CAS 2441-41-0; n-palmitoylglycine

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N912317

MACKLIN

N-Palmitoyl Glycine

98%

53元/250mg; 145元/1g; 721元/5g; 3542元/25g;

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储存：-20°C，密闭，干燥
状态：白色到灰白色粉末或固体

P0064

Sigma-Aldrich

PalGly

≥98% (HPLC), solid

2151.18元/10 MG;

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产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated.

特点和优势

This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₁₈H₃₅NO₃
分子量	313.48
MDL编号	MFCD00153471
PubChem化学物质编号	329820003
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
颜色	white to off-white
溶解性	DMSO: >10 mg/mL
储存温度	2-8℃
SMILES string	O=C(CCCCCCCCCCCCCCC)NCC(O)=O
InChI	1S/C18H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(20)19-16-18(21)22/h2-16H2,1H3,(H,19,20)(H,21,22)
InChI key	KVTFEOAKFFQCCX-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

870817P

Avanti

N-palmitoylglycine

Avanti Polar Lipids

555.56元/10 MG;

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产品说明

一般描述

N-palmitoylglycine belongs to the family of acyl amides, which are endogenous lipids with a potential to modulate pain and inflammation. Structurally, N-palmitoylglycine (PalGly) comprises 16-carbon saturated fatty acid attached to glycine through amide linkage. It is a structural analog of phospholipid-derived N-acyl ethanolamine. N-palmitoylglycine, a saturated lipid is endogenously produced at high levels in rat skin and spinal cord.

应用

N-palmitoylglycine has been used as an intact polar lipid (IPL) standard for determination of δ 15N values of nitrogen containing headgroups of IPLs using gas chromatography/combustion/isotope-ratio mass spectrometry.

生化/生理作用

N-palmitoylglycine stimulates calcium influx and nitric oxide (NO) production through calcium-sensitive nitric-oxide synthase in sensory neurons. It acts as a lipid activator of G-protein-coupled receptor GPR132.

包装

5 mL Amber Glass Screw Cap Vial (870817P-10mg)

基本信息

经验(实验)分子式	C₁₈H₃₅NO₃
分子量	313.48
NACRES	NA.25

产品性质

形式	powder
包装	pkg of 1 × 10 mg (870817P-10mg)
manufacturer/tradename	Avanti Polar Lipids 870817P
运输	dry ice
储存温度	−20℃
SMILES string	O=C(CCCCCCCCCCCCCCC)NCC(O)=O
InChI	1S/C18H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(20)19-16-18(21)22/h2-16H2,1H3,(H,19,20)(H,21,22)
InChI key	KVTFEOAKFFQCCX-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

493041

Fluorochem

Palmitoyl-glycine

= 99% (TLC)

968元/1g; 4180元/5g; 14608元/25g;

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基本信息

CAS Number	2441-41-0
MDL Number	MFCD00153471

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .