[登录] [免费注册]
试剂仪器网
位置:首页 > 资料中心 > 化工字典 > 2380-94-1
关键词:       仅模糊查询
CAS: 2380-94-1
分子式: C8H7NO
分子量: 133.15
熔点: 97-100℃
中文名称: 
4-羟基吲哚
英文名称: 
1H-Indol-4-ol
4-hydroxyindole
4-Indolol
性质描述: 该品为结晶体。熔点97-99℃。
生产方法: 以间苯二酚为原料,经异构化、催化氢化,再用溴代丙酮酸乙酯环合制得4-氧代四氢古马龙羧酸。将其加入经氨饱和的甲醇溶液中,在高压釜加热反应,生成4-氧代四氢吲哚。最后经脱氢、异构化制得4-羟基吲哚。
用途: 有机合成中用作中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格
H810933MACKLIN4-羟基吲哚98%46元/1g;   226元/5g;   1127元/25g;   咨询
储存:2~8°C
状态:白色到灰色晶体或固体
H0582TCI4-Hydroxyindole>99.0%(GC)590元/5G;   1690元/25G;   咨询

基本信息

纯度/分析方法>99.0%(GC)
分子式/分子量C8H7NO = 133.15
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况空气
Reaxys-RN114905
PubChem物质ID87570967
MDL编号MFCD00005667

技术规格

AppearanceWhite to Amber to Dark green powder to crystal
Purity(GC)min. 99.0 %
Melting point97.0 to 100.0 ℃

物性(参考值)

熔点99 ℃
水溶性实际上不溶
溶解性(可溶于)甲醇

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
100997J&K4-Hydroxyindole98%377元/250MG;   1243元/1G;   咨询

基本信息

分子式C8H7NO
分子量133.15
熔点97-99
MDL编码MFCD00005667
Beilstein114905
EINECS 编号219-177-2

安全信息

图形或危害标志
提示语Warning
危险说明H316
H320
H335
防范说明P281
P305+P351+P338
WGK3
TSCA
L14352Alfa Aesar4-Hydroxyindole98%780元/100mg;   3327元/500mg;   咨询

基本信息

MDL
MFCD00005667

EINECS
219-177-2

分子式
C8H7NO

分子量
133.15

熔点
97-99°

形态
Solid

Beilstein
114905

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

TSCA

219878Sigma-Aldrich4-Hydroxyindole99%551.07元/1 G;   咨询

产品说明

一般描述

人尿苷 5′ 与 4-羟基吲哚的葡糖基化反应-二磷酸葡萄糖醛酸转移酶已被发现 。

应用

  • 制备 N-β 的反应物-D-木糖基吲哚衍生物作为 SGLT2 抑制剂治疗糖尿病高血糖症
  • 用于制备靶向 HIV-1 整合酶与 LEDGF/p75 辅因子相互作用的小分子的反应物
  • 制备多巴胺 D2 受体拮抗剂的反应物
  • 制备 SCD 抑制剂 MF-438 的反应物
  • 用于制备碳-11 标记的 4-芳基-4H-色烯类癌症细胞凋亡成像新 PET 试剂的反应物
  • 用于制备 HCV 抑制剂吲哚/喹啉碳硫基酰胺衍生物的反应物

包装

1 g in glass bottle

基本信息

经验(实验)分子式C8H7NO
分子量133.15
Beilstein114905
EC 号219-177-2
MDL编号MFCD00005667
PubChem化学物质编号24853151
NACRESNA.22

产品性质

质量水平200
测定99%
mp97-99 ℃ (lit.)
SMILES stringOc1cccc2[nH]ccc12
InChI1S/C8H7NO/c10-8-3-1-2-7-6(8)4-5-9-7/h1-5,9-10H
InChI keyNLMQHXUGJIAKTH-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
1327157USP4-HydroxyindoleUnited States Pharmacopeia (USP) Reference Standard9901.74元/25 MG;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

  • 制备 N-β 的反应物-D-木糖基吲哚衍生物作为 SGLT2 抑制剂治疗糖尿病高血糖症
  • 用于制备靶向 HIV-1 整合酶与 LEDGF/p75 辅因子相互作用的小分子的反应物
  • 制备多巴胺 D2 受体拮抗剂的反应物
  • 制备 SCD 抑制剂 MF-438 的反应物
  • 用于制备碳-11 标记的 4-芳基-4H-色烯类癌症细胞凋亡成像新 PET 试剂的反应物
  • 用于制备 HCV 抑制剂吲哚/喹啉碳硫基酰胺衍生物的反应物

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

USP issued SDS can be found here.
Sales restrictions may apply

基本信息

经验(实验)分子式C8H7NO
分子量133.15
Beilstein114905
MDL编号MFCD00005667

产品性质

manufacturer/tradenameUSP
mp97-99 ℃ (lit.)
application(s)pharmaceutical
格式neat
储存温度2-8℃
SMILES stringOc1cccc2[nH]ccc12
InChI1S/C8H7NO/c10-8-3-1-2-7-6(8)4-5-9-7/h1-5,9-10H
InChI keyNLMQHXUGJIAKTH-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
016235Fluorochem4-Hydroxyindole98%220元/1g;   880元/5g;   2640元/25g;   咨询

基本信息

CAS Number2380-94-1
MDL NumberMFCD00005667
Melting Point95-100℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
CAS号首数字顺序排列: 1 2 3 4 5 6 7 8 9