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CAS: 2447-57-6
分子式: C12H14O2N4S
分子量: 310.33
熔点: 190-194°C
中文名称: 
磺胺邻二甲氧嘧啶
周效磺胺
磺胺-5,6-二甲氧嘧啶
英文名称: 
Sulfadimoxine
4-amino-n-(5,6-dimethoxy-4-pyrimidinyl)-benzenesulfonamid
4-amino-n-(5,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
4-sulfanilamido-5,6-dimethoxypyrimidine
6-(4-aminobenzenesulfonamido)-4,5-dimethoxypyrimidine
fanasil
fanzil
n'-(5,6-dimethoxy-4-pyrimidyl)sulfanilamide
ro 4-4393
sulfadoxine
sulforthomidine
sulphadoxine
sulphormethoxine
wr 4873
Sulfadoxin
展开更多英文名
用途: 超长效类磺胺药物，用于治疗脑膜炎、尿路感染等。
推荐供应商
货号品牌产品名称规格包装、参考价格
S818335MACKLIN磺胺多辛96%54元/2g;   126元/10g;   450元/50g;   888元/100g;   咨询
储存：2~8°C,干燥
状态：白色到浅黄色粉末
S0899TCISulfadoxin>98.0%(T)(HPLC)305元/5G;   705元/25G;   咨询

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C12H14N4O4S = 310.33
外观与形状(20℃)固体
Reaxys-RN625453
PubChem物质ID172089109
Merck Index (14)8906
MDL编号MFCD00792890

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %
Melting point196.0 to 200.0 ℃

物性(参考值)

熔点198 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。

相关法规

RTECS#DA9500000
192604J&KSulfadoxine98%466元/5G;   1606元/25G;   咨询

基本信息

分子式C12H14N4O4S
分子量310.33
熔点190-194
MDL编码MFCD00792890
Beilstein625453
Merck14,8906
EINECS 编号219-504-9
存储条件Store at 2-8℃

一般描述

Chemical structure: sulfonamide

应用

Sulfadoxine is a sulfonamide antibiotic used in combination with pyrimethamine for the treatment or prevention of malaria. It is also used to treat various infections in livestock. Sulfadoxine and pyrimethamine is indicated for the treatment of Plasmodium falciparum malaria in patients where chloroquine resistance is suspected. It is used to study infections caused by Toxoplasma gondii and has been used to prevent infections after surgery during animal studies.

生化/生理作用

Sulfadoxine is a sulfonamide antibacterial that inhibits dihydropteroate synthase (DHPS), an enzyme that transforms 4-aminobenzoic acid (PABA) in the synthesis of dihydropteroic acid. This enzyme is also a component of the folate metabolic pathway and is upstream of dihydrofolate reductase (DHFR).

其他说明

Keep container tightly closed in a dry and well-ventilated place.Storage class (TRGS 510): Non Combustible Solids

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK2
RTECSDA9500000
R10835Alfa AesarSulfadoxine Standard solution100ppm168元/1ml;   咨询

安全信息

危险等级
3

R11922Alfa AesarSulfadoxine,1000ppm352元/1ml;   咨询

安全信息

危险等级
3

S1950000SulfadoxineEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C12H14N4O4S
分子量310.33
Beilstein625453
MDL编号MFCD00792890
PubChem化学物质编号329824497
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCOc1ncnc(NS(=O)(=O)c2ccc(N)cc2)c1OC
InChI1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI keyPJSFRIWCGOHTNF-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语：Warning
危险声明H317 - H411
预防措施声明P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
危险分类Aquatic Chronic 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 2
BP310SulfadoxinBritish Pharmacopoeia (BP) Reference Standard2427元/100 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C12H14N4O4S
分子量310.33
Beilstein625453
EC 号219-504-9
MDL编号MFCD00792890
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
格式neat
储存温度2-8℃
SMILES stringCOc1ncnc(NS(=O)(=O)c2ccc(N)cc2)c1OC
InChI1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI keyPJSFRIWCGOHTNF-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语：Warning
危险声明H317 - H411
预防措施声明P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
危险分类Aquatic Chronic 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
31736SupelcoSulfadoxinVETRANAL®, analytical standard641.79元/250 MG;   咨询

产品说明

一般描述

Sulfadoxin belongs to the long acting group of sulfonamides, which acts by inhibiting dihydropteroate synthase in intracellular sporozoa such as Eimeria and Toxoplasma and Plasmodium.
Chemical structure: sulfonamide

应用

Sulfadoxin may be used as a reference standard for the determination of the analyte in plasma samples using packed-column supercritical fluid chromatography (SFC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

经验(实验)分子式C12H14N4O4S
分子量310.33
Beilstein625453
EC 号219-504-9
MDL编号MFCD00792890
PubChem化学物质编号329753909
NACRESNA.24

产品性质

等级analytical standard
质量水平100
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)clinical testing
格式neat
储存温度2-8℃
SMILES stringCOc1ncnc(NS(=O)(=O)c2ccc(N)cc2)c1OC
InChI1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI keyPJSFRIWCGOHTNF-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语：Warning
危险声明H317 - H411
预防措施声明P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
危险分类Aquatic Chronic 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 2
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
1626500USPSulfadoxineUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C12H14N4O4S
分子量310.33
Beilstein625453
MDL编号MFCD00792890
PubChem化学物质编号329751171
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCOc1ncnc(NS(=O)(=O)c2ccc(N)cc2)c1OC
InChI1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI keyPJSFRIWCGOHTNF-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语：Warning
危险声明H317 - H411
预防措施声明P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
危险分类Aquatic Chronic 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 2
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