| CAS: | 24150-24-1 | ||||||||||
| 分子式: | C22H30O4 | ||||||||||
| 分子量: | 358.5 | ||||||||||
| 英文名称: |
| ||||||||||
| 用途: | tetramethyl Nordihydroguaiaretic acid (TMNDGA) is a synthetic derivative of NDGA, a non-selective lipoxygenase inhibitor. |
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||||||||||||||||||
| N912302 | MACKLIN | tetramethyl Nordihydroguaiaretic Acid | 98% | 767元/10mg; 2947元/50mg; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||||
储存：-20°C，密闭，干燥 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| T3455 | Sigma-Aldrich | Terameprocol | ≥98% (HPLC) | 870.88元/10 MG; 3319.3元/50 MG; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||||
产品说明 包装 10, 50 mg in glass bottle 生化/生理作用 Terameprocol is a synthetic derivative of NDGA, a non-selective lipoxygenase inhibitor. It inhibits Sp1 transcription factor binding at the HIV long terminal repeat promoter and at the α-ICP4 promoter, a gene essential for HSV replication, with IC50 values of 11 and 43.5 μM respectively. TMNDGA induces growth arrest and apoptosis by suppressing Sp1-dependent Cdc2 and survivin gene expression giving rise to its antitumorigenic activity. The in vivo growth of xenografts in numerous human tumor types was suppressed upon treatment with TMNDGA It also inhibits the growth of murine and human melanomas and human colon cancer in vivo without causing other tissue toxicity. 制备说明 Terameprocol is soluble in DMSO at a concentration that is greater than or equal to 10 mg/ml. 基本信息
产品性质
安全信息
| |||||||||||||||||||||||||||||||||||||||||||||||||||||
m.cnreagent.com
