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CAS: 2378619-75-9
分子式: C16H14N4S
分子量: 294.380
熔点: 142 °C
中文名称: 
3-[(联苯-4-基甲基)硫代]-6-甲基-1,2,4,5-四嗪
3-[[[1,1'-联苯]-4-基甲基]硫代]-6-甲基-1,2,4,5-四嗪
英文名称: 
b-tz
3-[(biphenyl-4-ylmethyl)thio]-6-methyl-1,2,4,5-tetrazine
3-[[[1,1'-biphenyl]-4-ylmethyl]thio]-6-methyl-1,2,4,5-tetrazine
推荐供应商
货号品牌产品名称规格包装、参考价格
B964785MACKLIN3-[(联苯-4-基甲基)硫代]-6-甲基-1,2,4,5-四嗪98%(HPLC)550元/250mg;   1776元/1g;   咨询
储存:室温, 惰性气体
状态:固体
B6273TCIb-Tz>98.0%(HPLC)590元/250MG;   1590元/1G;   咨询

基本信息

纯度/分析方法>98.0%(HPLC)
分子式/分子量C16H14N4S = 294.38
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况空气
Reaxys-RN35411097

技术规格

AppearanceLight red to Red powder to crystal
Purity(HPLC)min. 98.0 area%
Melting point140.0 to 144.0 ℃

物性(参考值)

熔点142 ℃
919950Sigma-Aldrich3-(([1,1′-Biphenyl]-4-ylmethyl)thio)-6-methyl-1,2,4,5-tetrazine>98%1094.54元/100 MG;   3253.43元/500 MG;   咨询

产品说明

应用

3-(([1,1′-Biphenyl]-4-ylmethyl)thio)-6-methyl-1,2,4,5-tetrazine (b-Tz) is a minimal tetrazine derivative capable of undergoing [4+2] Diels-Alder cycloaddition reactions with strained alkenes, which makes it highly useful in bioorthogonal labeling and cell detection applications. Tetrazines are often incorporated into chemical probes or other small-molecule tools using linkers that may impact physicochemical properties or the performance of the resulting conjugate product. Here, Lambert et al demonstrated the linker-free incorporation of b-Tz via silver-mediated Liebeskind-Srogl cross-coupling with a variety of aryl and heteroaryl boronic acids. This ″minimal″ tetrazine approach will facilitate the introduction of tetrazine into diverse complex molecules and improved probes for live-cell imaging and in vivo chemistry.

Supporting products
PdCl2(dppf): 697230
Ag2O: 226831

其他说明

Installation of Minimal Tetrazines through Silver-Mediated Liebeskind-Srogl Coupling with Arylboronic Acids

基本信息

经验(实验)分子式C16H14N4S
分子量294.37

产品性质

质量水平100
测定>98%
形式powder
reaction suitabilityreaction type: click chemistry

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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