipiperidine)-4'-carboxamide,1'-(3-(p-fluorobenzoyl)propyl)-( dihydrochloride

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

F939983

MACKLIN

1-[4-(4-氟苯基)-4-氧亚基丁基]-[1,4-联哌啶]-4-甲酰胺二盐酸

95%

1560元/100mg; 2340元/250mg; 4680元/1g;

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储存：2-8°C
状态：白色固体

P3246

Sigma-Aldrich

Pipamperone dihydrochloride

~99% (HPLC), powder

2521.28元/100 MG;

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产品说明

应用

Pipamperone dihydrochloride may be used:

as an internal standard in liquid chromatography with coulometric detection
as an antipsychotic drugs to test its interaction with human ether-a-go-go-related gene (hERG) channel
as an internal standard to spike human colostrum samples for reversed phase liquid chromatography- ultraviolet (LC-UV) analysis

包装

100 mg in poly bottle

生化/生理作用

Pipamperone, a butyrophenone derivative is a pharmacological chaperone and is a membrane-permeable dopamine receptor D4 (DRD4) antagonist. The affinity of pipamperone is higher for DRD4 and 5-hydroxytryptamine 2A receptor (5-HT2A) in comparison with DRD2. It may be useful therapeutic in treating behavioral disorders and psychomotor agitation symptoms.
D₂ dopamine receptor antagonist; 5-HT₂ serotonin receptor antagonist; antipsychotic.

特点和优势

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

基本信息

经验(实验)分子式	C₂₁H₃₀N₃O₂F · 2HCl
分子量	448.40
EC 号	219-507-5
MDL编号	MFCD00242980
PubChem化学物质编号	24724576
NACRES	NA.77

产品性质

质量水平	100
测定	~99% (HPLC)
形式	powder
颜色	white
溶解性	H₂O: >2.0 mg/mL
创始人	Johnson & Johnson
SMILES string	Cl[H].Cl[H].NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N3CCCCC3
InChI	1S/C21H30FN3O2.2ClH/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25;;/h6-9H,1-5,10-16H2,(H2,23,27);2*1H
InChI key	BMXXSXQVMCXGJM-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 1
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves

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