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CAS: 23828-92-4
分子式: C13H19Br2ClN2O
分子量: 414.57
熔点: 235°C (分解)
中文名称: 
盐酸氨溴素
英文名称: 
5-dibromobenzyl)amino)- 4-(n-(2-amino- hydrochloride (e)-cyclohexano
4-(((2-amino-3,5-dibromophenyl)methyl)amino)-cyclohexano monohydrochlorid
4-((2-amino-3,5-dibromobenzyl)amino)-, hydrochloride, trans-cyclohexano
mucolear
mucosolvan
na 872 hydrochloride
trans-4-((2-amino-3,5-dibromobenzyl)amino)cyclohexanol hydrochloride
5-dibromobenzyl)amino)- 4-(n-(2-amino-hydrochloride (e)-cyclohexano
用途: 镇咳祛痰药,用于急、慢性呼吸道疾病,特别是慢性支气管炎的祛痰治疗。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
A797764MACKLIN盐酸氨溴索10mM in DMSO106元/1ml;   展开
储存:-20°C
状态:白色至灰白色固体
A833003MACKLIN盐酸氨溴索99%31元/1g;   90元/5g;   368元/25g;   708元/100g;   展开
储存:室温,干燥,密封
状态:白色到灰白色固体
A2360TCIAmbroxol Hydrochloride>98.0%(HPLC)(N)595元/5G;   1950元/25G;   展开

基本信息

纯度/分析方法>98.0%(HPLC)(N)
分子式/分子量C13H18Br2N2O・HCl = 414.57
外观与形状(20℃)固体
相关CAS RN18683-91-5
Reaxys-RN4894348
PubChem物质ID125307720
SDBS (AIST Spectral DB)52868
Merck Index (14)386
MDL编号MFCD00078932

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(with Total Nitrogen)min. 98.0 %

物性(参考值)

熔点235 ℃(dec.)
水溶性可溶
溶解性(可溶于)
溶解性(不溶于)乙醚

安全信息

信号词警告
危险性说明H303 : 吞咽可能有害。
防范说明P312 : 如感觉不适,呼叫急救中心/医生。

相关法规

RTECS#GV8425000
364981J&KAmbroxol HCl98%450元/100MG;   展开

基本信息

分子式C13H18Br2N2O.HCl
分子量414.57
MDL编码MFCD00078932
Y10585Alfa AesarAmbroxol (hydrochloride)594元/5g;   1087元/10g;   2024元/25g;   展开

基本信息

分子量
414.56

A0363700Ambroxol HydrochlorideEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   展开

产品说明

一般描述

本产品由现行药典发布和说明。随附的本产品的所有支持信息,包括SDS和任何产品信息彩页,均遵照现行药典许可而编制和发布。有关更多信息和支持,请参见现行药典网站。

包装

单位数量:125 mg。随时可能改变。产品按照发行药典的规定交付。有关当前单位数量,请访问 EDQM 对照品目录。

注意

请参见 由EDQM提供的SDS。。

其他说明

可能适用相应的销售限制。

基本信息

经验(实验)分子式C13H18Br2N2O · HCl
分子量414.56
MDL编号MFCD00078932
PubChem化学物质编号329770608
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCl.Nc1c(Br)cc(Br)cc1CN[C@@H]2CC[C@@H](O)CC2
InChI1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H/t10-,11-;
InChI keyQNVKOSLOVOTXKF-PFWPSKEQSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
A9797SupelcoAmbroxol Hydrochlorideanalytical standard1538.43元/5 G;   展开

产品说明

一般描述

盐酸氨溴索为粘液溶解祛痰药,是溴己新的代谢产物。 用于治疗以黏稠或黏液过多时为特征的呼吸障碍。

应用

有关合适仪器技术的更多信息,请参考产品的分析证书。如需进一步支持,请联系技术服务部门。
在使用反相顺序注射色谱法 (RP-SIC) 和反相高效液相色谱法 (RP-HPLC) 测定药物制剂中盐酸氨溴索含量时,盐酸氨溴索标准品可用作参比标准品。

生化/生理作用

溴己新代谢物。
钠通道 Nav1.8 阻断剂

基本信息

经验(实验)分子式C13H18Br2N2O · HCl
分子量414.56
EC 号245-899-2
MDL编号MFCD00078932
PubChem化学物质编号329771060
NACRESNA.24

产品性质

等级analytical standard
质量水平100
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)forensics and toxicology
pharmaceutical (small molecule)
veterinary
格式neat
储存温度2-8℃
SMILES stringCl.Nc1c(Br)cc(Br)cc1CN[C@@H]2CC[C@@H](O)CC2
InChI1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H/t10-,11-;
InChI keyQNVKOSLOVOTXKF-PFWPSKEQSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
PHR2063SupelcoAmbroxol HydrochloridePharmaceutical Secondary Standard; Certified Reference Material1425.44元/300 MG;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ambroxol hydrochloride is a mucolytic expectorant. It is a metabolite of bromhexine. It stimulates the transportation of viscous secretions in the respiratory organs and reduces the accumulation of the secretions.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Ambroxol Hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical dosage forms by high performance liquid chromatography and sequential injection chromatography.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAB8553 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C13H18Br2N2O · HCl
分子量414.56
MDL编号MFCD00078932

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
格式neat
药典可追溯性traceable to PhEur A0363700
储存温度2-8℃
SMILES stringCl.Nc1c(Br)cc(Br)cc1CN[C@@H]2CC[C@@H](O)CC2
InChI1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H/t10-,11-;
InChI keyQNVKOSLOVOTXKF-PFWPSKEQSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
053561FluorochemAmbroxol Hydrochloride0.97264元/1g;   1166元/25g;   展开

基本信息

CAS Number23828-92-4
MDL NumberMFCD00078932

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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